68 search results for “oncology” in the Public website
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Advancements of interventional oncology treatments for early stage hepatocellular carcinoma
PhD defence
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Improving Side-effects and Quality of Life of Systemic Therapy in Oncology
PhD defence
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Two KWF grants for LUMC on AI for precision oncology
This week, the Dutch Cancer Foundation (KWF) has awarded two research grants to LUMC researchers that include the development of advanced AI technology to improve and personalize oncological treatment.
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Bleeding in hemato-oncology patients
PhD defence
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Applied Machine Learning in Neurosurgical Oncology
PhD defence
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Reproductive and sexual health care in oncology
PhD defence
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Statistics and Data Science
The group Statistical Science is responsible for research and teaching in statistics and data science.
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Leiden University Medical Center
The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.
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European Lead Factory
The European Lead Factory has been created with the ultimate goal to develop lead drug candidates to address neglected diseases including bacterial infections, psychiatric disorders and oncology.
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Coen van Hasselt
Science
coen.vanhasselt@lacdr.leidenuniv.nl | +31 71 527 3266
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Dutch Cancer Society allocates funds to a mathematician: for treating Ewing sarcoma with the help of an app
If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…
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Measuring shared decision making in oncology: An informed approach
PhD defence
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Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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KiKa grant for mathematician: how statistics helps fight bone cancer
Using mathematics to help children with bone cancer. It sounds a little strange, but for statistician Marta Fiocco, it's just her job. She gets a substantial grant from KiKa for it. With that money, she is going to study the effect of chemotherapy adjustments.
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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Statistical modelling of time-varying covariates for survival data
This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.
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Research groups
The research at The Metabolomics & Analytics Centre is centered around developing innovating analytical methods to enable metabolomics-driven systems biology in personalized health strategies.
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Admission requirements
The maximum number of students that can be enrolled in the first year of the programme of the master Biomedical Sciences at LUMC is 100.
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Statistical Science
The research programme Statistical Science is concerned with the analysis and interpretation of masses of data, the quantification of uncertainty using probability models, and the development and benchmarking of algorithms and methods with these aims.
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Quantitative Systems Pharmacology
This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).
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Control theory methods for quantitative systems pharmacology models
Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.
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Quantitative Pharmacology
The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…
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Statistics for the benefit of the patient
Marta Fiocco has been appointed as of 1 April as professor of applied mathematics, in particular medical statistics. Fiocco's appointment is at the Faculty of Science and at the Leiden University Medical Centre (LUMC). She conducts research into 'personalised medicine', tailor-made medicines for cancer…
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New professor wants to improve care for sarcoma patients
Doctors should work with patients with bone and soft-tissue tumours to find the best personal treatment strategy says Prof. Michiel den de Sande. He has developed an app that helps choose the right treatment. Van de Sande was appointed Professor of Orthopaedics with a particular focus on paediatric…
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Tailor-made medicines
More and more medicines are becoming available that target a tumour’s specific traits. The use of chemotherapy is continually undergoing improvement.
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Stress, hormones and emotion regulation
What is the role of stress and stress-related hormones in emotion regulation?
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Topic: The placebo and nocebo effects of communication
We study how communication can heal and harm when patients are confronted with an illness. Most of our studies focus on serious illnesses such as advanced cancer. Communication lies at the heart of medicine, yet we do not always know which specific communication helps patients. Moreover, many complaints…
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New collaboration aims to predict cancer survival
Predicting cancer survival with machine learning, that is the aim of a new collaboration between the Mathematical Institute, the European Organisation for Research and Treatment of Cancer (EORTC) in Brussels and Leiden University Medical Center. The focus of this project is to characterise the model…
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Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
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Dynamic personalised sarcoma care: implementation of a mathematical prediction app in the clinic
A new app provides dynamic predictions of survival for patients suffering from soft tissue sarcoma. It was developed by the mathematical Institute research group DASPO, Data Analysis and Survival for Personalised Oncology.
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Research
An overview of the research at the Cancer Dug Target Discovery group.
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Rob van Wijk discusses the role of zebrafish in drug discovery
Rob van Wijk gave an interview on the role of zebrafish in drug discovery and development, published in FIGON’s journal Medicines as a preview of LACDR’s representation at the PhD competition during the Dutch Medicines Days (DMD). The entire interview can be read below.
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Company Visit Ocello
On the 21st of September, seven students of SBB visited OcellO at the Biopartner 2.
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Child Cancer Fund subsidises statistical research
Marta Fiocco, professor in the Mathematical Institute, has received a grant for analysing data on chemotherapy in children suffering from leukaemia. The work involves developing and applying new statistical methods that will help determining the optimal dose of chemotherapy.
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Two grants for LUMC on AI for precision diagnostics
Two AI research projects receive funding; one in the field of oncology and one in the field of cardiology.
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Important developments in lung cancer surgery
Professor of Cardiothoracic Surgery, in particular pulmonary surgery, Jerry Braun will give his inaugural lecture on Friday 23 September entitled ‘Out of countless millions’. Braun has been a professor and acting head of the LUMC’s Department of Cardiothoracic Surgery since January 2020. Covid meant…
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Vidi grants for 12 researchers from Leiden University
An impressive 12 researchers from Leiden University have been awarded an 800,000-euro grant by the Dutch Research Council (NWO). This will enable them to develop their own line of research over the next five years.
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IBL-strategy meeting in Noordwijkerhout
Scientific director Herman Spaink brought almost all scientific staff members of our institute together in Noordwijkerhout for a two-day meeting about strategies for the future.
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Spinoza and Stevin prizes for LUMC professors
Sjaak Neefjes, professor of Chemical Immunology at the LUMC, has been awarded a Spinoza prize of 2.5 million euros. His colleague Ton Schumacher, professor of Immunotechnology affiliated with Leiden University, the LUMC and the Antoni van Leeuwenhoek cancer centre, has been awarded the Stevin prize,…
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Specialised immune cells have potential for new cancer immunotherapies
Researchers from Leiden University Medical Center (LUMC) and Netherlands Cancer Institute (NKI) have discovered how specialised immune cells can detect and remove cancers that are ‘invisible’ to the conventional defence mechanisms of the immune system. Their work has been published in Nature. The findings…
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I think that we can establish the best eye radiation chain in the world
Annually, approximately 60.000 people in the Netherlands undergo radiation therapy for cancer. Coen Rasch is dedicated to enhancing the precision of proton therapy.
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Florence Nightingale Colloquium
Here you can find the recordings of previous Florence Nightingale Colloquia.
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Psychology
The Institute of Psychology is committed to play a prominent role in teaching and research at the national and international level.
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Snake venom glands grown in lab
For the first time, researchers were able to grow organoids from snake venom glands. The lab-grown 3-D structures can produce snake venom molecules. This is a major step in finding treatments to tackle snakebite, which causes over 100,000 deaths each year. Publication in top journal Cell.
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Matching medication to DNA leads to 30% fewer side effects
According to the LUMC, patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.
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Three new Leiden members of KNAW
KNAW has elected eighteen new members, including two professors at Leiden University and one who studied and obtained his PhD in Leiden. The New Academy members will be installed at a later date this year.
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Leiden Professor convenes precision medicine workshop at Harvard's Radcliffe Institute
Professors Simcha Jong (Leiden University) and Rifat Atun (Harvard University) convened an exploratory seminar to discuss challenges for health systems in realising the potential of precision medicine at Harvard University’s Radcliffe Institute for Advanced Studies in Cambridge, MA on 17 April 2017.
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Tracing cancer with a simple blood test
Thanks in part to the persistence of a Leiden research group, cancer could be detected in the near future with just a single drop of blood. Not only can the diagnosis be determined at an earlier stage, but the blood test is also cheap, fast and patient friendly. The first results of this method seem…