5,279 search results for “activism” in the Public website
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Chemical tools to modulate endocannabinoid biosynthesis
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Cyclophellitol and its derivatives: synthesis and application as beta-glycosidase inhibitors
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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The Ra's al-jinz project (Oman)
The Ra’s al-jinz project tackles economic diversification and social complexity in non-urban societies, from the perspective of Eastern Arabia, by exploring the Early Bronze Age settlement of Ra’s al-jinz RJ-3.
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Astrophysical plasma modeling of the hot Universe: Advances and challenges in high-resolution X-ray spectroscopy
Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.
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The Picnic: A Dream of Freedom and the Collapse of the Iron Curtain
The gripping story of a collective passion for freedom that shook the world.
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Keep busy with these astronomy activities you can do from home
Stuck at home with little to do? Don’t worry, because we have the perfect space related activities you can do from home, alone or with your family, in Dutch or English.
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Transition from fossil to clean energy will reduce global mining activities
A wide range of metals need to be mined for solar panels, wind turbines and batteries. But the overall mining activity is set to decrease as clean energy replaces fossil fuels such as oil, coal and gas.
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Daredevil behaviour of young people due to active reward centre in the brain
Young people tend to take more risks than children or adults. This trend is related to the reward centre in the brain, which is much more active when they are rewarded, PhD candidate Barbara Braams discovered. Personality, testosterone levels and social context also play a role in risk-taking.
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Sylvestre Bonnet receives an ERC grant for light-activated chemotherapy
Chemist Sylvestre Bonnet has received a Proof of Concept grant from the European Research Council (ERC). With the grant of 150,000 euros, Bonnet will investigate whether chemotherapy that is activated by light can be used against eye cancer.
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Final project of the course Social and Ecological Activism in the Visual Arts (minor CSSC)
On 14 December 2022, students of the course Social and Ecological Activism in the Visual Arts (as part of the Creative Strategies for a Society in Change minor) presented and performed their final collective project at BAK, basis voor actuele kunst, Utrecht: the Water Cultures Institute group role-playing…
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CARICOM organises a pilot activity to teach regional integration in high schools
Awareness of the functioning of a regional integration process and the benefits it can offer is crucial for its success, as the European Union experience has proven.
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Volcanic ‘activity’ in black holes blows monumental bubbles of hundreds of thousands of light-years
An international team of researchers observed the full extent of the evolution of hot gas produced by an active black hole for the first time. As it evolves, the hot gas encompasses a much larger area than previously thought and even impacts objects residing at great distances. Their study is published…
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Sylvestre Bonnet
Science
bonnet@chem.leidenuniv.nl | +31 71 527 4260
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444 Interdisciplinary Activity Grant for Alex Brandsen and Wouter Verschoof-van der Vaart
Alex Brandsen and Wouter Verschoof-van der Vaart, PhD candidates in the Digital Archaeology research group and the Data Science Research Programme, have been awarded a 444 grant by Young Academy Leiden. They are going to use it to hold a session in Oxford on improving collaboration between researchers…
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Executive Board of the University asks University Council for advice on activating person counters/sensors
The Executive Board of Leiden University has asked the University Council to advise on its proposed decision to reactivate the person counters/sensors in due course. The Council will now look at this carefully before the Board makes a final decision. The advice of the University’s participation body…
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Heterogenized molecular (pre)catalysts for water oxidation and oxygen reduction
Before the large scale use of renewable energy sources can be implemented in our society, the storage of electrical energy needs to be tackled. Storage the energy as hydrogen via the reduction of protons is a good option.
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Active learning
Didactics
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Do fungi differ? Understanding the mechanisms of mycorrhizal fungal impacts on soil C sequestration
How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?
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The dust and molecular gas in the torus of NGC 1068
An Active Galactic Nucleus (AGN) is a highly luminous region at the center of a galaxy, powered by the accretion into a supermassive black hole and emitting energy from radio waves to gamma rays, often outshining the host galaxy.
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Inhibitors and probes targeting endo-glycosidases
The chemical synthesis of inhibitors and probes targeting endo-glycosidases.
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Inhibitors and probes targeting mannanases
This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…
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Wilson receive seed grant for their project 'Transnational Gay/Lesbian Activism since the 1960s'
Andrew DJ Shield (History) and Ann Marie Wilson (Leiden University College) have been awarded a seed grant for their project, “Transnational Gay/Lesbian Activism since the 1960s.” Granted: €3000.
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Mechanism-based inhibitors and probes for neuraminidases
Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.
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Gunay speaks on the EU’s responsibility for Frontex’s surveillance activities in the Libyan context
Between 18 and 20 October, CEPS (Centre for European Policy Studies) and the Migration Policy Centre of the European University Institute organized the ASILE training school for PhD researchers. The training focused on the concepts of responsibility attribution and accountability for fundamental rights…
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Using soil inoculations for ecological restorations
How soil microbial composition impacts structure and composition of the aboveground plant and animal communities?
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Cyclophellitol analogues for profiling of exo- and endo-glycosidases
To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.
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Geometry and Active Matter
PhD defence
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Martijn van der Lienden
Science
m.j.c.van.der.lienden@lic.leidenuniv.nl | +31 71 527 2727
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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Targeting Human Proteasomes: Substrates, Inhibitors and Prodrugs
Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.
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Visualization of Vitamin A Metabolism
Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.
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Synthetic model microswimmers near walls
Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.
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Photocleavable, Activity-Based Acid Glucosylceramidase Probes
PhD defence
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Click to Release for Immunce Cell Activation
PhD defence
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
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Teeth Tell Tales
A multi-disciplinary approach to past lifestyles and cultural practices
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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Machine learning for radio galaxy morphology analysis
We explored how to morphologically classify well-resolved jetted radio-loud active galactic nuclei (RLAGN) in the LOw Frequency Array (LOFAR) Two-metre Sky Survey (LoTSS) using machine learning.
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Applications of Natural Deep Eutectic Solvents to Extraction and Preservation of Biomolecules
The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.
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Zware metalen hebben slechte reputatie, maar genezen ook kanker
Veel mensen denken dat zware metalen giftig zijn en mens en natuur altijd schade aanbrengen. Dat beeld moet genuanceerd worden, vindt hoogleraar Sylvestre Bonnet.
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Rubicon grant for Leiden physicist: why do leaves of a tree always grow in the same shape?
PhD candidate Ludwig Hoffmann will spend two years at Harvard University in the US thanks to a Rubicon grant he won on April 11. Using theoretical models he studies biological tissues, for example during morphogenesis. This is the process that causes tissue or organisms to develop their shape. ‘This…
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Home sweet home
Investigating Neolithic houses in Britain through microwear and residue analysis of stone tools
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Leiden academics nominated for Person of the Year
Leiden academics Remco Breuker and Auke-Florian Hiemstra stand to win the title of Person of the Year.
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel
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Optimizing physical activity and exercise in people with axial spondyloarthritis
PhD defence
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Chemical Protein Synthesis: from Nanobodies to Activity-Based Probes
PhD defence
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Implementation of physical activity recommendations in people with axial spondyloarthritis
PhD defence
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Language diversity, education, and activism in multilingual Mexico
Lecture, Sociolinguistics & Discourse Studies Series