52 search results for “gene” in the Student website
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ERC grant for Sebastian Pomplun to precisely influence gene expression
In order to stop a whole range of diseases or disorders at their source, you would have to be able to switch certain genes on or off. Sebastian Pomplun wants to develop substances that can do this very precisely. For example, he wants to disrupt cancer processes and make cells produce an important missing…
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First patient in the Netherlands successfully treated with stem cell gene therapy
Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…
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Priyanka Chopra
Science
p.chopra@biology.leidenuniv.nl | +31 71 527 1886
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Guillermo Guerrero Egido
Science
g.guerrero.egido@biology.leidenuniv.nl | +31 71 527 4791
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Merijn de Bakker
Science
m.a.g.de.bakker@biology.leidenuniv.nl | +31 71 527 5043
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Manon de Visser
Science
m.c.de.visser@biology.leidenuniv.nl | +31 71 527 4882
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Remus Dame
Science
rtdame@chem.leidenuniv.nl | +31 71 527 5605
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Paul Hooykaas
Science
p.j.j.hooykaas@biology.leidenuniv.nl | +31 71 527 4933
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Salma Balazadeh
Science
s.balazadeh@biology.leidenuniv.nl | +31 71 527 4790
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Chao Du
Science
c.du@biology.leidenuniv.nl | +31 71 527 4947
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Pingtao Ding
Science
p.ding@biology.leidenuniv.nl | +31 71 527 5306
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Tom van der Wel
Science
t.van.der.wel@lic.leidenuniv.nl | +31 71 527 3534
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A computational tool that will transform bacterial genome analysis
Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.
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NWA grant for health law as part of NWA Cure4life
Mirjam Sombroek, Aart Hendriks and Martine de Vries (LUMC) will work on mapping the ethical and legal aspects of gene therapy. The aim is to establish a best practice of how society can best deal with these therapies. For example with guidelines on how to regulate, reimburse and make these therapies…
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Supergenes make bizarre traits possible
Within the same species of butterfly many different wing patterns can occur. How is this possible? According to researchers Ben Wielstra and Emma Berdan, of the Institute of Biology Leiden (IBL), the answer lies within supergenes. A supergene is a part of a chromosome that contains many strongly linked…
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Artificial intelligence helps in the search for new antibiotics
With the search for new antibiotics becoming increasingly urgent, artificial intelligence offers valuable help. Smart software developed by Leiden PhD candidate Alexander Kloosterman searched genomes of bacteria and found clusters of DNA that code for proteins that have an antibiotic effect. ‘This new…
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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Wood formation further explored by NWO-XL grant
Leiden researchers, Professor Remko Offringa and co-applicants Salma Balazadeh and Frederic Lens received an NWO-XL grant (2.5 million euros). Together with researchers in Wageningen and Groningen, they will study the genetic and environmental drivers of woodiness. From plant to molecule, the groups…
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Sibel Bahtiri is one of the new Faces of Science: ‘I want to show how we’re finding alternatives to animal testing’
PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.
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New SPARXS technique reveals DNA behaviour at unprecedented speed
Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…
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‘Homo sapiens is too arrogant: call us Homo faber, the toolmaker’
We need to dispel the arrogant and misguided idea that modern humans are superior to earlier human species. It is thanks in part to all our predecessors such as Neanderthals that we are who we are today. This is what Marie Soressi, Professor of Hominin Diversity Archaeology, will argue in her inaugural…
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King of Sweden visits Leiden University
Collaborating in drug discovery and health research was the goal of a visit to the Leiden Bio Science Park on 14 May by a Swedish delegation including His Majesty King Carl XVI Gustav of Sweden. The delegation visited Leiden University’s Faculty of Science.
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Richard Karlsson Linnér: ‘I expect a future where a genetic test will be as much a no-brainer as getting X-rayed.’
Assistant Professor Karlsson Linnér, who works at the Department of Economics, is one of the recipients of a Veni grant. His research on the accuracy of preventive genetic testing is a fine example of the intersection of economic science and law.
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Students build software for real customers
Students gain practical experience while clients receive a solution to their software needs: the student software company LUDev hits two birds with one stone. ‘Through LUDev, students learn what else is involved in software development besides programming.’ Interested? You can now submit new projects…
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From droplets in the freezer to the inception of a potent new antibiotic
What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…
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Bioart plays with genetic building blocks
Biotechnological developments are moving fast. From genetically modified plant varieties we are now moving to cultured meat. These developments require moral interpretation - and they get it in the form of art. Lotte Pet wrote a dissertation about it.
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New Master’s programme in Transfusion Medicine and Cellular and Tissue Therapies
LUMC and Leiden University will start the new two-year online master's program in Transfusion Medicine and Cellular and Tissue Therapies from October 2023.
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Medical Delta Professor Eline Slagboom: ‘The delta region is where everything comes together’
Professor Eline Slagboom has been studying multiple generations of families for over 20 years. She collects data on why some people age healthily and others decline early.
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Not wrapping but folding: Bacteria also organise their DNA (but they do it a bit differently)
Some bacteria, it turns out, have proteins much like ours that organise the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for Biology. The discovery helps us better understand…
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Where does this Inca language come from? Verb conjugations should provide some answers
When university lecturer Martine Bruil was on exchange in Ecuador as a teenager, she fell in love with the area's ancient languages. Now, more than 20 years later, she is starting a research project on the kinship of the language Awapit with the Quechua language that was spread by the Incas.
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Researchers tackle antibiotic-resistant bacteria
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…
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Education that connects to market needs: new course for master’s students focuses on quality in drug development
Immediately connect with the needs of industry with your master’s degree. The new course Practical Aspects of Quality Management in Pharma and Biotech provides just that. The LACDR and LUMC set up the course together with the Biotech Training Facility, located at the Leiden Bio Science Park. The first…
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Are the brains of males different from those of females? Psychologists produce a podcast on brain research and mental health
Women are more often diagnosed with depression, whereas ADHD is much more frequently detected in men. And there are other more striking differences. What role does the brain play in mental health and what is the influence of the environment? For answers to these questions, listen to the ‘(Un)gendered…
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Vincent Niochet investigates intercultural connectivity in the deep past with an NWO PhDs in the Humanities grant
For already two years, Vincent Niochet has been affiliated with the Leiden Faculty of Archaeology as an external PhD candidate. Now, he has been awarded an NWO PhDs in the Humanities grant, allowing him to continue his research as a paid PhD staff member. ‘The past two years have been quite challenging,…
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Promising new technique to treat cancer receives NWO grant
Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…
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'One in five bacteria we tested were capable of breaking down plastic'
Leiden PhD candidate Jo-Anne Verschoor discovered that nearly twenty percent of the bacterial strains she studied could degrade plastic, though they needed some encouragement to do so. ‘Bacteria are just like people,’ says Verschoor. Her research was published in the journal Communications Biology,…
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3 October University: from Russian DNA to drug-related violence
In prehistoric times there was a huge wave of migration, from the steppes in Russia and Ukraine to West Europe. The newcomers’ genes began to dominate. Archaeology research in Leiden into burial mounds in the Veluwe and Utrechtse Heuvelrug areas of the Netherlands yielded this spectacular conclusion.…
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Back to the scanner: brain science in times of corona
For their research many neuropsychologists use the brain scanners at the LUMC. At the start of the pandemic, the rules for visiting the hospital became stricter and a large amount of psychology research looked as though it would fall through. Thanks to good protocols the researchers can now pick up…
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Lecture by geneticist David Reich about the spread of the Indo-European languages
Lecture
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They came, they saw, they left: on the first humans in the Low Countries
Over hundreds of thousands of years, our region witnessed the comings and goings of various types of hominin. This depended on the temperature as ice ages alternated with warmer periods. In ‘De eerste mensen in de Lage Landen’ (‘The First Humans in the Low Countries’) Leiden archaeologists Yannick Raczynski-Henk…
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Students work on bacterium that makes sustainable plastic
A group of biology students are working on a solution to the world’s plastics problem by getting bacteria to make biodegradable plastic.
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Nutrition and fasting for the brain: why the Keto diet shows promise
Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.
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Stiffness and viscosity of cells differ in cancer and other diseases
During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.
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‘Children’s healthcare rights deserve more attention’
‘Children’s rights are somewhat of a poor relation’, says Professor of Law and Health Mirjam Sombroek-van Doorm. In her inaugural lecture, she will emphasise how more attention needs to be paid to children’s rights in current thinking on law and health.
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How Oncode-PACT is bringing new cancer medicines closer with 325 million in Growth Fund money
How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…
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Joint Lectures on Evolutionary Algorithms (JoLEA)
Lecture
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LIBC Colloquium
Lecture
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SAILS Lunch Time Seminar
Lecture
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SRS seminar series
Seminar series
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How do you help a child suffering from depression?
What causes depression in a child and how can they get over it? Leiden Professor of Psychology Bernet Elzinga and behavioural scientist Carine Kielstra recently hosted a webinar on the subject of depression in teenagers. The level of interest was overwhelming.