221 search results for “drug” in the Staff website
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Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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Gene Networks-based Mechanistic Assessment of Drug-induced Organ Toxicity
PhD defence
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Is a cancer pill a matter of time?
A cancer pill, preferably without severe side effects, is something we’d all welcome. Is it a matter of time before such a pill is a reality? We put this question to three Leiden researchers and asked how they themselves are contributing to new cancer treatments.
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Data stewards
Do you have questions about data management? Please contact the data stewards:
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With this algorithm, new medicines can be found more quickly
Did he dare take a gamble with his PhD research? Jeroen Methorst didn’t have to think long about it. It could fail or turn out very well. The latter is the case. Methorst developed a computer system that helps researchers find the protein they need. ‘Our whole group is now using this program.’ Methorst…
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In conversation with the head of the rodent facility
Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…
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Serkan Aslan
Science
s.aslan@lacdr.leidenuniv.nl | +31 71 527 5919
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Erik Danen
Science
e.danen@lacdr.leidenuniv.nl | +31 71 527 4486
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Tom van der Wel
Science
t.van.der.wel@lic.leidenuniv.nl | +31 71 527 3534
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Veni grants for 21 researchers from Leiden University
An impressive 21 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).
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Promising new technique to treat cancer receives NWO grant
Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…
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Rob van Wijk
Science
r.c.van.wijk@lacdr.leidenuniv.nl | +31 71 527 4505
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ICT-contact persons
For each university unit, the ICT Shared Service Centre (ISSC) has an appointed ICT contact person responsible for applying for ICT facilities for research, teaching and operational management.
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Sebastian Pomplun joins Oncode Institute to accelerate breakthroughs in cancer research
Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…
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Master student Nicole ter Laak wins third “Dr. Saal van Zwanenberg research price”
Nicole ter Laak (Master student Biopharmaceutical sciences) has won the third price of the “Dr Saal van Zwanenberg research price”. The award ceremony is on 14 November.
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€10.6 million for innovative toolboxes to tackle brain cancer
Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…
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Selective cannabinoid CB2 receptor activation in Nature Communications
This March, Jara Bouma, Cas van der Horst and Laura Heitman from the Division of Drug Discovery and Safety and Laura de Paus, Richard van den Berg, Anthe Janssen and Mario van der Stelt from the LIC joined forces to determine how some drugs can specifically target the cannabinoid CB2 receptor (CB2R)…
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Zware metalen hebben slechte reputatie, maar genezen ook kanker
Veel mensen denken dat zware metalen giftig zijn en mens en natuur altijd schade aanbrengen. Dat beeld moet genuanceerd worden, vindt hoogleraar Sylvestre Bonnet.
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Pharma-NL application submitted to National Growth Fund
The Ministry of Health, Welfare and Sport (VWS) submitted Pharma-NL to the R&D program of the National Growth Fund, a 20 billion euro program of the Dutch government that intends to create long-term economic growth in The Netherlands.
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Referral options
If you’re unsure where to refer students to for well-being support, this page should help. It provides an overview of the support available at Leiden University.
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Two new Directors for IBL
The Institute of Biology Leiden (IBL) has appointed two new directors. Maribel Adame Valero will become the new Director of Operations on 1 August, and Hubertus Irth will start as the new Scientific Director on 1 September. This completes the new collegial management for IBL, following the earlier appointment…
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Leiden researchers join forces against tuberculosis
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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Joke Bouwstra is the first woman to receive the Dr Saal van Zwanenberg Honorary Prize: 'Wonderful to be in a line of distinguished scientists'
Emeritus professor Joke Bouwstra (LACDR) will receive this year's Dr Saal van Zwanenberg Ereprijs: a tribute to her years of fundamental research on the skin and the transport of drugs through the skin. This is the first time the prize has gone to a woman.
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Professor and Knight: Joke Bouwstra Receives Royal Honor
A memorable farewell symposium and a royal distinction: Professor Joke Bouwstra could not have completed her career at Leiden with more pleasure. On Friday, 14 June, she received a Royal Honor from Leiden Mayor Peter van der Velden, who appointed Bouwstra as a Knight in the Order of the Dutch Lion for…
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LACDR EMA Lunchtalk
On Friday the 29th of October, LACDR presented highlights of its research and teaching program during an online Lunchtime Talk session at the European Medicines Agency (EMA).
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Willem Jespers wins the international Rottendorf Foundation Award for Pharmacy and Pharmacology 2023
Willem Jespers was awarded the international prize, worth €10,000, for pharmacy and pharmacology from the Rottendorf foundation on October 13th 2023 at the University of Münster. He was recognized for his research in the field of computer-aided drug development and the prediction of drug toxicities.…
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Successful symposium on Circuit Topology
On the 8th of December 2021, Leiden Academic Centre for Drug Research (LACDR) organized “Circuit Topology 2021”, the first international symposium on circuit topology. The focus was on the mathematical notion of Circuit Topology, and its applications to physics, chemistry and biomedicine.
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Versatile antiviral proteins discovered with supercomputer
A single tiny molecule that can destroy flu, corona, HIV and Zika viruses? Yes, it really does exist. Biophysicist Niek van Hilten, who will receive his doctorate on 14 September, contributed to this discovery.
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Better treatment of skin diseases thanks to NWA grant of 11.7 million euros
Patients with skin diseases such as eczema and psoriasis, sometimes spend a lifetime searching for the right medication. To help these patients faster and better, scientists across the country are joining forces. The Next Generation ImmunoDermatology (NGID) project, with LACDR professor Robert Rissmann…
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Developing new therapies to fight muscle disease
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…
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Awarded research project Next Generation ImmunoDermatology: Towards Biomarker-driven Dermatology practice in the Netherlands
The Dutch Research Council (NWO) has, within the framework of Research along Routes by Consortia (NWA-ORC), awarded the research project Next Generation Immuno-Dermatology (NGID) with a prestigious grant of 11.7 MEuro. NGID is a nationwide, large-scale project to unravel novel biomarkers for six different…
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…
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Wanda van der Stel - ALTEX Prize Winner 2022
The members of the Board of ALTEX Edition, the ALTEX Editorial Board and ALTEX Editorial Office elect the winner of the annual award out of all main articles published in the previous year; articles including members of the Board of ALTEX Edition or ALTEX Editorial Office as first authors are excluded.…
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ULLA workshop – summer school - courses
We are proud partner of the ULLA. It is the European University Consortium for Pharmaceutical Sciences in which LACDR participates for already 30 years. We have the honor to host the ULLA workshop in 2023 and the ULLA summer school in 2024.
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Prof Dr Joke Bouwstra receives the “ Dr Saal van Zwanenberg Ereprijs”
Prof Dr Joke Bouwstra will receive the “ Dr Saal van Zwanenberg Ereprijs” from the “Koninklijke Hollandse Maatschappij der Wetenschappen” on November 14 in Haarlem. Joke is awarded for her innovative contributions to the field of skin delivery science and technology. She shares the price with prof…
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Tamara Danilyuk wins the EUROTOX 2023 Early Career Award
I am thrilled to share the exciting news of being honored with the 2023 Early Career Award at the EUROTOX conference held in Ljubljana, Slovenia. This recognition, presented by ECETOC (European Centre for Ecotoxicology and Toxicology of Chemicals) and dedicated to the memory of Dr. Christa Hennes, holds…
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Interview Micha Drukker
Micha Drukker
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Nature Communications paper on therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.
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Interview
Sabine de Winter
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700,000 euros for the fight against aggressive breast cancer
To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…
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EUFEPS congres
EUFEPS Women in Pharmaceutical Sciences Award for Jara Bouma
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Erik Danen new Dean of the Graduate School of Science
The Graduate School of Science starts 2024 with a new Dean. The Faculty Council appointed Erik Danen for the coming four years. He succeeds Eric Eliel, who has held the position since May 2020.
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Improving nature’s antibiotic
'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…
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Study associations sign covenant: limit your alcohol consumption and look after each other
Opting more often for mocktails or soft drinks rather than beer or wine, talking to others about their drinking and pointing out the ban on drugs. Leiden University’s new covenant on alcohol and drugs for study associations encourages providing more alcohol-free alternatives.
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Superselective bonds light up
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…
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Seven Comenius grants for Leiden lecturers
Eleven lecturers from Leiden University have been awarded Comenius grants that will allow them to work with their teams on an innovation project within their own teaching. They have been awarded three grants of 100,000 euros within the Senior Fellows programme and four grants of 50,000 euros within…
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Sibel Bahtiri is one of the new Faces of Science: ‘I want to show how we’re finding alternatives to animal testing’
PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.
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Carlijn Lems wins the Suzanne Hovinga Award 2020-2021
During the LACDR Fall Symposium the Suzanne Hovinga Award for ‘best master thesis’ was awarded to Carlijn Lems for her master thesis entitled ‘Elucidating the crosstalk between epithelial-to-mesenchymal transition and Programmed Death-Ligand 1: validation and extension of a computational model’. Carlijn…