127 search results for “brecht center metastasis” in the Public website
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Leiden researchers discover genes that affect spread of breast cancer
Researchers at Leiden University have mapped genes that cause breast cancer cells to migrate. The Leiden toxicologists Professor Bob van de Water, Dr Wies van Roosmalen, Dr Sylvia E. Le Dévédec and colleagues studied 1500 individual genes. They found eight, including the SRPK1 gene, that regulate the…
- Leiden Academic Centre for Drug Research
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Erik Danen appointed as Professor of Cancer drug target discovery
As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.
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30 million for Dutch Center for Biodiversity
Universiteit Leiden in cooperation with Naturalis, the University of Amsterdam (UvA) and University Wageningen is foundig a center for biodiversity. They will receive 30 million euros from The Ministry of Education, Culture and Science (OCW).
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Ewa Snaar-Jagalska
Science
b.e.snaar-jagalska@biology.leidenuniv.nl | +31 71 527 2727
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The IBL at Science Center NEMO
Professor Annemarie Meijer and several students explained to more than 8000 visitors the zebrafish as a model for research during the National Weekend of Science (3-4 Oct) at Science Center NEMO in Amsterdam.
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Role of Chemokine Gradient Sensing in Ewing Sarcoma Progression, Angiogenesis and Immune Targeting
What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?
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Thomas Schmidt Lab - Single Molecule Microscopy
Intrigued by the way cells autonomously regulate their fate, we strive to understand and visualize cellular processes as the basis of Cell Signaling.
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Luca Giomi Group - Soft and Bio Mechanics
We are interested in understanding the mechanics of soft materials, of which biological materials are prominent examples.
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Opening Museum and research center Paläon
One of the highlights during the fieldwork in Schoningen lead by Prof. dr. Thijs van Kolfschoten in 2013 was the opening of the museum and research center paläon on June 24. To the realisation of the museum, the Faculty of Archaeology made a significant contribution. Many of the results of the research…
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Lorentz Center to receive structural support from NWO and Leiden University
The Lorentz Center is a melting pot that is visited by researchers from around the world. ‘Miracles happen’ during the five-day interactive workshops at the Center. And there is an extra reason to celebrate the center’s 25th anniversary. On 28 April, the Dutch Research Council (NWO) and Leiden University…
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25 September, 2015: Opening Central and East European Studies Center
Friday 25 September, 2015 marks the official launch of Leiden University's Central and East European Studies (CEES) Center.
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NEW!! Bonn Center for Dependency and Slavery Studies
The University of Bonn, Germany, is happy to announce the opening of the Bonn Center for Dependency and Slavery Studies (BCDSS).
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Lorentz Center brings together researchers from all disciplines
For nearly twenty years the Lorentz Center has been a unique venue where researchers from all over the world work in intense collaboration. In an inspiring academic climate, researchers are free to organise specialised workshops within and across disciplines, be it humanities, social sciences or sci…
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How oxygen deprivation causes cancer cells to spread
In breast cancer, metastasis rather than the primary tumour is the cause of death. A lack of oxygen in the tumour cells promotes this metastasis, accompanied by a reprogramming of the cell's metabolism. PhD candidate Qiuyu Liu investigated these alterations to get more knowledge about the actionable…
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Osteosarcoma: searching for new treatment options
Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen
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Computational Biology
Projects within the theme ‘Computational Biology’ aim to employ mathematical or computational dynamical modelling approaches to discover novel concepts that are important for drug development.
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GLOBTAXGOV team meets Inter-American Center of Tax Administrations
On 15 March 2023, the GLOBTAXGOV team at Leiden Law School met with the Inter-American Center of Tax Administrations (CIAT) to explore opportunities for cooperation, to discuss the needs of tax administrations in the field of international taxation and evaluate ongoing projects and new initiatives where…
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Small molecule prevents tumour cells from spreading
Leiden chemists, together with colleagues at the University of York (UK) and Technion (Israel) have discovered a small, sugar-like molecule that maintains the integrity of tissue around a tumour during cancer. This molecule prevents tumour cells from spreading from the primary cancer site to colonise…
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PI3K signaling and adherens junctions in invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.
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Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
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Modelling metastatic melanoma in zebrafish
Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.
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Twentieth anniversary of the Lorentz Center: developing ideas in a scientific bubble
The 20th anniversary of the Lorentz Center will be celebrated on 28 June 2017 with the opening of an exhibition in the Oude UB. For two decades already, the Center has been a place of retreat for groups of international academics who want to explore a single issue.
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Jan Kolen Director of LDE Center for Global Heritage and Development
Archaeologist Professor Jan Kolen has been appointed Director of the LDE Center for Global Heritage and Development (CGHD) with effect from 1 July 2013. This new inter-university heritage center is due to start in the autumn of 2013 within the framework of the strategic alliance between Leiden University,…
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Jeanette Satink visits the Beijing Children's Legal Aid and Research Center
At the end of March Jeanette Satink visited the Beijing Children's Legal Aid and Research Center.
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Research Presentation Wico Breimer 13 December @ 11:00 hrs, Gorter Center, LUMC
The project has been done in the High field MRI and clinical applications department under the supervision of Prof.dr. Andrew Webb. The title of the presentation is: ''Developing an Open Source Budget-MRI Using Permanent Magnets.
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700,000 euros for the fight against aggressive breast cancer
To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…
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KNAW grant awarded for ‘People-centered constitutional law’ research project
Recently, Wim Voermans, Professor of Constitutional and Administrative Law, and Jaroslaw Kantorowicz, Assistant Professor at the Institute of Security and Global Affairs and a research associate at the Department of Economics, were awarded a grant from the KNAW Statesman Thorbecke Fund. This grant will…
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Drug Discovery & Safety
In the research programme Drug Discovery & Safety, we are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.
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Cancer Drug Target Discovery
In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…
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programme International Children’s Rights visit Dutch juvenile detention center De Hunnerberg
On 25 October 2017, the current class of students of the advanced LL.M. programme International Children’s Rights visited juvenile detention center ‘De Hunnerberg’ in Nijmegen (the Netherlands).
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‘Science Based Rules on Plastic: Regulating Plastic Pollution’ at Lorentz Center
From 27 to 31 January, a workshop on the regulation of plastic pollution based on scientific evidence will be held at the Lorentz Center in Leiden.
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Delegation from Czech research center visits Leiden’s Faculty of Science
On 3 and 4 June 2015 a delegation from the biotechnology and biomedicine center in Prague (BIOCEV) visited the Faculty of Science in Leiden, as well as the Netherlands Centre for Electron Microscopy (NeCEN). The delegation was interested to see the potential for collaboration in the field of cryo transmission…
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How metastatic tumours manipulate their environment
Tumours act like mini-organs, manipulating their environment and using bodily processes to survive and metastasise. Through research by Erik Danen and his colleagues, we are learning more about the complex nature of tumour cells. In the Dutch newspaper NRC, the scientists discuss their findings.
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Vasiliki Kosta appointed Emile Noël Fellow at the Jean Monnet Center of New York University (NYU) School of Law
Vasiliki Kosta has been appointed Emile Noël Fellow at the Jean Monnet Center of New York University (NYU) School of Law after a competitive selection process.
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PROPER: ‘Near-patient’ prostate cancer models for the assessment of disease prognosis and therapy
How to identify patients at risk of developing devastating, metastatic disease and facilitate the development of personalised treatment for prostate cancer patients?
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Third annual conference of the Leiden Center for East African Law at Strathmore University, Nairobi
On the 27th April 2017, the third annual conference of the Leiden Center for East African Law (LEAC) took place at Strathmore University in Nairobi, Kenya. The theme of the conference was ‘East African Law: A Common Market, Opportunities and Challenges for the Business Community’.
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Development of novel anti-cancer strategies utilizing the zebrafish xenograft model
In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…
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Cell Systems and Drug Safety
The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…
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Work-in-Progress seminar at the Center of Multimodal and Audio-Visual Methods (ReCNTR)
Team ReCNTR gives feedback on the Food Citizens? I-doc
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Bob van de Water
Science
water_b@lacdr.leidenuniv.nl | +31 71 527 6223
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Centre for Art, Literature and Law (CALL)
The center studies the many ways in which issues of law and justice are dealt with in art and literature with a focus on liminal issues and cases. These are issues and cases where law comes to the limits of what it is capable of dealing with and art and literature explore the implications of what is…
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New zebrafish study to understand human cancer
Ewa Snaar-Jagalska, Shuning He and colleagues from IBL, LION and LACDR reported on a new zebrafish study to understand micrometastasis of human cancer cells. They discovered a novel role for neutrophils in assisting metastasis formation, which provides critical insights for anti-cancer therapies.
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Kosta speaks ‘on the principle of proportionality in EU law’ at the Center for Political and Constitutional Studies, Madrid (Centro de Estudios
Vasiliki Kosta participated in the García Pelayo Seminar of the Center for Political and Constitutional Studies, Madrid entitled: ‘Discretionary Powers and Judicial Review: What Destiny for the Principle of Proportionality?’
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Successful second annual conference of the Leiden Center for East African Law at the EAC headquarters in Arusha
On the 5th of May 2016, the second annual conference of the Leiden Center for East African Law (LEAC) took place at the East African Community headquarters in Arusha, Tanzania. The Conference was organized on the occasion of Europe Day with the generous support of the EAC, the EU delegation to EAC and…
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Photosynthetic light reactions at the gold interface
Promotor: Prof.dr. T.J. Aartsma, Co-promotor: R.N. Frese
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UM Cure 2020: New therapies for uveal melanoma
Can we bring novel treatment options to the clinic for UM patients with liver metastases?
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Science for Society
By carrying out fundamental research and providing excellent education, universities become a breeding ground for innovation and entrepreneurship.
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.