2,585 search results for “modelling ” in the Public website
-
LCN2 Seminar: Discordant edges for the voter model on regular random graphs.
Lecture
-
3D modeling and RNA-based therapeutics for Dutch-type Cerebral amyloid angiopathy
PhD defence
-
LTA lunch lecture: Can you send me a 3-D model?
Lecture
-
Pronunciation variation in the Buckeye corpus: modelling the impact of age and gender
Lecture, Sociolinguistics Series
-
pathogenesis underlying bicuspid aortic valve disease using new disease models
PhD defence
-
Advanced tools and methods for modeling cardiovascular disease using human pluripotent stem cells
PhD defence
-
epidemiologic methods on findings in studies of causal effects and prediction modelling
PhD defence
-
Fluorescent in vivo models for hematopoietic stem cell and lymphoid lineage analysis
PhD defence
-
In vitro models of bone-forming tumours: from target to treatment
PhD defence
-
Experimental pain models for the evaluation of next-generation analgesics in clinical pharmacology studies
PhD defence
-
therapies for mitochondrial cardiomyopathies using advanced human stem cell models
PhD defence
-
Modeling vascular disease using self-assembling human induced pluripotent stem cell derivatives in 3D vessels-on-chip
PhD defence
-
Glucocorticoid signaling in a rat model of post-traumatic stress disorder
PhD defence
-
Understanding and Targeting Coronaviruses Exploring advanced cell culture models and host-directed antiviral strategies
PhD defence
-
LED3 Lecture: Organoids to model human health and disease in vitro
Lecture
-
Cum laude PhD defence: natural seed bank drives diversity
Each year, poppies disperse seeds that grow into a new generation of flowers. Sometimes, some of the seeds postpone their germination for a few years, for example when they’re covered by a layer of sand. Only when the sand disappears, do they start to sprout. Margriet Oomen did mathematical research…
-
Towards circular and energy-efficient management of building stock
Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.
-
Three Leiden scientists receive NWO ENW-KLEIN grant for innovative research
The origins of Surinamese rice, a digital twin of the Earth and a large big-data project in the Chilean sky: three Leiden scientists receive an ENW-KLEIN grant for innovative, fundamental research.
-
How to determine medication dosages for premature babies
Premature babies almost always require treatment with medication. Doctors usually determine the dosages based on data from children who were not born prematurely, while preterm infants often develop differently. Medication researcher Aline Engbers investigated three commonly used drugs, focusing on…
-
LCN2 Seminar: Network model selection via the Minimum Description Length principle: the effects of ensemble non-equivalence
Lecture
-
Skin Lipids: Localization of Ceramide and Fatty Acid in the Unit Cell of the Long Periodicity Phase
The lipid matrix of the skin's stratum corneum plays a key role in the barrier function, which protects the body from desiccation. The lipids that make up this matrix consist of ceramides, cholesterol, and free fatty acids, and can form two coexisting crystalline lamellar phases: the long periodicity…
-
Generalized Strictly Periodic Scheduling Analysis, Resource Optimization, and Implementation of Adaptive Streaming Applications
This thesis focuses on addressing four research problems in designing embedded streaming systems.
-
Van Marum Colloquium: Thermodynamic modeling of the electrode-electrolyte interface - Double-layer capacitance, Solvation number, Validation
Lecture
-
Mechanistic insight and rAAV assays on mouse & human retinal organoid models
PhD defence
-
Preclinical and ‘near-patient’ models for the evaluation of experimental therapy in prostate and bladder cancer
PhD defence
-
Nano shapes micro : Impacts of metallic nanoparticles on microbial communities
This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.
-
Erik Danen
Science
e.danen@lacdr.leidenuniv.nl | +31 71 527 4486
-
Noortje Dannenberg
Science
n.dannenberg@biology.leidenuniv.nl | +31 71 527 5075
-
Tackling messy blood vessels to fight cancer
With a Vici grant of 1.5 million euros, Professor of Mathematical biology Roeland Merks will look for ways to fix messy and leaky blood vessels in tumours. His research combines mathematical simulations and lab experiments in a unique way.
-
Liesbeth de Lange wins Lewis B. Sheiner Career Prize
Pharmacologist Liesbeth de Lange has won the Lewis B. Sheiner Lecturer Award from the International Society of Pharmacometrics (ISoP). As Professor of Predictive Pharmacology she is working, among other things, on a mathematical model that can predict drug concentrations in the brain. On the occasion…
-
How do children's kidneys eliminate drugs?
What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…
-
Accelerating the Photocatalytic Water Splitting in Catalyst−Dye Complexes
As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.
-
Can we predict the future of ecosystems throughout the world?
To what extent does human intervention influence the world’s biodiversity? And can we predict how biodiversity and ecosystems will change in the coming years? Inaugural lecture by Peter van Bodegom, Professor of Conservation Biology, on 8 May.
-
Rob van Wijk
Science
r.c.van.wijk@lacdr.leidenuniv.nl | +31 71 527 4505
-
Hypoxic Signalling and Tuberculosis
IBL-researcher Phil Elks in the group of Annemarie Meijer won the Cell Observatory Publication of the Year 2013. He received the award for his paper in PLoS Pathogens, showing that activation of hypoxia signaling protects against mycobacterial infection.
-
R-ELEVATION
How do plant defense genes get activated?
-
The mysteries of exoplanets and supermassive black holes: two Vici grants for Leiden Observatory
One unravels the origin of the largest black holes in the universe, the other investigates the influence of stellar wind on the atmosphere of exoplanets. Both Elena Maria Rossi and Aline Vidotto receive a Vici grant for their research into the mysteries of the universe. ‘I have no idea yet how we can…
-
The endocannabinoid system in zebrafish larvae
In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.
-
Mismatched timing: how climate change challenges bird migration
How does climate change affect the migration routes of birds? Mainly negatively, according to a new study from Yali Si from the CML. ‘It changes the timing of natural events differently in each region,’ she explains. ‘This can lead to a growing mismatch between the availability of food and the supposed…
-
Studying the Benefits of Using UML on Software Maintenance: an Evidence-Based Approach.
Including modelling as part of software development appears to have various benefits.
-
Scientific computing for Drug Discovery in Python and/or R
Data analysis with Python and R are rapidly becoming essential skills for modern scientists. Therefore, we are offering courses to develop your scientific computing skills. Those courses are optional for LACDR PhD candidates.
-
Archaeological Prediction and Risk Management
Alternatives to current practice
-
Student projects
Are you looking for a research project?
-
Computational Biology
Projects within the theme ‘Computational Biology’ aim to employ mathematical or computational dynamical modelling approaches to discover novel concepts that are important for drug development.
-
Programme structure
The master's specialisation Methodology and Statistics in Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.
-
A game of Mastermind to unravel Alzheimer’s disease
In order to better understand the course of Alzheimer’s disease, Frédérique Kok believes that a strategic and structured approach is needed: the Mastermind research approach. With her LUF grant, Kok wants to generate high-quality data to build a mathematical model that can recognize the onset of the…
-
Into the Darkness: Forging a Stable Path Through the Gravitational Landscape
In this thesis we study the landscape of gravitational models which modify GR by introducing an additional scalar degree of freedom (d.o.f.) to source Cosmic Acceleration.
-
Quantitative Systems Pharmacology
This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).
-
Resampling Methodology for Longitudinal Data Analysis
How does the cluster bootstrap procedure in combination with various types of linear models perform in the analysis of longitudinal data, compared to other methods.
-
Data-driven donation strategies: understanding and predicting blood donor deferral
The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.