2,331 search results for “mexican drug violence” in the Public website
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Masullo & Morisi, The Human Costs of the War on Drugs
Citizens in multiple crime-ridden countries strongly support the militarization of security—that is, placing the military in charge of traditional policing duties. Yet, we know little about the determinants of such support. Do people approve of militarization even in the face of human fatalities? Political…
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Violence and Violence Prevention
The Research Group 'Violence and Violence Prevention' studies interpersonal violence. We seek to better understand the dynamics underlying interpersonal conflict.
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Lethal Violence
Research on lethal violence related to criminal activities.
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Mexican drugs world pans out into hybrid war
Drugs-related violence in Mexico is similar in terms of dynamics and strategy to the IS hybrid war in the West. This is the claim made by Teun Voeten. PhD defence 20 September.
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Drug-Related Homicide in Europe
Drug-related homicide (DRH) has the potential to act as a valuable indicator of wider drug-related crime. Yet DRH remains a knowledge gap within this broader field of study.
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Project TARGET: gun violence and firearms trafficking in Europe”
Project TARGET aims to improve our understanding of gun violence in Europe and the relationship between gun violence and firearms trafficking.
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Firearms and violence in Europe
Firearms and violence in Europe–A systematic review by Katharina Krüsselmann, Pauline Aarten, Marieke Liem
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Governance of Violence (MSc)
What is the nature and scope of violence? Who offends, and in what context? Who are the victims? And how can we design suitable intervention and prevention strategies? In this track, you will be familiarised with the many faces of violent offending, to provide the knowledge and tools to understand,…
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25 Years of Lethal Violence
How many men and women die per year at the hands of others? What are the motives behind these killings? Are there as many homicides today as years ago? How can we explain the rise and fall of homicides over time? And: What is the influence of (early) childhood and adolescence on the likelihood to commit…
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Pulling the Brakes on Political Violence
Under what circumstances do paramilitary groups limit their use of political violence? This article examines the use of political violence by the PIRA.
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Violence Studies
In this minor programme, students will become familiar with the nature and scope of violence; the ways in which it impacts public order, and the ways in which society can respond to and, ultimately, prevent violence.
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Terrorism and Political Violence
Understanding the evolving landscape of extremism in the 21st century.
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Drug research
In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.
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barking dogs bite: A comparison between fatal and non-fatal domestic violence
In this project, we seek to assess, map and understand the risk factors associated with fatal domestic violence.
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
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Conspiracy, legitimacy and violence
Can conspiracy constructions explain for hatred of the system? And if so, should conspiracy constructions be considered to be a risk in terms of national security?
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Novel target engagement biomarkers for better drug candidates
Is is possible to better predict the validity of drug candidates?
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Violence and the Oedipal Unconscious
Representations of violence are often said to generate cathartic effects, but what does “catharsis” mean? And what theory of the unconscious made this concept so popular that it reaches from classical antiquity to the digital age?
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Modern Drug Discovery
How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…
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Targeting gun violence & trafficking in Europe
To assess the impact of illicit firearms trafficking on gun violence, this research looks at the scope, characteristics and contexts of firearm violence, and also the scope and nature of firearms trafficking in Europe since the new millennium. Nils Duquet, Dennis Vanden Auweele and Marieke Liem created…
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Child victims and domestic violence
The judge as a problem-solver in domestic violence cases involving child victims.
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Drug Discovery & Safety
In the research programme Drug Discovery & Safety, we are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.
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Drug discovery pipeline
The drug discovery pipeline is used to describe the stages in drug discovery. The earliest stage concerns with the identification of potential targets and molecules ('hits') that can modulate their function, while more advanced stages are about developing these hits into viable experimental drugs and…
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Data-Driven Drug Discovery Network (D4N)
The Data-Driven Drug Discovery Network (D4N) is an initiative by researchers from Leiden University and collaborators to join efforts in applying and developing novel techniques from data science to drug discovery and related topics from bioinformatics.
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Drug safety Sciences
Our research in the area of safety sciences aims to increase the mechanistic understanding of cellular toxicity of drugs and, in a broader sense, chemicals.
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Cancer Drug Target Discovery
We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Computational Drug Discovery
Research in this group, headed by Gerard van Westen, focusses on computational methods integrated in different parts of the drug discovery process. More specifically, topics include innovative treatments for cancer, selectivity modeling, translational research, allosteric modulation, drug resistance…
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Cancer Drug Target Discovery
In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…
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Discovering and developing drugs
Improving healthcare with our scientific discoveries: that is the goal of pharmaceutical research at Leiden University. And there’s a lot involved in that. Our research starts with the discovery of the effect achieved by a particular substance, and sometimes continues all the way through to the development…
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Dynamics of TNFalpha signaling and drug-related toxicity
In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.
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Reverse engineering of drug induced QT(c) interval prolongation: Towards a systems pharmacology approach
Promotor: M. Danhof Co-promotor: O.E. Della Pasqua
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Debate: ‘A Crisis on the Rise? The Impact of Violence and Impunity on Mexican Society’
Mexico is currently facing an unprecedented social and political crisis, with expanding criminal and political violence, rampant impunity and crumbling political institutions. Next to the daily report of anonymous victims of violence, last summer in Central Mexico at least 15 citizens were executed…
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Drug Discovery and Safety (MSc)
The master's specialisation Drug Discovery and Safety at Leiden University provides students with research-oriented education into the discovery of new drug targets and new lead molecules, particularly in the field of cancer, through a combination of advanced imaging techniques (‘systems microscopy’),…
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Violence in institutions for juvenile offenders
This study focuses on violence involving juveniles in conflict with the law who are deprived of their liberty in different institutions within the framework of the (juvenile) criminal justice system (inter alia, police detention, pre-trial detention and deprivation of liberty after conviction or sen…
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Missing the Mark? A Typology of Lethal and Non-Lethal Firearm Violence in the Netherlands
This article describes the phenomenon of firearms violence and the importance of including non-lethal firearms violence in understanding this phenomenon.
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Towards a political ontology of violence: reality, image and perception
The aim of this project is to study what makes an act or form of violence a specifically political reality.
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Explosive Violence: Research into the Nature and Extent of Incidents with Hand Grenades in The Netherlands
The illegal use of hand grenades has generated a lot of public interest over the last few years but very little is known about the nature and extent of these incidents. This research project is trying to fill that gap.
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Unravelling cancer drug resistance mechanisms
Mechanisms fro drug resistance
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Collaborative and effective drug development
There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…
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Cell Systems and Drug Safety
The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…
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Leiden Early Drug Discovery & Development
Despite recent advances in medicine, many devastating disorders like cancer and cardiovascular, neurodegenerative and infectious diseases still lack effective treatments. In order to address this challenge, we, as scientists from Leiden University, joined hands in the LED3 network. LED3, for Leiden…
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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LED3 Drug Discovery Case Studies
To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.
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Translational drug discovery and development
We cover the entire spectrum from target identification to the evaluation of the efficacy and safety of novel medicines in clinical practice.
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LED3 Lecture: Computational Drug Discovery
Lecture
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LED3 Lecture: Covalent Drug Discovery
Lecture
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Prediction of spatial-temporal brain drug distribution with a novel mathematical model
A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.
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Kinetics for drug discovery – The first step towards an improved drug discovery paradigm
Supervisor: Indira Nederpelt
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Microneedle-based drug and vaccine delivery via nanoporous microneedle arrays
In the literature, several types of microneedles have been extensively described. However, porous microneedle arrays only received minimal attention. Hence, only little is known about drug delivery via these microneedles. However, porous microneedle arrays may have potential for future microneedle-based…