1,102 search results for “molecular genetica” in the Public website
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Chemical Biology Lecture: Functional supramolecular systems and materials
Lecture
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LED3 Lecture: Organoids to model human health and disease in vitro
Lecture
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Veni grants for 19 young Leiden researchers
Nineteen researchers who have recently been awarded their PhD are to receive a Veni grant of up to 250,000 euros. Science funding agency NWO has awarded a total of 158 Venis in this round; Leiden University's share of the awards is 12 percent.
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Making everything we know computer-readable
Data and information should be stored in a way that computers can understand, says Barend Mons, professor of Biosemantics at the Leiden University Medical Center and Chair of the High Level Expert Group for the European Open Science Cloud. We speak with him about FAIR data, knowlets and nanopublicat…
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YAL members
Read all about YAL membership and the members of the Young Academy Leiden.
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Hall of Fame 2020
In 2020, many of our staff and students have again won prestigious prizes and been awarded important research subsidies.
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2nd Munich-Leiden Virtual ChemBio Talks
Conference
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Training
As a PhD candidate, you are expected to follow certain courses and training programmes in the context of your training as a researcher. The courses and training programmes will help you conduct your research, write your dissertation, develop your career, and gain self-insight. The LACDR PhD training…
- Publication highlights
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ICM 2018 project results
Within the ICM 2018 project, Leiden University cooperated with 25 partner universities from 14 countries. In total, 97 mobilities were granted to this project - 65 mobilities were realised (some mobilities had to be ended prematurely due to covid-19, others were finished online).
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Better ligands for G Protein-Coupled Receptors
The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.
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CCLS Seminar
Lecture, Center of Computational Life Sciences
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Van Marum Colloquium: Visualizing electrified solid-liquid interfaces
Lecture
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In memoriam emeritus professor Jan Schmidt
On March 17, our dear colleague Jan Schmidt passed away after a fruitful and valuable life.
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White blood cells in transparent embryos
Leiden molecular cell biologists in the research group of Annemarie Meijer have discovered novel early macrophage-specific genes in zebrafish, including a signal transducer pivotal for the migration of macrophages in the innate immune response to bacterial infection. Their findings were published on…
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Vidi grants for nine Leiden researchers
From artificial intelligence to letters from the Dutch East Indies and from breast-cancer gene BRCA-1 to the collaboration between government and opposition: nine researchers from Leiden University have been awarded a Vidi grant for their research.
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New Medical Delta professors mean boost for health and technology research
Five of the new Medical Delta professors who now hold an appointment at multiple institutions are affiliated with Leiden University/LUMC. They are psychologist Andrea Evers and four LUMC professors.
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Spinoza Prize for Leiden statistician Aad van der Vaart
Aad van der Vaart, professor of stochastics at Leiden University, has been awarded the NWO Spinoza Prize for his groundbreaking research in statistics. Van der Vaart conducts fundamental research on models that can help, for instance, to identify genes that play a role in cancer.
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Medical Delta professor Marcel Reinders: ‘You need collaboration to make a real impact’
Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…
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MicroRNA: so small but so very important
The discovery in 2001 of the importance of microRNAs turned the world of molecular biology upside down. The small particles of RNA also attracted the attention of university lecturer Erno Vreugdenhil. Vreugdenhil: ‘Within five to ten years the first microRNA-directed medicines will come onto the mar…
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New technique offers chemists unprecedented control in drug research
Leiden chemists have developed a new technique with which they can determine the role of kinases – a group of proteins – in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer and rheumatoid arthritis. The team published the findings in the journal Nature…
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How do children's kidneys eliminate drugs?
What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…
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Immunologist Ton Schumacher wins NWO Stevin Prize
Ton Schumacher, professor by special appointment in Immunotechnology at the LUMC and group leader of Molecular Oncology and Immunology at the Netherlands Cancer Institute, has been awarded the NWO Stevin Prize. The Stevin Prize and the Spinoza Prize are the top scientific prizes in the Netherlands and…
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Discoverer of the Year, Best Dissertation and Education prize 2015
During the Faculty of Science New Year's reception, Daniël Rozen was named Discoverer of the year 2015. Nienke van der Marel and Koen van der Maaden both won the prize for the best dissertation and Jeroen van Smeden was named Best Teacher of 2015.
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Webb detects icy ingredients for making potential habitable worlds
An international team of astronomers, led by Will Rocha of Leiden Observatory, using the NASA/ESA/CSA James Webb Space Telescope have discovered that the key ingredients for making potentially habitable worlds are present in early-stage protostars, where planets have not yet formed.
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A game of Mastermind to unravel Alzheimer’s disease
In order to better understand the course of Alzheimer’s disease, Frédérique Kok believes that a strategic and structured approach is needed: the Mastermind research approach. With her LUF grant, Kok wants to generate high-quality data to build a mathematical model that can recognize the onset of the…
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Frederic Lens: building bridges in biodiversity research
Four green research institutes in Leiden are joining forces to integrate evolution and biodiversity research, at local and at the national level. Pivot in this collaboration is Frederic Lens.
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Robert Zwijnenberg: ‘Don’t just talk but dare to get your hands dirty’
Rob Zwijnenberg, Professor of Art and Science Interactions, uses daring experiments to get his students to think about social issues.
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30 years and Professor: the story of Changsheng Wu
The death of his grandfather in 1988 motivates Changsheng Wu to become a scientist. In 2016, he is awarded the C.J. Kok Jury Award for his thesis on novel antibiotics. Two years later, he will become a Professor at Shangdong University, at the age of 30 years.
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A lifeline for Leiden research – TB solution a step closer thanks to this Indonesian university
Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…
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Finding unique drug structures with artificial intelligence and chemistry
In the search for new medicines against diseases such as cancer, a Leiden team has developed a new workflow. This approach combines artificial intelligence (AI) with molecular modelling and is suitable for finding unknown and innovative drug structures, the researchers proved.
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Freon-40 may not be a useful marker of life
Observations made with the ALMA telescope in Chile and ESA’s Rosetta mission, have detected the faint molecular fingerprint of methyl chloride in gas, a chemical commonly produced by industrial biological processes on Earth, around both an infant star and a comet. Methyl chloride, also known as Freon-40,…
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Two Leiden astronomers awarded with prestigious IAU PhD Prize
Two Leiden astronomers will receive the prestigious IAU PhD Prize. Both Jorryt Mathee and Niels Ligterink of the Leiden Observatory won a prize. Scientific director Huub Röttgering: We are proud that this year two of our PhD students receive an IAU prize for the best thesis in their field of researc…
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The Erasmus+ grant opens doors
What is it like to participate in the Erasmus+ grant programme as a Master's student from Ukraine? Yevhenii Radchenko did an eight-month internship at Leiden University in 2018. Soon after, he returned as a PhD candidate. 'You have little to lose, but a lot to gain.'
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Vidi grants for eight researchers from Leiden University
Eight scientists from Leiden University have been awarded a grant by the Dutch Research Council (NWO). With this Vidi funding, the researchers can set up an innovative line of research and further expand their own research group over the next five years.
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DNA folded in compliant helix
In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…
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Graphene is a thoroughbred that has to be tamed
Electrons in graphene behave like light particles; they have no mass and can penetrate everything: very useful if you dream about nano-electronics. But you do have to channel them. Carlo Beenakker will be researching how. He has been awarded an ERC Advanced Grant of 1.5 million euro to carry out this…
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This is how a channel is formed between two organelles
The channel through which two cell components exchange material appears to form at the edge of their contact surface, and not in the middle. This was discovered by the Leiden physical chemists Jelger Risselada and Edgar Blokhuis together with researchers from the University of Lausanne in Switzerland.…
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‘Ultimately, the goal is to develop antibiotics for tuberculosis with a lower risk of resistance’
Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…
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Photosynthesis works with valves
Photosynthesis is the origin of life on earth, but it is a phenomenon that is still barely understood. Take, for example, the extremely efficient mechanism of electron transport. Leiden researchers demonstrate for the first time where one particular cause of this might be found.
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Xi’an Jiaotong University Day at Leiden University
16 April was a special day at the Faculty of Science. In honour of the collaborations with the Chinese partner university, it was declared Xi’an Jiaotong University Day.
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Urgent research projects funded by LUF
Misleading graphs, the erosion of democracy and the weakening of bones as a side-effect of medication. Researchers are starting work on these very topical problems, funded by subsidies from the Leiden University Fund awarded on 12 October.
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Scientists find strong evidence that wasting syndrome is the same for all organisms
An interdisciplinary team of Leiden researchers has discovered that wasting syndrome, a severe byproduct of tuberculosis, is the same for all humans and animals studied. The discovery offers new opportunities to investigate the still insufficiently understood condition. The scientists also developed…
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Artificial intelligence helps in the search for new antibiotics
With the search for new antibiotics becoming increasingly urgent, artificial intelligence offers valuable help. Smart software developed by Leiden PhD candidate Alexander Kloosterman searched genomes of bacteria and found clusters of DNA that code for proteins that have an antibiotic effect. ‘This new…
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Gravitation funding for five projects with Leiden researchers
The Advanced Nano-electrochemistry Institute Of the Netherlands (ANION) consortium will receive 23.6m euros in Gravitation funding for research on important electrochemical processes for energy transition. An additional four consortia with members from Leiden have also been awarded funding.
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Steering the immune system with liposomes
Liposomes – nano-sized spheres composed of fatty molecules – are very promising for vaccination. Bio-pharmaceutical scientist Naomi Benne discovered that the immune response in animal models can be steered by varying the charge of the liposomes. She obtained her PhD degree on 8 September for this research,…
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How a Spanish post-doc brings her expertise in chemistry to Leiden genetics
Having a bachelor's, a master's and a PhD in Chemistry, Elena Sánchez López shifted to a more biological field of research for her postdoc. She completed all her studies at the University of Alcala, in Spain, before applying for a LEaDing fellowship at Leiden University, a Marie Sklodowska-Curie Cofund…
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Leiden University involved in five Gravitation projects
Leiden University is involved in five new NWO Gravitation projects. Two relate to mental disorder and the remaining three to a healthy lifestyle, the combination of human and artificial intelligence, and the special relationship between plants and microbes.
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App helps students study better
Cramming from a book, making notes or learning summaries. In the past these were about the only ways to memorise your course material. But that has long since changed. Multimedia is the code word. But is it effective?