499 search results for “fmri use” in the Public website
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“DINO-Trial” evaluating the pharmacokinetics and pharmacodynamics of routinely used off-label drugs in premature neonates
Currently, more than 80% of drugs are used in an off-label manner in critically ill neonates.
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Can large carnivores like tigers survive in multiple use forests? A study in the buffer zone of Panna Tiger Reserve, India.
Which factors (human-dimension and carnivore related) shape human tolerance of large carnivore and large carnivore survival in multiple use forests?
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Understanding coercive nuclear reversal dynamics: A comparative case study of the US coercive diplomacy against the nuclear programs of Iran, Libya and South
What are the conditions under which coercive diplomacy can compel a State to abandon its controversial nuclear (weapons) program? Based on the experience of the US coercive diplomacy against the nuclear programs of three countries, namely Iran, Libya and South Africa, Jean Yves Ndzana’s PhD research…
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Making educational reforms practical for teachers: using a modular, success-oriented approach to make a context-based educational reform practical
For a successful implementation of an educational reform, teachers need to regard the proposal as being practical. I used a modular, success-oriented approach to make a context-based reform practical for implemtentation in Duthc biology education. educational reform, modular, teachers, biology, success-oriented,…
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Probabilities for Highly Activated Reaction of Polyatomic Molecules on Surfaces Using a High-Dimensional Neural Network Potential: CHD3 + Cu(111)
An accurate description of reactive scattering of molecules on metal surfaces often requires the modeling of energy transfer between the molecule and the surface phonons. Although ab initio molecular dynamics (AIMD) can describe this energy transfer, AIMD is at present untractable for reactions with…
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active tubular secretion in predicting renal clearance in children using population pharmacokinetic and physiology based pharmacokinetic modeling
In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.
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Understanding the #plandemic: Core framings on Twitter and what this tells us about countering online far right COVID-19 conspiracies
This paper examines the need and possibility for developing online resilience-based approaches in response to COVID-19 vaccine conspiracies, often linked to the far right.
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Using Rhetorical Structure Theory for contrastive analysis at the micro and macro levels of discourse: An investigation of Japanese EFL learners’
On March 12th, Jonathan Brown succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Jonathan on this great result.
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Advancing the European Multilingual Experience
The project Advancing The European Multilingual Experience (AThEME) studied multilingualism in Europe by incorporating and combining linguistic, cognitive and sociological perspectives.
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‘Do Not Say They Are Dead’: The Political Use of Mystical and Religious Concepts in the Persian Poetry of the Iran-Iraq War (1980-88)
The chief aim of this study is to explore how classical Persian poetry and the Persian mysticism that is interwoven with the poetry have been used in the new politics of the Islamic Republic of Iran, especially during the Iran-Iraq war.
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Monsters in the Deep: Using simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
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of darkness: constraining the nature and properties of dark matter using the stellar kinematics in the centres of ultra-faint dwarf galaxies
Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.
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What makes us ill?
Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…
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What Spinoza winners Ellemers, Sluiter and Franx will do with €2.5 million
On Monday 27 September 2010 Spinoza prize winners Naomi Ellemers, Ineke Sluiter, Marijn Franx (Leiden) and Piet Gros (Utrecht) announced their plans for their €2.5 million prize money. This was during the official ceremony in The Hague, at which the outgoing Secretary of State for Education, Culture…
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Use of nouns delays speech
Why do we sometimes speak more slowly or more rapidly, and why do we sometimes have a longer pause between uttering particular words? This has to do with whether you are about to use a noun or a verb. This is the finding from research by an international team led by linguist Frank Seifart from the University…
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Twitter use helps predict flooding
Heavy rainfall can cause streets to flood and basements and tunnels to overflow. Jan van Rijn investigated, together with Christiaan Lamers (formerly of Leiden University) and Ton Beenen (STOWA, RIONED), how data science can help to predict which areas are at greater risk of flooding. Van Rijn presented…
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'Using mediation in cultural conflicts'
Insults have a stronger effect on people from honour cultures because their honour is at stake. Escalations can be prevented if their sense of honour is left intact or if the perpetrator expresses sincere regret Leiden psychologist Said Shafa has found.
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Switching lifestyles using hormones
Vicencio Oostra, who defended his PhD-thesis at the IBL successfully in June 2013, published new insights into the hormonal regulation of butterfly responses to fluctuating environments.
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New technique makes it easier to determine how our ancestors used fire
The use of fire can tell us a lot about human evolution. Archaeologist Femke Reidsma has developed a more accurate technique to identify how our ancestors used fire. Existing archaeological studies will need to be revised. Reidsma’s study was published in Nature Scientific Reports on 2 November.
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Bridging the unbridgeable: linguists, prescriptivists and the general public
This project seeks to close the gap between the three main players in the field of prescriptivism: the linguists themselves, the prescriptivists (as writers of usage guides) and those who depend upon such manuals.
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Using DNA to look for fish species
Researchers from Biomon have used DNA-techniques to find 40 different species of fish in the river Dommel. This technique is capable of detecting more species than conventional methods of measuring.
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Placebo research: Pharmacological conditioning
The major aim is to examine the potential of learning the body to produce a similar physiological (autonomic, neuroendocrine, or immune) and physical (e.g., desensitization of persistent physical symptoms) response to placebo medication than to active medication (pharmacological conditioning). If proven…
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Data Science
The ability to collect and interpret huge quantities of data has become indispensable to society and academia. Leiden University is a knowledge and expertise centre for data science that places the emphasis on interdisciplinary collaboration and innovation.
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ERC Consolidator Grant for Eveline Crone
Eveline Crone surmises that adolescence also has a positive effect on social development. She believes, for example, that it is in adolescence that young people learn the skills of cooperation, sharing and helpfulness. She will be researching this hypothesis in the coming period with an ERC Consolidator…
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Survey: use digitale collections Utrecht University Library
Utrecht University Library invites researchers, students and other users of their digital collections to complete a survey about this: what material are you looking for (and can you find it), what functionalities do you use, what do you like and what could be improved? The library uses the suggestions…
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Distinguishing differences in dementia using brain scans
Neuroscientist Anne Hafkemeijer is able to distinguish two different forms of dementia using advanced imaging techniques. This is the first step towards early recognition of dementia in patients on the basis of brain networks. PhD defence 26 May.
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What makes us human? Or modern human?
Two Vidi subsidies for Faculty of Archaeology.
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DWDD University uses Leiden Physics experiments
In the latest episode of DWDD University on 'Light', Prof. Robbert Dijkgraaf used a number of experiments from the Leiden Physics Practicum Lab. He showed why the sky is blue, that light is a wave phenomenon, how magnetism and electricity are connected and that white light consists of all colors of…
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Vertebrate genome sequencing using nanopore technology
An international team from the Netherlands, France, Norway and Austria demonstrate how new sequencing technologies can be used to efficiently generate the genome, DNA, sequence of an endangered animal, the European Eel.
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Songbird passes grammar test using mnemonics
Songbirds apparently use mnemonics rather than more complex grammatical rules to recognise structures in which they have been trained. Leiden behavioural biologist Caroline van Heijningen published an article on this subject on Tuesday 17 November in PNAS.
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Using sensors to measure playground dynamics
Free playtime and physical play are of great importance to children's social development. That is the main conclusion of innovative research by developmental psychologists and computer scientists from Leiden University.
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Free symposium reveals surprising uses of AI
Artificial Intelligence (AI) can help humans in many different ways: from customised medicine and self-driving cars to preserving our cultural heritage. On 4 April academics from Leiden will talk about the achievements and opportunities of AI. A research dossier on AI is also online now, which looks…
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New Alzheimer’s research method uses muons
Alzheimer’s disease is the most common form of dementia. This makes fundamental research on the precise cause of the illness of vital importance. One of the possible suspects is a certain protein filled with iron. Leiden physicist Lucia Bossoni (LION/LUMC) has now developed a new way of investigating…
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Designing better catalysts using simple chemical concepts
An international team of researchers, including Federico Calle-Vallejo of Leiden University’s Institute of Chemistry, have taken the atomic-scale design of catalysts to the next level. Their research contributes to the quest for a method to generate or store energy more efficiently. The report is published…
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Using fungi to produce renewable energy
Ebru Alazi ‘hacked’ an enzyme-producing system in the fungus Aspergillus niger in order to produce renewable energy more easily. She manipulated the fungus, making it produce more pectinases: enzymes mainly used in the food industry and in the production of renewable energy, such as biofuels. Promotion…
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Studying abstract mathematical equations using tangible surfaces
On January 5, Rosa Winter will obtain her doctorate in arithmetic geometry. She researched solutions of equations that define so-called ‘del Pezzo surfaces’. ‘I like geometry because I can imagine and draw the shapes and objects,’ says Winter. ‘That makes abstract mathematics feel more tangible.’
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Leiden political scientists advise US diplomats
Leiden political scientists Yvonne Kleistra and Niels van Willigen have advised the United States State Department as to how to evaluate its foreign policy. Point of departure was a scientific model that Kleistra and Van Willigen have developed on the basis of their work for the Dutch Foreign Affairs…
- Social and Behavioural Sciences
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Updated MRI scanner ready for use
The updated MRI scanner at the Leiden Institute for Brain and Cognition (LIBC) will become operational on 29 September. The new version is faster and better than the current model.
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tot Delaware: How empirical legal research on valuation biases was used in a US courtroom
In a Leiden Law Blog, lab member Niek Strohmaier and Marc Broekema describe how their research on valuation biases was used by the Delaware Court of Chancery in a recent valuation dispute involving telecom giant AT&T.
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‘We should help nature to help us’
Biodiversity and healthy ecosystems continue to decline in Europe, which has serious consequences for human welfare. These are findings of a report that was formally approved by delegates from 127 governments during a UN plenary in Medellin, Colombia. Leiden researcher Alexander van Oudenhoven was one…
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Daredevil behaviour of young people due to active reward centre in the brain
Young people tend to take more risks than children or adults. This trend is related to the reward centre in the brain, which is much more active when they are rewarded, PhD candidate Barbara Braams discovered. Personality, testosterone levels and social context also play a role in risk-taking.
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Positive feedback activates adolescent brain
Children and adolescents really do use their ‘smart’ brain areas. This has been confirmed by an extensive and long-running study of the brain carried out by developmental psychologist Sabine Peters . Her findings can have important consequences for education. PhD defence 27 January.
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The ancient Egyptians were just like us
The people who lived in Saqqara, City of the Dead in Egypt, died thousands of years ago, but they are not all that different from us. This is what a study by the National Museum of Antiquities in Leiden, The Netherlands concludes. If you wanted to prove that you had good taste in ancient Egypt then…
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Sensing drug responses of single cells using optical tweezers
Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.
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Single-use water bottles? Not on our watch.
We, as LUGO, believe that with simple everyday actions we can prevent large amounts of single-use plastic water bottles from entering our oceans.
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Burning the land
A global synthesis of the extent, diversity and patterns in off-site fire use by historically documented and current hunter-gatherers with the remit of this study in the deeper past.
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Terrorists who use the internet are less successful
There is too much focus on online radicalisation, says Joe Whittaker, when this is just one of the factors that make someone become a terrorist. In fact, Whittaker’s research shows that terrorists who use the internet are less successful in achieving their goal than those who stay offline. He will defend…
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The Guardian on revealing old texts using X-rays
Scientists from Leiden and Delft recently discovered old texts using X-ray radiation. The subject was reported in the English newspaper The Guardian.
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Nathaniel Martin: why won’t antibiotics cure us anymore?
Current means of fighting bacteria are no longer as good as they used to be because of antibiotic resistance. These days, people are dying from bacterial infections that could have been cured fifty years ago.