1,102 search results for “molecular genetica” in the Public website
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Vici grants for four Leiden researchers
Four Leiden researchers have been awarded a prestigious Vici grant by the Netherlands Organisation for Academic Research (NWO).
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Fifty Shades of Stress
The challenge: Building a tool to detect chemical compounds that individually cause non-lethal stress to bacteria, but that are lethal in combination. A team of thirteen Leiden students are taking up this challenge in the annual ‘international Genetically Engineered Machine’ (iGEM) competition for applications…
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Cross-talk between stagnation points in flow and orientation
Publication in Proceedings of the National Academy of Sciences.
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New carbon membrane generates a hundred times more power
Leiden chemists have created a new ultrathin membrane only one molecule thick. The membrane can produce a hundred times more power from seawater than the best membranes used today. The researchers have published their findings in Nature Nanotechnology.
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Public honour for Professor Bert Meijer, member of Board of Governors
On 28 February, Professor E.W. Meijer, member of Leiden University’s Board of Governors, was appointed Commander in the Order of the Dutch Lion.
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Ten years of Life Science and Technology
On September 9th 2009, the study Life Science and Technology (LS&T) celebrates its 10th anniversary. In 1999, a group of enthusiastic pioneers within the Technical University Delft (TUD) and Leiden University (LU) founded a novel study based on the biotechnological expertise of research institutes within…
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Two young female Leiden researchers join Oncode
The Oncode Institute is a new international network organisation that focuses on making sure that new scientific findings on cancer are implemented in patients as rapidly as possible. Two young female researchers at Leiden University have been selected to join Oncode: Laura Heiman (Leiden Academic…
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New Directors of Education IBL
Remko Offringa, Associate Professor in Plant Developmental Genetics, and Associate Professor in Molecular Microbiology Arthur Ram both have been appointed as the new Directors of Education at the IBL. Offringa in the role as Director of Education for the Master program and Ram as Director for the Bachelor…
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4 Vici awards for Leiden researchers
Chemist Alexander Kros and astronomer Joop Schaye are two of the four Leiden researchers who have been awarded a Vici as part of NWO's Innovation Research Incentives scheme. They each have 1.5 million euros to set up a research group and employ PhD candidates.
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New project funded to study Alzheimer's disease
Researchers from Leiden University will develop a new approach to study the biomarkers of Alzeimer’s disease. This approach focusses on the molecular messengers of the cells. The project, led by Thomas Hankemeier and coordinated by Yuliya Shakalisava (Leiden Academic Centre for Drug Research, LACDR),…
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Consultancy and Innovation
Are you dealing with an educational challenge or would like to explore innovation opportunities? We actively ideate, design, prototype, build, test real-world solutions to transform theoretical ideas into tangible solutions to enhance the educational landscape for the benefit of your students.
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Layers of dental tartar
Bacteria in the teeth tell us a lot about nutrition and disease in our ancestors. It also tells us more about the immune system. This provides clues for treating modern diseases and allergies. For a long time archaeologists were irritated by tartar on the teeth of excavated skulls. They thought that…
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Biomolecular analyses of skeletal remains in the circum-Caribbean across the historical divide (A.D. 1000-1800)
As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.
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Research
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Postdoctoral researcher in Supramolecular Chemistry
Science, Leiden Institute of Chemistry (LIC)
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Chemistry between stars and planets
In the large gas clouds between the stars, chemical reactions take place under extreme conditions, giving rise to both small molecules, such as water and common salt, as well as large complex molecules that can serve as the building blocks of life. This is known as astrochemistry and it is something…
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Gerard van Westen: 'Our model predicts what candidate drugs do in your body'
He’s a fast and animated speaker, which is only logical because Gerard van Westen is driving an express train. His destination? A virtual human, consisting of algorithms that predict what an administered substance will do in the body. The train is already a long way down the line and the pharmaceutical…
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Glucocorticoids in zebrafish
A novel in vivo model system for studies on glucocorticoid resistance
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Allosteric Modulation
Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory sites distinct from the active site on the protein, resulting in conformational changes that may profoundly influence protein function. This concept…
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Testimonials
Read about experiences of former students.
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Taking care of your health
Health is a wonderful gift, both for humans and for society. If we are able to prevent both physical and mental illnesses, we can spare a lot of suffering and fight rising health costs. Social scientists and physicians in Leiden are working closely together to conduct research on the human mental, behavioural…
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Animal sciences and health
In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.
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Using zebrafish to target the Achilles’ heel of cancer
Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.
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Key publications
Key research articles and book chapters of the Chromatin group.
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Vascular and Regenerative Medicine
Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…
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Environmental and genetic drivers of wood and lignin formation in flowering plants
In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.
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Awards and Grants 2022
An overview of awards and prizes granted to our staff and students in 2022, as well as special appointments at Leiden University and other institutions.
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Quantum dynamics of H2 on metal surfaces: researching the role of surface atoms
This research focuses on the (Quantum) Dynamics (QD) of the reactive scattering of H2 from metal surfaces.
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Chemical Probe Facility
The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…
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Inverse Agonism and Constitutive Activity
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Urban ecology and avian acoustics: Function and evolution of birdsong in a changing world
Birds sing to be heard, but how do they cope with increasing noise levels? Which species persist in cities and why? And do they thrive or suffer in the urban soundscape?
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Invaluable bees and nature’s other services
We depend on nature for so many things: from clean water, wood and food to carbon absorption, water purification and coastal protection, as well as for relaxation, inspiration and identity. Nevertheless, our modern world putting increasing pressure on these ecosystem services. Leiden researchers investigate…
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Image-based Computational Biology
In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…
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Postdoc: Reactive scattering with electronic friction
Science, Leiden Institute of Chemistry (LIC)
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About Leiden University - Working at Leiden University
As far back as 1575, Leiden University researchers have been leaving their mark on the world.
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Tuition fees
Your tuition fee depends on a number of factors, such as your nationality and your previous Dutch higher-education qualifications.
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Robert Smit receives his PhD with distinction. ‘I am happy to be back in the lab’
An all-optical transistor, a molecule-sized sensor and a new kind of single-photon source for quantum communication. All dreamed applications of fundamental physics that are one step closer thanks to Robert Smit. On 12 June, he defended his PhD thesis with distinction.
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Honorary doctorate for LUMC Dean Pancras Hogendoorn
Pancras Hogendoorn, Professor of Pathology and Dean of the Leiden University Medical Center (LUMC), received an honorary doctorate from Semmelweis University in Budapest on Friday 8 October 2019.
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800 year old mystery of ancient bone disease solved
Scientific research at the molecular level on a collection of medieval skeletons from Norton Priory in Cheshire, United Kingdom, could help rewrite history after revealing they were affected by an unusual ancient form of the bone disorder, Paget’s disease. Osteoarchaeologist Carla Burrell, attached…
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Subsidies for high-grade research facilities
Three projects with Leiden researchers are to receive a subsidy from NWO for the construction or renovation of large-scale research facilities. They will be working on electron microscopy, an X-omics initiative and an X-ray telescope. The projects are part of the National Roadmap for Large-Scale Scientific…
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It’s all about the cell wall for brand-new professor Dennis Claessen
Dennis Claessen has been appointed professor of Molecular Microbiology at the Institute of Biology Leiden. With his teaching and research on the cell wall, the professor wants to establish applications in the industry and the medical sector.
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Scouring the brain for causes of psychiatric illnesses
What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’
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From droplets in the freezer to the inception of a potent new antibiotic
What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…
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Better and faster ways of searching for antibiotics
Antibiotic-resistant bacteria are a major problem worldwide. Molecular biologist Changsheng Wu explored innovative methods of developing new antibiotics more simply and more easily. He also discovered a new type of antibiotic.
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Seven new Medical Delta professors
Medical Delta has appointed seven professors who will bridge the medical worlds of Leiden, Delft and Rotterdam.
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Teaching synthetic molecules how to communicate
Although Sander Wezenberg just started working in Leiden in March this year, he already managed to win a Vidi grant from NWO. Inspired by nature, Wezenberg wants to bring synthetic molecules to life and teach them to communicate. But who exactly is Wezenberg and what drives him?
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EU awards COFUND grant for 18 Post-docs working on the Origin and Evolution of Life
The European Union has awarded a COFUND grant to a consortium of researchers from the universities of Groningen, Leiden and Eindhoven for a collective fellowship programme called ‘oLife’. The 6 M€ programme, which is co-financed by the participating universities, will recruit and train 18 post-doctoral…
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NWO grants two IBL-proposals by interdisciplinary research consortia
Recently, NWO has decided to grant two interdisciplinary research proposals for national and international consortia submitted by researchers from the Institute of Biology Leiden. One of the proposals is led by Prof. dr. Ariane Briegel, the other one by dr. Remko Offringa.
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Nanoparticles can aid in stroke therapy
Tiny selenium particles could have a therapeutic effect on ischemic brain strokes by promoting the recovery of brain damage. Pharmacologists, including Alireza Mashaghi from the Leiden Academic Centre for Drug Research discovered that selenium nanoparticles inhibit molecular mechanisms that are responsible…