434 search results for “cell chemistry” in the Staff website
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A unique defence: Bacteria lose cell wall in the presence of virus
Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…
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First patient in the Netherlands successfully treated with stem cell gene therapy
Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…
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In memoriam Harold V.J. Linnartz 1965 – 2023: Unlocking the Chemistry of the Heavens
With great sadness we share the news that Prof. Harold Linnartz passed away suddenly and unexpectedly on Sunday 31 December 2023. We are all in shock, and our thoughts are with his wife and children, other family, and friends. Harold was at the heart of our institute, as a researcher, as a supervisor,…
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Caught in living cells: how bacteria regulate their genes to defend themselves
For the first time, it was shown in living cells how the bacterium E. coli regulates genes that help it survive in a new environment. Biochemist Fatema Zahra Rashid managed to do this using a technique she fine-tuned. Her research into changes in 3-dimensional chromosome structure offers clues for ways…
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EIC Pathfinder Challenge grant for research into autoreactive B cells in cardiovascular disease
At the division of BioTherapeutics, Amanda Foks, Bram Slütter and Ilze Bot have obtained a €4 million research grant from the HORIZON 2022 EIC Pathfinder Challenge “Cardiogenomics”, entitled “B-specific: B-cell related gene and protein markers with prognostic and therapeutic value for CVD”.
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‘I am curious and full of passion for understanding molecular chemistry’
Since May, Assistant professor BioTherapeutics Lu Su works in our faculty. Although she is still young, she already worked in many different fields and co-operated on two publications in big scientific journals. How did she become so successful and what motivates her to keep researching the possibilities…
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Young Hae Choi
Science
y.h.choi@biology.leidenuniv.nl | +31 71 527 4510
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Serkan Aslan
Science
s.aslan@lacdr.leidenuniv.nl | +31 71 527 5919
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Physics in the picture: cancer cells as an explosion of fireworks
When you think of physics, do you think only of complicated formulas? You’re not the only one. Therefore, every year, the Leiden Insitute of Physics organises the LION Image Award to show another side of physics: beautiful images about intriguing science. The winner of the 2022 photo competition captured…
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Jorrit Smit
Faculteit der Sociale Wetenschappen
j.p.smit@cwts.leidenuniv.nl | +31 71 527 2727
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Elmer Maurits
Science
e.maurits@lic.leidenuniv.nl | +31 71 527 2727
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Anthe Janssen
Science
a.p.a.janssen@lic.leidenuniv.nl | +31 71 527 4362
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Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
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Joey Zuijdervelt
Science
j.l.zuijdervelt@lacdr.leidenuniv.nl | +31 71 527 6227
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Remko Offringa
Science
r.offringa@biology.leidenuniv.nl | +31 71 527 5097
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Innovating Cell Pharmacy with stem cells
Lecture
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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Sebastian Pomplun
Science
s.j.pomplun@lacdr.leidenuniv.nl | +31 71 527 4651
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Sander Wezenberg
Science
s.j.wezenberg@lic.leidenuniv.nl | +31 71 527 4541
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AI in Chemistry: minisymposium
Conference
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Cell Pharmacy
Inaugural lecture
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Nobel Prize winner visited Leiden: 'We have hosted a scientific rockstar'
On 28 September the famous chemists Carolyn Bertozzi visited Leiden University to speak at the LED3 seminar. Just one week later, she was announced winner the 2022 Nobel Prize in Chemistry. Leiden chemists Sebastian Pomplun and Hermen Overkleeft are fan: ‘We are extremely honoured to have hosted this…
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Four NWO Open Competition grants for Leiden researchers
Four researchers from Leiden University have been awarded NWO Open Competition grants in the Science domain. This is for research into subjects such as immune cells in tumours, antibiotic resistance and magnetic semiconductors.
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Erik van Geest
Science
e.p.van.geest@lic.leidenuniv.nl | +31 71 527 2727
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Sylvestre Bonnet
Science
bonnet@chem.leidenuniv.nl | +31 71 527 4260
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Thomas Hankemeier
Science
hankemeier@lacdr.leidenuniv.nl | +31 71 527 4226
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The energy transition under the nanoscope: Gravitation funding for ANION project
Bringing together chemists and physicists to thoroughly investigate how electrochemical processes work on the smallest scale. That is the goal of the new Advanced Nano-electrochemistry Institute of the Netherlands, or ANION for short. The consortium receives a Gravitation funding of 23.6 million euros…
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Bas ter Braak
Science
s.j.ter.braak@lacdr.leidenuniv.nl | +31 71 527 2727
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Herman Spaink
Science
h.p.spaink@biology.leidenuniv.nl | +31 71 527 5055
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Investigating inflammation: new leads for treating atherosclerosis
How do you detect people at high risk of heart attacks and strokes? And how can we improve the treatment of atherosclerosis? These are the questions that keep LACDR researcher Marie Depuydt busy. She is investigating the immune cells that contribute to the worsening of atherosclerosis. ‘It's a challenging…
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Unravelling cell fate decisions through single cell methods and mathematical models
PhD defence
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Forces and Symmetries in Cells and Tissues
PhD defence
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Structure-reactivity relationships in glycosylation chemistry
PhD defence
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Bioorthogonal chemistry to unveil antigen processing events
PhD defence
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Mechanisms and consequences of horizontal gene transfer in cell wall- deficient cells of Kitasatospora viridifaciens
PhD defence
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Peter Bouwman
Science
r.j.p.bouwman@lacdr.leidenuniv.nl | +31 71 527 6105
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New potential drug suppresses chemotherapy induced neuropathic pain
Oncode Investigator Mario van der Stelt and his colleagues have discovered a new potential drug that suppresses chemotherapy induced neuropathic pain.
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Applications of multisource data-based dynamic modeling to cell-cell signaling and infectious disease spreading
PhD defence
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The role of bubble formation in sustainable hydrogen production
The sustainable production of hydrogen could potentially be made more efficient by adding a cleverly chosen salt to the process. Researchers at the Leiden Institute of Chemistry (LIC), in collaboration with physicists at the University of Twente, have discovered that the type of salt present in the…
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Click to Release for Immunce Cell Activation
PhD defence
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Single-cell immune profiling of atherosclerosis
PhD defence
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Curing diseases with lab-grown organs
Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…
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The molecular secrets of medicinal cannabis
Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…
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Search and Rescue: Tackling antibiotic resistance with chemistry
PhD defence
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A promising marriage between Siemens and Leiden spin-off Culgi
Siemens recently took over the Leiden software company Culgi, founded by professor and inventor J.G.E.M. (Hans) Fraaije. We spoke to him about the algorithm that made him successful, the role of a university in our society and his ambitions at Siemens. ‘I was looking for Siemens, and they were looking…
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A cycle of life of T cell activation
Inaugural lecture
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…
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Joost Willemse
Science
jwillemse@biology.leidenuniv.nl | +31 71 527 4986
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Bob van de Water
Science
water_b@lacdr.leidenuniv.nl | +31 71 527 6223
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Functional fluorescent materials and migration dynamics of neural progenitor cells
PhD defence