Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

The work presented in this thesis addresses the role of the locus coeruleus (LC) - norepinephrine (NE) system in various aspects of human cognition, and the modulation of brain state.

The writings of Walter Benjamin (1892-1940) are famously and purposely marked by fragmentariness. Paradoxically, a central aim of his work was to connect: all his life he sought to further the integration of scholarship in the humanities which, he believed, had too long suffered from the prevalence…

On 18 March 2020, Hoko Horii defended her thesis ‘Child Marriage as a Choice. Rethinking agency in international human rights’. The doctoral research was supervised by prof. A.W. Bedner and prof. G.A. van Klinken.

Promotores: Prof.dr. J. Schaye & Prof.dr. C. Steidel (California Institute of Technology)

Promotor: Prof.dr. E.F. Smets

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

This project investigates the well-preserved agricultural terraces of the Inn valley and the evolution of resource use in the inner Alps.

The transition from single cells to multicellular organisms was a key step in evolution. Researchers from Leiden and Amsterdam developed a mathematical model that explains how this transition may have come about. They suspect cooperating cells may correct each other’s mistakes. Publication in eLife…

The routine assumption that Upper Palaeolithic early modern humans in Europe were regular fire users who produced fire at will has never been tested against the archaeological record. Utilizing literature, database and microwear analytical approaches, this project seeks to establish the role and forms…

The central question in this book is whether there is a human right to family unification.

How are the epidermal lipid pathways involved in health and disease.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

The research that is united in the Liveable Planet programme, touches upon a wide range of aspects of human life. The goal is to deepen and expand the scope and to connect more researchers. The following case studies are examples of current research projects.

Investigating epistemic and ethical practices in medical experimentation on humans in the colonial period in Southeast Asia.

Venomous animals serve as models for a variety of mimicry types. Michael Richardson (IBL) and his international colleagues find that a group of fishes (called fangblennies) evolved venom after the origin of their venom-delivering fangs.

BACKGROUND: Explant human skin equivalents (Ex-HSEs) can be generated by placing a 4mm skin biopsy onto a dermal equivalent. The keratinocytes migrate from the biopsy onto the dermal equivalent, differentiate and form the epidermis of 1(st) generation Ex-HSEs. This is especially suitable for the expansion…

Radio jets are important to the evoultion of galaxies. However, it is still not fully understood how a radio jet can be triggered.

How do nonmotile microbes leverage communal motility?

How do balanced lethal systems originate and persist in nature?

The high prevalence of pure red cell aplasia in Thailand has been associated with the sharp increase in number of recombinant human erythropoietin (rhEPO) copy products, based on a classical generic regulatory pathway, which have entered the market.

What is the population size/structure and distribution of tiger and leopard inside the Bardia National Park (BNP) compared with the population outside? What is the movement and home range and conflict pattern in time and space of tigers and leopards inside the BNP compared with outside? What constitutes…

The main purpose of DNAmarkerpoint is to better understand the ecology, evolution and biodiversity through the study of ancient- and modern DNA.

Supervisor: Natalia Ortiz Zacarías

The Faculty of Archaeology's own home-grown journal Inter-Section has released a new volume. Inter-Section offers students and PhD candidates the unique chance to publish in a peer-reviewed journal. The new volume focuses on the materials that shape our world.

PhD defence

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

This dissertation studies the Asymptotics of Bayesian nonparametric inference for Gaussian linear models.

Taxonomy as a science has accumulated data and knowledge for more than 250 years.

Climate change is one of the largest challenges faced by humanity. To combat this research into alternatives to fossil fuels is ongoing. Dihydrogen is considered a good alternative fuel, since its burning only forms water.

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond

The aim of the research project is to get insight in the biostratigraphical age and the palaeoecological setting of the Schöningen sites and hominin behavior and subsistence during the late Lower Palaeolithic.

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Promotor: C.J. ten Cate

Study Archaeology at Leiden University. Learn about a full range of theoretical, analytical and field methods from some of the world's leading archaeological researchers.

What is the population size and social structure in time and space? What is the lion diet and food preference in time and space? What is the home range (MCP and Kernel) and movement in time and space? What are human – lion conflict and responses of lions to traditional herding in time and space? What…