894 search results for “molecular genetica” in the Public website
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Leindert Boogaard
Science
boogaard@strw.leidenuniv.nl | +31 71 527 2727
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Bob van de Water
Science
water_b@lacdr.leidenuniv.nl | +31 71 527 6223
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Colloquium: Polymeric heterogeneous water oxidation catalysts with molecular metal sites
Lecture
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Admission requirements
To be eligible for Chemistry at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for Molecular Genetics and Biotechnology at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for Molecular, Cellular and Organismal Biology at Leiden University, you must meet the following admission requirements.
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Cuba
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Centre with University of Havana.
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Dissociative chemisorption on transition metal surfaces
The dissociative chemisorption of a molecule on a transition metal surface represents a rate-limiting step in many heterogeneously catalyzed processes, whereby most chemicals are made. In spite of the importance of this reaction, an accurate first principles approach to modeling it does not yet exist.…
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Science
The Faculty of Science
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Making fuels from sunlight and CO2
Plants could be regarded as small chemical factories, which produce chemical substances via photosynthesis. If we can imitate photosynthesis in an artificial system, we can make clean fuels and materials out of sunlight and CO2. Huub de Groot is very close to designing a system of this kind.
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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Career prospects
With a MSc in LST you are well prepared for a wide range of career opportunities. Life Science research and business is one of the fastest growing economic activities worldwide.
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Sustainable futures
How can we organise society so as to keep our planet habitable for us and for all other life forms around us? To answer this question, Leiden researchers collaborate across disciplines, from biology to data science, and from environmental economy to archaeology.
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Microplastics in artery plaque linked with higher risk of heart attack, stroke and death
You can't see them with the naked eye, but they are highly likely to pose a threat to our health: microplastics. These tiny plastic particles are present everywhere in the environment, including within our bodies. On science platform The Conversation molecular biologist Meiru Wang offers valuable insights…
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Elucidation of the molecular alterations underlying aging-associated muscle wasting by applying multi-omics
PhD defence
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Molecular imaging of pancreatic and rectal cancer - Towards optimized detection and response prediction
PhD defence
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SUMO unchained; molecular mechanisms of ubiquitin-like signal transduction in cell cycle progression
PhD defence
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About
The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology. We are part of the Faculty of Science at Leiden University.
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Research
Research at the BIOSYN group is comprised of the following research themes:
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Supramolecular materials: from biosensors to cell delivery devices
The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…
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Plant Sciences
The mission of the Plant Sciences cluster is to contribute to the sustainable production of high-quality crops, flowers and high-value bio-based products, and to contribute to the maintenance and restoration of biodiversity in natural ecosystems. This is realised by generating fundamental knowledge…
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Modeling energy conversion dynamics at interfaces
Chemical reactions go hand-in-hand with an energy exchange with the environment in which they take place. Surfaces offer a variety of energy dissipation channels, constituted by the nuclear and electronic degrees of freedom of the atoms at the interface. Aiming at an improved future harvesting of energy,…
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Glucocorticoid modulation of the immune response
Unraveling the immune-suppressive actions of drugs like prednisone.
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UM Cure 2020: New therapies for uveal melanoma
Can we bring novel treatment options to the clinic for UM patients with liver metastases?
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Hit Discovery
The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.
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Gas-surface reaction dynamics and surface science
The local ordering of atoms at the surface of a metallic particle determines its catalytic activity and selectivity. As energy systems of the future will be based on efficient catalytic conversion of small molecules in closed cycles, we study how structural effects of catalysts can be used to our ad…
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Research in Physics, Quantum Matter and Optics (MSc)
The master’s specialisation Research in Physics, Quantum Matter and Optics at Leiden University offers a thorough experience on the front line of physics research with a practical training of communicative and computer skills. The programme focuses on Condensed Matter problems, such as Molecular Electronics,…
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Metals in Catalysis, Biomimetics & Inorganic Materials
Coordination chemistry is the chemistry of metal atoms
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Sustainability courses and programmes
Leiden University offers its students a wide range of bachelor's, master's and minors that explore sustainability or climate. Here, you find an overview of those programmes in the academic year 2020-2021.
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Food
The research within the Food research programme at CML focuses on a transition towards sustainable food production and consumption systems. We investigate from a very small to a very large scale, at a local, national or international level. We do so by researching for example molecular tools, food systems,…
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The scientists behind LED3
LED3 is the combined effort of three excellent institutes of Leiden University. Through joined hands, we are able to give rise to a more effective early drug discovery pipeline. Let us briefly introduce the three institutes.
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Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Collaborations
Ecotox is located in an ambitious surrounding at the Leiden University. It is an initiative of both institutes Institute of Environmental Sciences (CML) and Institute of Biology Leiden (IBL).
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Medical Systems Biophysics and Bioengineering
The ambition of the Medical Systems Biophysics and Bioengineering group led by Alireza Mashaghi is to develop and use physics and engineering concepts and tools for pathophysiology, diagnostics and therapy.
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Specificity and side-effects of mutagenesis by CRISPR/Cas9 -induced breaks in plants
Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?
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Supramolecular polymer materials for biomedical applications and diagnostics
Self-assembly is an abundant process in nature and is vital to many processes in living organisms.
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Pascal chair at LIACS
The Leiden Institute of Advanced Computer Science (LIACS) of Leiden University proudly establishes the Blaise Pascal chair. The chair applies for one year and is meant to strengthen the cooperation of the Leiden computer science research with foreign institutes.
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Research Schools
Many researchers of the Faculty of Science are members of a research school related to their area of expertise. Research schools aim at collaboration of researchers from different faculties in the same university (interfaculty schools) or in different universities (interuniversity schools).
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Tracing the journey of the sun and the solar siblings through the Milky Way
Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown
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Structural and functional analysis of proteins involved in natural product biosynthesis and morphological differentiation in Streptomyces
Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.
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A study on PsbS and its role as a pH sensor
Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.
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Systems dermatology of inflammatory diseases
Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…
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Accurate Probabilities for Highly Activated Reaction of Polyatomic Molecules on Surfaces Using a High-Dimensional Neural Network Potential: CHD3
An accurate description of reactive scattering of molecules on metal surfaces often requires the modeling of energy transfer between the molecule and the surface phonons. Although ab initio molecular dynamics (AIMD) can describe this energy transfer, AIMD is at present untractable for reactions with…
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Zipping into Fusion
Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros
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Multiple star formation: chemistry, physics and coevality
Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.
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Personalized Medicine
Assessing and implementing new diagnostics strategies for stratifying patients
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Soft condensed matter
What are the mysteries behind soft condensed matter?
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Rationally designed peptide based functional biomaterials
Promoter: J.G.E.M.Fraaije, Co-promotor: A. Kros
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Disentangling a complex genus: systematics, biogeography and bioactivity of the genus Phyllanthus L. and related genera of tribe Phyllantheae
The largest genus within the Phyllanthaceae family is a group called Phyllanthus L. Recent studies have shown, that Phyllanthus is paraphyletic with the genera Glochidion, Breynia and Synostemon nested within it.
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Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.