410 search results for “dna” in the Public website
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Host-Microbe Interactions in Plant Sciences
Plant Sciences' contribution to the Host-Microbe Interactions research theme is to dissect how microorganisms and microbiomes interact with the plant host and the insects on those plants, and how these insights may be harnessed to improve plant growth and health, by steering microbiome composition and…
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Leiden in the Caribbean
The research involves the application and combination of archaeological and archaeometrical methodologies. Petrographic analysis and isotopic provenance studies of raw materials and exotics, and the study of the distribution patterns of these materials are used to gain insight into the exchange of goods…
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Leiden Institute of Physics
Research at the Leiden Institute of Physics (LION) is foundational and curiosity driven. All our scientists share a desire to increase the knowledge of the world around us, in an open atmosphere of inquiry from which innovative ideas emerge that provide applications and value for society.
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Alternatives to animal experiments: Replacement, Reduction and Refinement
We aim to conduct as few animal experiments as possible. We are continually exploring methods to Replace, Reduce, and Refine animal experiments, commonly referred to as the three Rs. Additionally, we assess each study to ensure the implementation of the 3Rs has been maximised. The Animal Welfare Body…
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Water
We investigate water quality and want to understand the effects of human interference on aquatic biodiversity.
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Topology of polymer chains under nanoscale confinement: insights into genome folding
This month, a paper was published in Nanoscale by scientists from Dr. Alireza Mashaghi group at the Systems Biomedicine and Pharmacology Division in collaboration with the group of Dr. Sander Tans from TU Delft/AMOLF. In this paper, the authors studied how nanoscale spatial confinement affects the fold…
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Light-activatable metallodrugs and metal-functionalized liposomes
Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…
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Classes on offer
Below you will find an overview of all PRE-Classes provided by the various programmes of Leiden University. For each section, you can find a description of the content and more specific information about the requirements for participation in the Class.
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Movements of steroid receptors inside the cell nucleus unraveled
Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.
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Smart chemistry rids anti-cancer drugs of serious side effects
Researchers of the Leiden University Medical Centre (LUMC) and the Leiden Institute of Chemistry have made an important discovery about the commonly used anti-cancer drug doxorubicin. They have found a way to reduce its side effects without sacrificing the effectiveness of the medication. This is encouraging…
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The chemistry behind cancer drugs: searching for fewer side effects
PhD candidate Dennis Wander searches for the best of both worlds. That is to say: a cancer drug that is effective and also has minimal side effects. To this end, he makes new molecules inspired by two existing medicines. And not without result: ‘We have created a new variant that is very promising.’…
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alpine newts did not travel to the Netherlands themselves
Leiden biology students have determined the origin of exotic alpine newts in the Netherlands using a special DNA technique.
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Leiden experiments in DWDD University
Prof. Robbert Dijkgraaf used experiments and models from Leiden University for his tv lecture on symmetry. The lecture was broadcast live on channel 1. He showed that our DNA only twists in one direction using a plastic DNA model and he used a Chladni plate to show the symmetry of sound.
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Ahmed Mahfouz: 'The mystery of brain diseases, unravelled cell by cell'
Which brain cell does what, when Parkinson's disease arises? It won't be long before this jigsaw is solved piece by piece. Ahmed Mahfouz, computational biologist, combines bio-knowledge from Leiden with algorithms from Delft and is getting closer to finding the key.
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Development of Quantitative Nanostructure Activity Relationship (QNAR) Models Predicting the Toxicity of Metal-based Nanoparticles to Aquatic
Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…
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Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling
The close interaction between organic chemi stry and biology goes back to the late 18th century, when the modern natural sciences began to take shape. After synthetic organic chemistry arose as a discipline, organic chemists almost immediately began to pursue the synthesis of naturally occurring compounds,…
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Innate immune defence against intracellular pathogens
What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?
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Research
Physicists at the Leiden Institute of Physics (LION) conduct fundamental research into physical phenomena. They are inspired by curiosity and the desire to know more about the world in which we live. This research has always paved the way for new practical applications. These are something that the…
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Participating teams
Wondering who appeared at the start in 2019?
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Leiden Institute of Physics
Physicists at the Leiden Institute of Physics (LION) conduct fundamental research into physical phenomena. They are inspired by curiosity and the desire to know more about the world in which we live. This research has always paved the way for new practical applications. These are something that the…
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About Faculty of Science
The Faculty of Science is located at the Leiden Bio Science Park. It was founded more than two centuries ago and currently, more than 8000 people are working and studying at the eight institutes.
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Institute of Environmental Sciences
Natural resources are becoming increasingly scarce. If we want to maintain our current standard of living, we will need inventive solutions. The researchers at the Institute of Environmental Sciences (CML) share their thoughts on how to achieve a fully circular economy in which as little use as possible…
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16th International Metabolomics Workshop
The Basics and Applications to Plant Sciences will be held physical. See below for more information.
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Growth and development of actinomycetes
We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.
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Towards nano-MRI
By detecting the tiny forces between a micrometer sized magnet and the spins of hydrogen nuclei, we can do MRI with a volume resolution that is approximately 12 orders of magnitude better than a conventional MRI.
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Biophysical Organic Chemistry
The long term goal of the Biophysical Organic Chemistry/SSNMR group, headed by Prof. Huub de Groot, is to reach an understanding of structure, dynamics and functional mechanisms of membrane proteins and self-organized biological assemblies and to translate this knowledge into new concepts for nano-devices,…
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Institute of Biology
Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’
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Archaeological Sciences
With the emergence of new methods and technologies such as improved DNA analysis and big data, archaeological research has changed radically in recent decades. The researchers from the Department of Archaeological Sciences at the Faculty of Archaeology use new scientific knowledge to answer fundamental…
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Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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Crime and Criminal Justice (MSc)
Detecting and combatting crime is becoming increasingly complex. Security is high on the national and international agenda. The master’s programme Crime and Criminal Justice in Leiden provides the skills to face these challenges.
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Biology (MSc)
The master’s programme Biology at Leiden University offers seven specialisations ranging from Cell Biology to Molecular Genetics. The programme prepares you for a career in research within or outside academia.
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Why Leiden University?
The Physics and Education master specialisation gives you the opportunity to combine physics research with an excellent education in becoming a physics teacher.
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Research in Physics, Classical/Quantum Information (MSc)
This master’s programme combines Physics with Data Science. You will learn how physics has its own tricks to deal with big data and how techniques from machine learning and deep learning can be applied to classical and quantum data. The first focus of attention is on classical data, including data mining,…
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Why Leiden University?
The Physics and SCS master specialisation gives you the opportunity to combine Physics research with different aspects of science communication.
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Why Leiden University?
World-class research is integral part of the master’s education. You obtain a Physics degree from an institute with an international reputation. Research in this programme is fundamental and curiosity-driven.
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Neandertal Legacy
The genetic material of currently living Europeans is partly of Neandertal origin. Were our ancestors successful because they were hybridising and interacting with the local populations they encountered when migrating into new places? Reconstructing our evolutionary trajectory is key for rethinking…
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About the programme
Explore the contemporary dilemmas of archaeological heritage management, or focus on museum practices from an archaeological perspective.
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Reedijk Symposium 2024: Exploring the Nanomachinery and Substrate Functions of Mycobacterial Type VII Secretion Systems
Lecture
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450 years of Leiden University
Ahead of the times? We’ve been that for 450 years. As the oldest university in the Netherlands, we’ve sailed through the centuries with our sights fixed firmly on the society of the future. Our anniversary in 2025 is a chance to look back too. A chance to celebrate the impact of our research and teaching.…
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Genome size of wild tulips determined
Leiden researcher Dr Ben Zonneveld has determined the size of the genome - the amount of DNA per nucleus - of wild tulips. His conclusion is that there are more than 87 wild species. Various possibly new species have been discovered.
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The journey of our language in prehistoric times
For decades, scholars have wondered about the development and dissemination of languages around the world. What are the odds that peoples living thousands of miles apart speak varieties of Indo-European languages that are closely related? This riddle has now partly been solved thanks to an international…
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Next444: challenges for the future
On a wintry Wednesday evening, big issues were the topic of conversation at Grand Café de Burcht. Young Academy Leiden (YAL) was holding a round table: Next444. Now the 444th anniversary of Leiden University is over, it’s time to look once again to the future. What issues will we be facing over the…
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Pascal Professor 2015
In 2015 the Pascalchair of the Faculty of Science, Universiteit Leiden and in particular of Leiden Institute of Advanced Computer Science, is held by Prof. Dr. Natasa Jonoska, University of South Florida, Tampa, USA.
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Seven Leiden researchers win €1.5m Vici grant
Seven Leiden researchers have each been awarded a Vici grant by the Netherlands Organisation for Scientific Research (NWO). This will enable them to form a research group and develop their own innovative line of research.
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How did Proto-Indo-European reach Asia?
Five thousand years before the common era (BCE), Proto-Indo-European, the mother of many languages that are spoken today in Europe, Central Asia and South Asia, originated in eastern Europe. PhD candidate Axel Palmér has combined a 175-year-old hypothesis with new techniques to demonstrate how descendants…
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Mapping of bacterial genomes to combat infectious diseases
Mapping of bacterial genomes to combat infectious diseases
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Soil bacteria can produce a wealth of new antibiotics
Soil bacteria can produce a wealth of antibiotics that are new to us, claims Gilles van Wezel, Professor of Molecular Biotechnology at the Institute of Biology Leiden. His research group has developed a method that can rapidly identify and produce these unknown compounds.
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Collaborating bacteria sacrifice themselves for the greater good
Like ants, termites and bees, some bacteria work together as a multicellular group. There is a strict division of labour in such colonies, to make the group more resilient to the outside world. Now researchers have found that some parts of the bacterial colony can take ‘for the greater good’ to a whole…
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The African lion consists of two subspecies
Biologist Laura Bertola argues that the traditional separation of lions into African and Asian subspecies is incorrect. She has discovered that Africa is actually home to two subspecies. Her PhD defense was on 18 March 2015.