2,531 search results for “equal treatment discriminatie” in the Public website
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Tailored treatment for colon and rectal cancer
PhD defence
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Harnessing neoantigens for targeted cancer treatment
PhD defence
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Topic: Persistent physical symptoms
Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…
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Education
The Clinical Psychology Educational Programme aims to provide specialized knowledge of psychopathology, diagnostic and treatment skills and related scientific research.
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Redemption in the Old Babylonian period: texts, archives, practice
Stephen Moore defended his thesis on 26 May 2020.
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Topic: Work and health
The research connected to this topic is related to Work and health.
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Veni grant for Nadine Raaphorst: 'I kept checking whether it was really true'
Nadine Raaphorst, university lecturer at the Institute of Public Administration, has been awarded a Veni-subisidy from science financier NWO. This grant of up to 250,000 euros will enable her to set up her own research in the coming years. Raaphorst's research is about consistent decision-making by…
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Evaluation of synergistic effects of Chinese herbal medicine and natural compounds on cancers
What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?
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Severe behavioral and emotional problems, special education and youth care
Which educational and child welfare interventions offer optimal opportunities for positive development to children with severe behavioral and emotional disorders.
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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Clinical Psychology
Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.
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Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Translational Immuno-Pharmacology
The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…
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The Legal Revolution Against the Accommodation of Religion: The Secular Age v. The Sexular Age
On 27 June 2019, Barry Bussey defended his thesis 'The Legal Revolution Against the Accommodation of Religion: The Secular Age v. The Sexular Age'. The doctoral research was supervised by Prof. dr. P.B. Cliteur.
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Brave Steps
A step-by-step approach to building confidence in anxiety-prone young children.
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Resetting the immune system to cure diabetes and rheumatism
In autoimmune diseases such as rheumatism and diabetes the immune system attacks autologous proteins. Leiden researchers are trying to discover how this comes about.
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Quantitative Pharmacology Approaches to Inform Treatment Strategies Against Tuberculosis
PhD defence
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Influencing your health with your behaviour and thoughts
Psychological processes have a major effect on the course of a disease and the effects of medical treatment. Researchers in the field of Psychoneurobiology examine the interactions between body and mind. They investigate the effects of stress as well as the effect of placebos and nocebos, which can…
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Epilepsy and anxiety: targeting a vicious cycle
How effective is eye movement desensitization and reprocessing therapy in targeting epilepsy-related anxiety?
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Australia
This is an Erasmus+ International Credit Mobility project of the Faculty of Social and Behavoriural Sciences with Macquarie University in Australia.
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PROPER: ‘Near-patient’ prostate cancer models for the assessment of disease prognosis and therapy
How to identify patients at risk of developing devastating, metastatic disease and facilitate the development of personalised treatment for prostate cancer patients?
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Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
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LED3 Drug Discovery Case Studies
To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.
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Stromal cells suppress immune response symptoms
A new therapy for the serious Graft-versus-Host disease
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Metabolomics and Analytics Centre
The ambition of the Metabolomics and Analytics Centre led by Thomas Hankemeier is to develop innovative analytical strategies for metabolomics-driven health monitoring and systems biology studies. Understanding the intricate balance between health, disease and adaptation to challenges relies on the…
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The Hittite Inherited Lexicon
This dissertation attempts to describe the linguistic history of Hittite on the basis of a systematic etymological treatment of its entire inherited lexicon, precisely analyzing the phonological and morphological developments.
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Facing your fears together
Peer-mentored cognitive behavioral therapy for adolescents with mild intellectual disability and anxiety disorder
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Programme structure
The master's specialisation Clinical Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.
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Effects of noninvasive vagus nerve stimulation on perseverative cognition
Can excessive worrying be reduced via stimulation of the vagus nerve?
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Sophia Women's Network
Sophia aims to create equal opportunities and promote a better working climate for female academic staff at Leiden University.
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Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
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Special education and autism
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Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Chemical biology of antigen presentation by MHC molecules
MHC class I and MHC class II molecules present peptides to the immune system to drive proper T cell responses. Pharmacological modulation of T-cell responses can offer treatment options for a range of immune-related diseases.
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Are we there yet? Advances in anytime-valid methods for hypothesis testing and prediction
Statistical considerations guide the design and implementation of the experiments that scientists perform. For instance, in a clinical trial about a the efficacy of a treatment, its effect in a certain minimum amount of patients has to be observed in order to make confident assertions about the efficacy…
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Immunity in atherosclerosis: novel assays, biomarkers and therapeutic approaches
Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.
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Data science for tax administration
In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.
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Chronobiology of depression
What are the circadian disturbances underlying depression vulnerability? How are they related to mood, cognition and sleep ?
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Voila/Neuromet
To be able to identify, slow down and reverse functional deterioration in the elderly to give them more years of good health.
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Topic: E-health
The research connected to this topic is related to E-health.
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Systems Pharmacology
The aim of the research programme Systems Pharmacology lies in the development of personalised medicine strategies, and development of new systems-based approaches in translational and clinical pharmacology.
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ACTION
Aggression inflicts a huge personal, psychological and financial burden on affected individuals, their relatives, and society at large. Despite large scientific, preventive, and treatment investments, no decrease in aggressive behaviour is seen. By combining interdisciplinary expertise the ACTION consortium…
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Disrupting the transcriptional machinery to combat triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.
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Group representations in Banach spaces and Banach lattices
Promotor: S.M. Verduyn Lunel, Co-promotores: M.F.E. de Jeu, B. de Pagter
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Self-Adjusting Surrogate-Assisted Optimization Techniques for Expensive Constrained Black Box ProblemsBagheri, S.
Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.
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Arakelov inequalities and semistable families of curves uniformized by the unit ball
The main object of study in this thesis is an Arakelov inequalitywhich bounds the degree of an invertible subsheaf of the direct image ofthe pluricanonical relative sheaf of a semistable family of curves.
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The Egalitarian Constitution
On 18 september 2018, Jonathan Price defended his doctoral thesis 'The Egalitarian Constitution'. The doctoral research was supervised by Prof. dr. A.A.M. Kinneging.
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Islam: Religion and Society
Islam is a religion as well as a cultural practice that takes on a diversity of forms, some of them contradictory. This has always been the case, and it is becoming increasingly apparant in the modern world through migration, globalisation and the digitial media. The minor Islam: Religion and Society,…
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Firearm Homicides in Europe: A comparison with non-firearm homicides in five European countries
This paper presents the prevalence and characteristics of firearm homicides in Denmark, Finland, the Netherlands, Sweden and Switzerland