321 search results for “cancer drug resistance” in the Staff website
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How a pathogenic bacterium searches for food
Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.
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Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.
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Royal honour for emeritus professor Ad IJzerman
Ad IJzerman, Emeritus Professor of Pharmacochemistry, was made a Knight of the Order of the Lion of the Netherlands on 26 April. He was presented with the royal honour by Mayor Elbert Roest in the town hall in Bloemendaal.
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Looking at toxicodynamic variation in the human population to address chemical safety
The European Food Safety Authority (EFSA) has awarded a €1.6M contract to an LACDR-led consortium to assess how sensitivity to toxicity caused by chemicals varies among individual people. Currently these toxicodynamic differences are an unknown source of uncertainty when carrying out risk assessment…
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These eleven Leiden Science researchers are among the most highly cited
Eleven researchers of the Faculty of Science are on the 2021 Highly Cited Researchers list of Clarivate Analytics. Only 0.1 per cent of researchers are included in this list, literally making them one in a thousand.
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Natalia Ortiz – Winner of the 2019 - 2020 KNCV Medicinal Chemistry & Chemical Biology thesis prize
Natalia Ortiz (Division of Drug Discovery and Safety) has been awarded the 2019-2020 PhD-thesis prize by the Division of Medicinal Chemistry & Chemical Biology, from the Royal Netherlands Chemical Society (KNCV-MCCB). The KNCV-MCCB thesis prize is a biannual award which is granted to the best PhD thesis…
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Maaike van der Lee wins the national PhD competition 2021 at the FIGON Dutch Medicine Days
We are congratulating Maaike van der Lee, PhD candidate at LUMC-KFT, for winning the national PhD competition 2021 at the FIGON Dutch Medicine Days. During this national competition, 8 researchers from the major university cities in the Netherlands present their work in the field of innovative medicine…
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CSC-Leiden University Scholarship
PhD
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Cleveringa Professor: Holocaust remembrance has led to very different political lessons
From memorials to the armed forces to memory stones for individual victims. It was only later that the Holocaust took a central role in Western remembrance culture, Cleveringa Professor Frank van Vree notes. ‘Nationalists and human rights activists both invoke the experience of the Holocaust.’
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Leiden Classic: 4 Questions on the origins of the university and the Dies Natalis
Every year around 8 February, Leiden University, the oldest university in the Netherlands, is celebrating its birthday. Why does the King still receive a telegram on the day of the Dies Natalis? 4 questions on the origins of Leiden University and its traditions for celebrating its foundation day.
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Farewell to Diversity Officer Aya Ezawa: Tireless advocate for D&I
Aya Ezawa bade farewell as Diversity Officer of Leiden University at a celebration in the Academy Building on 11 June. Since her appointment in 2019, she has been a tireless advocate for culture change and a champion for diversity, inclusion and equal opportunities for all.
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Templeton Grant Drukker News
In a project funded by the John Templeton Foundation to the group of Micha Drukker, scientists will produce stem cells from short and long living understudied species to model cellular and organismal lifespan.
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Miranda van Eck new Scientific Director of the LACDR institute
As of 1 September Miranda van Eck will be the new Scientific Director of the Leiden Academic Centre for Drug Research. She succeeds Hubertus Irth, who led the institute since 2016. Van Eck has been appointed for a period of four years.
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LACDR-Bruker Bio-AFM workshop: connecting disciplines through force spectroscopy
On the 6th and 7th of September 2023, the Leiden Academic Centre for Drug Research (LACDR) organized the Leiden Bio-AFM workshop in cooperation with Bruker Nano GmbH (Germany) and Bruker Nederland BV. The organization of this event was led by the Medical Systems Biophysics and Bioengineering group (Alireza…
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Rawi Ramautar new Programme Director of Bio-Pharmaceutical Sciences bachelor’s program
Rawi Ramautar will be the new Programme Director of the bachelor of Bio-Pharmaceutical Sciences starting September 1. The appointment is for four years. Ramautar succeeds Erik Danen, who has held the position since 2019.
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Suzanne van der Pluijm to be Science Faculty’s new Executive Director
Suzanne van der Pluijm will be appointed Executive Director and Member of the Board of the Faculty of Science with effect from 1 June 2022. She succeeds Ed van den Berg, who has held this position on an interim basis since 1 September 2021 .
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New research into hidden nature in our cities
What hidden nature is there in our cities and how can we use such organisms? This is what the HiddenBiodiversity project will be exploring over the next four years. The project’s kick-off meeting was held at the Hortus botanicus on Monday 26 September.
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New insights into mycobacterial infections with NWO grant
Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…
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Making the invisible visible with ‘click chemistry’
Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.
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Leiden research project on circular electronics receives 3.8 million euros from NWO
Fewer CO2 emissions, less airborne viral transmission, and a more sustainable form of food production: seven consortia of researchers and societal partners will put a budget of 32 million euros towards developing technological innovations. Important Leiden research on circular electronics by Prof. Dr.…
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‘We couldn't really celebrate our vaccine being approved, but we were over the moon’
On 11 March, pharmaceutical company Janssen received approval to launch its corona vaccine on the European market. This made Janssen the fourth company to be given the green light by the European Medicines Agency. As Lead of the Janssen Campus in the Netherlands, Biology alumnus Bart van Zijll Langhout…
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Nobel Prize winner visited Leiden: 'We have hosted a scientific rockstar'
On 28 September the famous chemists Carolyn Bertozzi visited Leiden University to speak at the LED3 seminar. Just one week later, she was announced winner the 2022 Nobel Prize in Chemistry. Leiden chemists Sebastian Pomplun and Hermen Overkleeft are fan: ‘We are extremely honoured to have hosted this…
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Lowlands as lab: virtual trips in the name of science
While tens of thousands of visitors dance to deafening music, a team of Leiden psychologists are trying to collect data for their research at Lowlands. How do festivalgoers experience a virtual trip? And what role do factors such as too little sleep and whether they have experience with psychedelics…
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Atherosclerosis resembles an autoimmune disease. Marie Depuydt graduated on this topic, with honours
In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…
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Scouring the brain for causes of psychiatric illnesses
What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’
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Gilles van Wezel steps down as SD of the IBL: Hubertus Irth appointed as temporary replacement
Gilles van Wezel will step down as Scientific Director (SD) of the Institute of Biology Leiden (IBL) as of June 17th. He has held this position since September 2018. Van Wezel will be temporarily succeeded by Hubertus Irth, the current SD of the Leiden Academic Centre for Drug Research (LACDR). Irth…
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Rubicon grant for four Leiden researchers
Four promising young researchers from Leiden University have received a Rubicon grant from the Dutch Research Council (NWO). This grant will enable them to gain valuable research experience at top universities abroad.
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A plan of the faculty: 'In France, it would have been a plan of the boss'
The moment has finally arrived: after months of hard work, the strategic plan is finished. It was an interesting period, thinks core group member Sylvestre Bonnet. 'How we finally arrived at this strategic plan was very different from what I had thought beforehand.'
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The hunt for nanoplastics is on
How do you count the nanoplastics in your body? Leiden researchers published a method in Nature Protocols today that should make this easier. Important for both environmental and medicine research.
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Exhibition shows the ‘beauty and power’ of mathematics
In the ‘Imaginary’ exhibition, its curators show how society is made up of mathematics. From algorithms that save lives to ones that generate art. The exhibition is from 2 June to 25 July at Oude UB in Leiden.
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Why arteriosclerosis looks like an autoimmune disease
Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the renowned scientific journal Nature Cardiovascular Research. 'This discovery suggests that treatment methods for autoimmune diseases might also be effective…
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Be amazed and inspired during the Leiden Science Family Day!
On Sunday 8 October 2023, during the Weekend van de Wetenschap, the Faculty of Science of Leiden University will open its doors to anyone curious about science from 11.00 to 16.00 hrs! Explore a world of wonder and discovery; where science is transformed into an unforgettable adventure. Intriguing…
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Master's student Nicole ter Laak wins KNMP Studentenprijs 2023
Biopharmaceutical sciences master's student Nicole ter Laak has won the KNMP Studentenprijs 2023. She wins the prize for her research project on dosing guidelines of antibiotics in newborn babies with a very low birth weight for gestational age.
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Heineken Young Scientists Award for three Leiden researchers
Three of the four Heineken Young Scientists Awards for 2022 have gone to researchers from Leiden: chronobiologist Laura Kervezee, physicist Jordi Tura i Brugués and health psychologist Liesbeth van Vliet.
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Understanding superconductivity comes closer with major ERC grant for Milan Allan
Physicist Milan Allan will build an instrument that will bring superconductivity research further. He has been awarded an ERC Consolidator Grant of 2 million euros over the next five years. With his PairNoise programme he aims to detect paired electrons as they occur just above the temperature at which…
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Research project into environmental tipping points receives €10 million
Arjen Doelman (Leiden University), Max Rietkerk (Utrecht University), Ehud Meron (Ben-Gurion University of the Negev) and Isla Myers-Smith (University of Edinburgh) received an ERC Synergy grant of 10 million euros with their RESILIENCE project. The researchers will investigate whether and how tipping…
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Improving the treatment of pathogenic fungi. ‘The process is working, but not that well…’
Fungi germinating in the lungs of patients. Doesn’t sound too nice, does it? Luckily, humans can deal with this normally, and we are able to clear the infection before anything comes to harm. However, in people with health issues, Aspergillosis can cause a lot of damage, especially if the fungus becomes…
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Woman, man or somewhere in between? You decide (and not just your body)
A female body equals a woman. Nonsense, says Professor by Special Appointment to the Socrates Chair Annemie Halsema. She argues that our sense of identity and social environment also determine our identity. ‘We should stop assigning people’s sex at birth.’
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Communication about quantum technology offers many opportunities (but there are risks too)
Watching and analysing hundreds of TEDx talks, that too can be research. That becomes clear from the work of PhD student Aletta Meinsma, who is studying potential problems in popular communication about quantum technologies. She explains how she approaches this and why it is so important.
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A quick call with Pancras Hogendoorn about the LUMC art auction
Always wanted to go to a real art auction? Now’s your chance! On 15 February over a hundred works from the LUMC’s art collection will go under the hammer. ‘It’s great fun just to be there, regardless of whether you buy anything,’ says dean and auctioneer Pancras Hogendoorn.
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Artificial intelligence project to accelerate MRI scans receives 2 million euros
Leiden University Medical Center (LUMC), Leiden University and Philips are jointly receiving over 2 million euros from NWO to set up an artificial intelligence (AI) lab. The aim of this lab is to accelerate and improve MRI scans with AI. This is great for patients, and it helps make MRI more accessi…
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Four Leiden consortia awarded large NWO grants
No less than four Leiden research teams have been awarded a grant by NWO. On 27 July NWO honoured 21 applications in the Open Competition ENW-XL. NWO awards the grants to consortia in the exact and natural sciences who are doing unconnected fundamental research that is 'driven by curiosity'.
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Jasper's Day
Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.
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Visit by Members of Parliament highlights interdisciplinary research and collaboration
High-quality education, research involving multiple faculties, collaboration between universities and central government funding to make all this possible: these were the topics covered in a working visit of the Standing Committee for Education, Culture and Science (OCW) to the Association of Universities…
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The LeiCNS-PK3.0 model development and applications: Healthy-to- diseased CNS pharmacokinetic translation
PhD defence
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‘Sleep should play a greater role in lifestyle research’
Sleep disorders have a significant influence on our physical and emotional health. Sleep should therefore receive more attention within lifestyle medicine, says Professor Gert Jan Lammers. He will give his inaugural lecture on Friday 20 May entitled: ‘Getting to sleep’.
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Ecologist Michiel Veldhuis is the Discoverer of the Year 2020
Michiel Veldhuis received the most public votes for the C.J. Kok Public Award and may therefore call himself Discoverer of the Year. Veldhuis researches how climate change affects savannah ecosystems in Africa and how we can protect them.
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Executive Board column: Annetje Ottow on the importance of student associations
Now the introduction weeks can go ahead as usual, the new students’ enthusiasm is overwhelming. It’s back to normal for the student associations too, having had a hard time of it during the pandemic.
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De dag van Jasper
Jasper Knoester is de decaan van de Faculteit Wiskunde & Natuurwetenschappen. Hoe gaat het met hem, wat doet hij precies en hoe ziet zijn dag eruit? In elke nieuwsbrief geeft Jasper een inkijkje in zijn leven.
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Lindsey Burggraaff wins Krijn Rietveld Memorial Innovation Award
Data scientist Lindsey Burggraaff has won the second edition of the Krijn Rietveld Memorial Innovation Award. She receives the prize for her research into bioactive substances in food. ‘Burggraaff's work is situated at a unique intersection of data science, biochemistry and the fields of food and nutrition,’…