760 search results for “antibiotic resistance” in the Public website
-
Microbial Induction of Plant Resilience to Drought Stress (MicroRes)
What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?
-
(Un)timely Crises Chronotopes and Critique
This book explores how ‘crisis’ - as a narrative, concept, grammar, and experience - structures time and space.
-
Crisis and Critique Network
This network brings together scholars whose work explores how contemporary frameworks of crisis produce experiences of the present, rehash or disrupt established narratives of the past, and broker specific outlooks on the future. We collaborate in studying these crisis-scapes and exploring how they…
-
Unravelling the genes responsible for life history traits in the giant woody cabbage (Brassica oleracea)
Which genes are involved in woodiness and associated traits such as drought tolerance, flowering time, stem elongation, life span, and plant herbivory, and how do these gene regulatory pathways overlap?
-
Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
-
Towards a feminist playology: social sport studies and the limits of critique
The making of sacrifices seems part and parcel of any elite sportsperson’s life. Remarkably, the insights that we find in the current literature in social sport studies are not able to make sense of the references to sacrifice in the data that emerged in the context of this study on the social significance…
-
Evolution & Biodiversity in Plant Sciences
Plant Sciences' contribution to the Evolution & Biodiversity research theme is to understand what are the key drivers of plant biodiversity during evolution with a focus on plant life history and resilience traits and develop tools to restore and maintain plant biodiversity.
-
Paths through slavery: urban slave agency and empowerment in Suriname, 1700-1863
How did slaves in the eighteenth century manage to empower themselves and their kin, and why did this become all the more difficult in the nineteenth century?
-
Nitric oxide in defence against mycobacterial infection
Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?
-
Research
Research at the Macromolecular Biochemistry group is comprised of the following research themes:
-
Growing up to be fearful?
Social evaluative fears during adolescence
-
Post-Soviet Nostalgia. Confronting the Empire's Legacies
Bringing together scholars from Russia, the United States and Europe, this collection of essays is the first to explore the slippery phenomenon of post-Soviet nostalgia by studying it as a discursive practice serving a wide variety of ideological agendas.
-
The added risk of size
What are the risks of nanoparticles?
-
Dynamics of a β-lactamase
BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.
-
Politics and Aesthetics
Politics and Aesthetics is one of the six research themes of the LUCAS Modern and Contemporary cluster.
- Prof Dr Matthias Erb
-
Core cross-linked polymeric micelles based on polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
-
Dividing Worlds
Dividing Worlds: Tsunamis, Seawalls, and Ontological Politics in Northeast Japan
-
Computational aspects of class group actions and applications to post-quantum cryptography
Most of current public-key cryptography is considered insecure against attacks from sufficiently powerful quantum computers. Post-quantum cryptography studies methods to secure information resistant against such attacks. One proposal is isogeny-based cryptography, which bases its security on computational…
-
El presente incómodo: subjetividad en crisis y novelas cubanas después del muro
This book aims to understand cultural transitions and negotiations between art and politics from 1989 to 2020 through analysis of a series of Cuban novels.
-
Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
-
Unraveling the role of signaling networks controlled by Grainyhead like transcription factor in breast cancer subtypes
This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…
-
Hye Kyong Kim
PhD at the Natural Product Laboratory, Institute of Biology, Leiden University - the Netherlands
-
About the programme
In the Master's programme Crisis and Security Management, specialisation Governance of radicalism, extremism and terrorism we focus on the academic body of knowledge on different form of protests, contention, resistance and violence. We explore and explain the emergence of radical and extremist move…
-
Experiment Square
Are you the scientist of the future? Come experiment with science at the Experiments Square! Make your own slime, discover how rubber can count, play along with the antibiotics game, discover the power of light and much more!
-
Caribbean Connections: Cultural Encounters in a New World Setting (CARIB)
What socio-cultural transformations did indigenous communities in the Lesser Antilles undergo from the late precolonial to the early colonial period in response to Amerindian European-African cultural encounters? How did Amerindian populations realign themselves in response to the colonisation…
-
Alexander van Oudenhoven Discoverer of the year 2016
Environmental scientist Alexander van Oudenhoven has been chosen as Discoverer of the year of the Faculty of Science. Vice Rector Magnificus Hester Bijl announced this during the faculty’s New Year’s Reception on 10 January. Biologist Changsheng Wu won the prize for best dissertation of 2016. Computer…
-
Professor Lars Jeuken wants to use bacteria for sustainable fuel
On 1 August, Lars Jeuken started work as Professor of Biophysical Chemistry at the Leiden Institute of Chemistry (LIC). His research is at the intersection of biology and chemistry, but also involves physics and nanotechnology. Jeuken: ‘By linking nanoparticles to proteins and bacteria, we want to convert…
-
Public perception of energy projects
The transition from fossil fuels and the practical changes that this entails make many demands on citizens. Emma ter Mors, a psychologist and lecturer at Leiden University, is researching the factors that contribute to public perception and acceptance of new energy technologies.
- Rightless Resistance: Palm Oil and the Struggle for Land and Citizenship in Indonesia
-
Altruism in bacteria: colonies divide the work
Bacteria found in soil specialise in the colony by division of labour. Some of the bacteria produce antibiotics, even when it comes at the expense of their individual reproduction success, to defend their colony against competitors. Publication in Science Advances.
-
Hypoxic Signalling and Tuberculosis
IBL-researcher Phil Elks in the group of Annemarie Meijer won the Cell Observatory Publication of the Year 2013. He received the award for his paper in PLoS Pathogens, showing that activation of hypoxia signaling protects against mycobacterial infection.
-
functional genetic screens to understand and overcome PARP inhibitor resistance
PhD defence
- Cold War
-
Glucocorticoid modulation of the immune response
Unraveling the immune-suppressive actions of drugs like prednisone.
- Book Chapters
-
Development & Disease in Plant Sciences
Plant Sciences' contribution to the Development & Disease research theme is to unravel the processes that allow plants to adapt to changing abiotic and biotic environmental conditions or stresses, with the aim to contribute to the sustainable production of food, flowers and bio-based products using…
-
About the programme
The one-year master in South Asian Studies, a specialisation of Leiden University’s master in Asian Studies, offers a large and varied selection of subjects and the freedom to choose the areas on which you will focus.
-
About the programme
The one-year master in Southeast Asian Studies, a specialisation of Leiden University’s master in Asian Studies, offers a large and varied selection of subjects and the freedom to choose the areas on which you will focus.
-
Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
- Brought under the law of the land
-
Flow: A study of electron transport through networks of interconnected nanoparticles
This thesis describes a study from both a theoreticaL and an experimental point of view.
-
Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
-
Breaking the witches' spell: towards steering the soil microbiome for volatile-mediated control of the root parasitic weed Striga
Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.
-
Rudolph Cleveringa
On 26 November 1940 Rudolph Pabus Cleveringa (1894-1980) gave his now famous protest speech.
-
From respected hermits to ordinary citizens: The conversion of the Baduy, ethnicity, and politics of religion in Indonesia (1977 - 2019)
Mr. Ade Jaya Suryani defended his thesis on 28 January 2021
-
Soft condensed matter
What are the mysteries behind soft condensed matter?
-
Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
-
State, Society and Labour: A Social History of Iranian Textile workers, 1906-1941
This research investigates everyday lives and workplace experiences of Iranian workers employed at textile industry, which was the second biggest industry after oil following the latter’s discovery in 1908.
-
Thiosugars: reactivity, methodology and applications
Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…