319 search results for “drug” in the Staff website
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Podcast: A changing view on psychedelics
We talk with Michiel van Elk, about his research into mapping what effects psychedelics have on the human brain and what this means for the possible clinical application of these drugs. The cognitive psychologist shares his findings with a sober view, bringing critics and fanatics closer together for…
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How to make an old antibiotic a hundred times more potent
Nathaniel Martin, Professor of Biological chemistry, wondered what would happen if you take an antibiotic that has been known for 70 years and try to improve it with the latest tools of modern chemistry. Turns out it can become up to a hundred times more potent and prevent the growth of some drug-resistant…
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Dies Natalis all about innovating and connecting
‘We could share our knowledge more with others and apply it more widely,’ said Annetje Ottow, President of the Executive Board, while presenting the new Strategic Plan on the University’s 447th Dies Natalis. The new Strategic Plan therefore focuses on innovating and connecting, among disciplines and…
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ULLA workshop – summer school - courses
We are proud partner of the ULLA. It is the European University Consortium for Pharmaceutical Sciences in which LACDR participates for already 30 years. We have the honor to host the ULLA workshop in 2023 and the ULLA summer school in 2024.
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Prof Dr Joke Bouwstra receives the “ Dr Saal van Zwanenberg Ereprijs”
Prof Dr Joke Bouwstra will receive the “ Dr Saal van Zwanenberg Ereprijs” from the “Koninklijke Hollandse Maatschappij der Wetenschappen” on November 14 in Haarlem. Joke is awarded for her innovative contributions to the field of skin delivery science and technology. She shares the price with prof…
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Tamara Danilyuk wins the EUROTOX 2023 Early Career Award
I am thrilled to share the exciting news of being honored with the 2023 Early Career Award at the EUROTOX conference held in Ljubljana, Slovenia. This recognition, presented by ECETOC (European Centre for Ecotoxicology and Toxicology of Chemicals) and dedicated to the memory of Dr. Christa Hennes, holds…
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Interview Micha Drukker
Micha Drukker
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Nature Communications paper on therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.
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Interview
Sabine de Winter
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Erasmus+ grant for 13 exchange projects
Thirteen Leiden University exchange projects have been awarded an Erasmus+ International Credit Mobility grant. The total award of around 450,000 euros will enable 103 students and staff to go on an exchange.
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Psychologists participate in high-tech biomarker research in health care
Next generation immunodermatology (NGID) is a nationwide, large-scale project, funded by a large grant of the Dutch NWO to unravel novel biomarkers for six different skin diseases. These biomarkers will drive a high-tech, patient-centric approach in clinical practice. Health psychologist Sylvia van…
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KiKa grant for mathematician: how statistics helps fight bone cancer
Using mathematics to help children with bone cancer. It sounds a little strange, but for statistician Marta Fiocco, it's just her job. She gets a substantial grant from KiKa for it. With that money, she is going to study the effect of chemotherapy adjustments.
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Proof of Concept grants for four Leiden researchers
Four Leiden researchers have been awarded Proof of Concept grants by the ERC. These grants, each worth 150,000 euros, help researchers translate the findings of previous ERC projects into innovative practical applications.
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This is the library you did not know you had been looking for
2,240 plant extracts from 1,299 different plant species of Dutch origin. That’s the collection of the Dutch Extract Library, which has recently been transferred to the Institute of Biology Leiden. To plant biologist and contact person for this library Pingtao Ding this is a true treasury. ‘To bring…
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Professor calls for more focus on brain impairment in offenders
Maaike Kempes believes more attention should be paid to non-congenital brain injuries in suspects. This may partly explain their criminal behaviour.
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700,000 euros for the fight against aggressive breast cancer
To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…
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EUFEPS congres
EUFEPS Women in Pharmaceutical Sciences Award for Jara Bouma
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Erik Danen new Dean of the Graduate School of Science
The Graduate School of Science starts 2024 with a new Dean. The Faculty Council appointed Erik Danen for the coming four years. He succeeds Eric Eliel, who has held the position since May 2020.
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Can Parkinson's be stopped by unravelling protein fibres? Anne Wentink finds out with a Vidi grant from NWO
In brain diseases such as Parkinson's and Alzheimer's, proteins clump together to form fibres. ‘Chaperone proteins’ unravel those fibres, but in the test tube biochemist Anne Wentink saw that this can also cause new problems. She is going to find out what happens inside cells to determine what a drug…
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Looking at the person beyond the blood clot
How can we improve the treatment of thrombosis, reduce the disease’s impact and spend less money while we’re at it? This is what Erik Klok, Professor of Internal Medicine and an internist, is researching. He will discuss it in depth in his inaugural lecture on 10 March.
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Improving nature’s antibiotic
'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…
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Study associations sign covenant: limit your alcohol consumption and look after each other
Opting more often for mocktails or soft drinks rather than beer or wine, talking to others about their drinking and pointing out the ban on drugs. Leiden University’s new covenant on alcohol and drugs for study associations encourages providing more alcohol-free alternatives.
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Superselective bonds light up
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…
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Seven Comenius grants for Leiden lecturers
Eleven lecturers from Leiden University have been awarded Comenius grants that will allow them to work with their teams on an innovation project within their own teaching. They have been awarded three grants of 100,000 euros within the Senior Fellows programme and four grants of 50,000 euros within…
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On this public day on psychedelics, researchers transcend the media hype
Never before has so much research been carried out on the therapeutic effect of psychedelic drugs. Researchers at the LIBC Public Day are happy about the effect the drugs can have on depression, anxiety and PTSS, but at the same time they have some doubts. ‘The hype is bound to crash before long.’
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Sibel Bahtiri is one of the new Faces of Science: ‘I want to show how we’re finding alternatives to animal testing’
PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.
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How Europe will be better prepared for the next pandemic
The European PANVIPREP research project started at the Leiden University Medical Center on 11 March. The participants are virologists, biochemists and pharmacists from 14 European countries. Their mission is to develop antiviral drugs to protect Europe during pandemics. At least two such antivirals…
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Carlijn Lems wins the Suzanne Hovinga Award 2020-2021
During the LACDR Fall Symposium the Suzanne Hovinga Award for ‘best master thesis’ was awarded to Carlijn Lems for her master thesis entitled ‘Elucidating the crosstalk between epithelial-to-mesenchymal transition and Programmed Death-Ligand 1: validation and extension of a computational model’. Carlijn…
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The future of artificial intelligence
From self-driving cars to innovative drug development, artificial intelligence (AI) is going to fundamentally change our lives in a variety of ways.
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Niek Kijk in de Vegte wins the Suzanne Hovinga Award 2023
During the LACDR Fall Symposium, Niek Kijk in de Vegte received the annual Suzanne Hovinga Award for the best master thesis. Niek performed his RP1 research under the supervision of Dr. Natalia Ortiz Zacarias and Prof.dr. Laura Heitman in the Molecular Pharmacology group at the Division of Drug Discovery…
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LACDR Fall Symposium 2021
On Thursday the 9th of December the LACDR Fall Symposium 2021 took place. Although the plan was to organize this symposium physically, unfortunately this was not possible due to the corona measures and it became an online event.
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Towards translation of CNS pharmacokinetics from mice to men
PhD candidates Mohammed Saleh and Berfin Gülave (Division of Systems Pharmacology and Pharmacy) published their research paper on “Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice”.
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Douwe D. Breimer Research fund
Prof. dr. Douwe Breimer, emeritus Professor of Pharmacology, former Rector Magnificus and founder of LACDR has established a foundation to stimulate, support, and promote scientific meetings in the field of Pharmacology. Particularly those concerned with fundamental research and mathematical modelling…
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Introduction to entrepreneurship
On the 8th of March the first "introduction to entrepreneurship" boot camp was held at PLNT specifically for PhD researchers at the LACDR. During the two hour block topics such as "the core of entrepreneurship", "spotting opportunities" and "what is your value proposition" were discussed.
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Willem van der Does sheds new light on the at times pitch-black history of psychiatry
Piercing through the skull with an ice pick, administering electric shocks without an anaesthetic, or applying leeches to the uterus: these may seem like medieval methods of torture, but they are in fact therapies used in medicine. Willem van der Does writes about all of them in his new book. ‘Physicians…
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Race against time: Helping the Netherlands secure almost 20 million Pfizer vaccines
The whole world is waiting anxiously for sufficient supplies of coronavirus vaccines. As Launch Navigator at Pfizer, alumnus Dennis de Mik must help ensure that the Netherlands receives 19.8 million doses of the Pfizer/BioNTech vaccine. How is he going about this and how has his Bio-Pharmaceutical Sciences…
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Psychologists at Lowlands Science: can virtual reality trigger a psychedelic experience?
Fantastic plants, dizzying patterns and pulsating sounds: researchers from Leiden are going to study the effects of a simulated psychedelic trip on the mind and body at Lowlands Festival. Why might this be interesting for therapies?
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The Erasmus+ grant opens doors
What is it like to participate in the Erasmus+ grant programme as a Master's student from Ukraine? Yevhenii Radchenko did an eight-month internship at Leiden University in 2018. Soon after, he returned as a PhD candidate. 'You have little to lose, but a lot to gain.'
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A lifeline for Leiden research – TB solution a step closer thanks to this Indonesian university
Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…
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On barriers and bridges: autoimmune rheumatic diseases and the road to a cure
Hans Ulrich Scherer is Professor of Rheumatology, in particular Translational Rheumatology. He wants to build bridges between research and clinical practice and between departments and organisations at home and abroad. Scherer will give his inaugural lecture next Friday. ‘To make progress, we have to…
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NWO-XS grants for two innovative research projects
Two Leiden Science researchers received an NWO-XS grant for their research. Both projects are highly promising, but also high-risk. Macrophages that trap bacteria and data storage made from 2D materials convinced the board of their potential.
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European grant to research colonial medical experiments: 'Should we keep using this data?'
When we think of unethical medical experiments, we tend to think first of Nazi Germany. What is less well known is that experiments were also carried out in colonised areas without the explicit consent of the test subject. University lecturer Fenneke Sysling has received a European grant to research…
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Gerard van Westen wins KNCV Gold Medal
Gerard van Westen has received the KNCV Gold Medal, the most important Dutch award for chemists under 40. 'It's a huge honour,' says the professor of AI and medicinal chemistry. 'I am now part of the group of people I was always impressed by.'
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Multiple KHMW awards for science students
As many as seven first-year students from the Faculty of Science were honoured as young talents. In addition, the Royal Holland Society of Sciences and Humanities (KHMW) also lauded three master's students and an astronomy project during a vibrant ceremony on 28 November. Professor of Science Communication…
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The career choices of cells
How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.
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New treatments for life-threatening disease sepsis
Due to the increasing resistance to certain antibiotics, the life-threatening condition sepsis is becoming harder to treat. For her PhD project, Leiden pharmacologist Feiyan Liu used mathematical modeling to find out how antibiotics can be used more effectively to cure sepsis.
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In memoriam: Dr. Daniëlle A. Hamstra
On July 28, 2022, our dear colleague Daniëlle Hamstra passed away after a short sickbed. Daniëlle had been associated with the Clinical Psychology Section since 2010, initially as a student in the research master's program and subsequently as a lecturer and PhD candidate.
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Mental health monitor for Leiden students reveals need for more action
Last month, research by the National Institute for Public Health and the Environment (RIVM) revealed that more than half of students in higher professional education and at universities experience psychological complaints and emotional exhaustion, and that a quarter of them suffer from anhedonia (loss…
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First comprehensive study on gun violence in Europe identifies alarming trends
The steady decline in lethal gun violence in the EU came to halt in 2012 and some countries, such as Sweden, have even noticed an increase since then. An arms race among drug criminals and an increase in the availability of illegal firearms could lead to more criminal and gun violence. This is one of…
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Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.