3,451 search results for “modelling ” in the Public website
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Evolutionary diversification and historical biogeography of Orchidaceae in Central America with emphasis on Costa Rica and Panama
In this thesis, I targeted the orchid genus Lepanthes, one of the six genera of angiosperms that surpasses 1,000 species in the Neotropics, as a study model to investigate the evolutionary processes that promoted species diversifications.
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A metabolomics resistance test
Can metabolomic profiling be used to predict resistance against insect herbivores in plants?
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François Mesnard
PhD at Université de Picardie Jules Verne, Amiens - France
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The Orthodox Church in the Early Modern Middle East: Relations between the Ottoman Central Administration and the Patriarchates of Antioch, Jerusalem
This book bij Hasan Çolak is based on rigorous research on unpublished and unexplored Ottoman correspondence between the Ottoman central administration and the Eastern Patriarchates, published Greek patriarchal documents, and French missionary and diplomatic sources.
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Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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Resolving the building blocks of galaxies in space and time
We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.
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The Anthropomorphic Hegemony of Subjectivity: Critical Reflections on Law and the Question of the Animal
On 16 December 2019, Jan-Harm de Villiers defended his thesis 'The Anthropomorphic Hegemony of Subjectivity: Critical Reflections on Law and the Question of the Animal'. The doctoral research was supervised by Prof. P. Cliteur.
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Word order and information structure in Makhuwa-Enahara
This dissertation investigates the grammar of Makhuwa-Enahara, a Bantu language spoken in the north of Mozambique. The information structure is an influential factor in this language, determining the word order and the use of special conjugations known as conjoint and disjoint verb forms.
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Microfluidic 3D cell culture for high throughput screening
There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.
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Systems pharmacology of human neuroendocrine disease entities
An important hormone excreting gland in the human body is the pituitary
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Understanding the Heterogeneity of Corporate Entrepreneurship Programs
In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…
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Substances from Cradle to Grave
Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…
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Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines
Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)
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Explaining Contestation: Votes in the Council of the European Union
The researchers examine the Council of the European Union's voting behaviour between 2010 and 2021 and the impact of different independent variables.
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Enlightening the Primordial Dark Ages
This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.
- Russian Post-Soviet Diplomacy
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Laminar Technology and the Onset of the Upper Paleolithic in the Altai, Siberia
The Altai region has yielded a cluster of Middle and Upper Paleolithic stratified sites that have been recently excavated using a multidisciplinary approach.
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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The role of ceramide chain length distribution on the barrier properties of the skin lipid membranes
The skin barrier function is provided by the stratum corneum (SC). The lipids in the SC are composed of three lipid classes: ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs) which form two crystalline lamellar structures. In the present study, we investigate the effect of CER chain length…
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Science based business
The mission of science based business (SBB) connects the domains of science, business, and policy. Scientific research we focus on at Leiden in areas such as artificial intelligence promises to reshape our societies for the better. Translating science into positive societal impact however requires new…
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Chemical biology of sphingolipids: fundamental studies and clinical applications
Overkleeft
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Molecular Genetics and Biotechnology (MSc)
In the master’s specialisation Molecular Genetics and Biotechnology at Leiden University students are trained by experts in the areas of molecular biology, microbiology, plant genetics, cellular imaging, animal disease models, and various –omics technologies and the corresponding bioinformatics.
- Practical Information
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Step 4. Compare and decide
How do you decide which master's programme suits you best?
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Bioinformatics (MSc)
The master's specialisation Bioinformatics at Leiden University focuses on research, development and application of computational tools and approaches for expanding the use of biological, medical, behavioral and health data.
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Tools and data
Overview of CML software and data
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Drug Discovery and Safety (MSc)
The master's specialisation Drug Discovery and Safety at Leiden University provides students with research-oriented education into the discovery of new drug targets and new lead molecules, particularly in the field of cancer, through a combination of advanced imaging techniques (‘systems microscopy’),…
- About this minor
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Seminars
LCN2 organizes seminars on the last Friday of each month.
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Drugging the undruggable: NWO Open Competition grant for Alireza Mashaghi
Finding structure in disordered proteins and developing drugs for undruggable diseases: it might sound like mission impossible, but pharmacologist Alireza Mashaghi and his team are right on top of it. Their project was awarded by NWO through the Open Competition Domain Science -XS, a competition that…
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Special sessions
Speech Prosody 2024 includes seven special sessions. When making a submission, authors are asked to indicate whether they want their paper to be considered for a special session. You can find descriptions of each below.
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Multinationals and taxes
In the past few years, an increasing number of multinationals have made the news for large-scale use of tax planning opportunities. The Organisation for Economic Collaboration and Development (OECD) and the European Commission are studying these cases closely and investigating whether the current concepts…
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Diego Garlaschelli Group - Econophysics and Network Theory
We study the structure, dynamics and physics of complex networks emerging from the intricate interconnectedness of the constituents of large systems.
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ZF-CANCER - Developing high-throughput bioassays for human cancers in zebrafish
How can zebrafish research help to understand and fight human cancer?
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Glucocorticoid modulation of the immune response
Unraveling the immune-suppressive actions of drugs like prednisone.
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Participants
The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).
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Systems and Security
Researchers at LIACS are working to devise the computers of tomorrow that will be the backbone of the Cloud and Edge computing paradigms as well as the Internet of Things. In this respect, we are involved in research and development of high performance computing systems, embedded & real-time computing…
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Explaining Decision-Making in the European Union
Our project focuses on the analysis of decision-making processes in the European Union (EU) and explores how approaches and tools to understand decision-making found in both the Natural and the Social Sciences can be linked, knowledge between these traditions exchanged and synergies utilized. To explore…
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PhD Theses
A full overview of MCBIM PhD theses.
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Solvent effects in the electrocatalytic reactions of water
Koper
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Key publications
Key publications of the Quantitative Pharmacology group
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A piece of the Universe in the computer
Simulations of galaxies help researchers understand astronomical observations better. The EAGLE simulation, a large project in which Leiden astronomers play a leading role, shows the evolution of the Universe, from just after the Big Bang to the present day.
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Classical conditioning to improve immunotherapy in cancer
Can the conditioning paradigm be used for checkpoint inhibition cancer treatment?
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The Relativity of Statutory Provisions
Under Dutch law, like German or English law, the violation of a statutory provision does not establish civil liability for damage caused to another person. Such liability requires that the statutory provision concerned aims to protect against the damage or, put differently, that the harmed interest…
- About this minor
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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Systems and security
Researchers at LIACS are working to devise the computers of tomorrow that will be the backbone of the Cloud and Edge computing paradigms as well as the Internet of Things. In this respect, we are involved in research and development of high performance computing systems, embedded & real-time computing…
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Small Grants 2024 Research Projects
The LUCDH foster the development of new digital research by awarding a number of Small Grants each year. As in previous years the LUCDH received a large number of excellent grant applications for Research and Personal Development funds. Congratulations to the recipients of this year's research award…
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Key publications
Key publications of the Antiviral Pharmacology group.