33 search results for “gene” in the Staff website
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Advocating for gene therapies for rare diseases
‘If we don’t start talking about this, who else will?’ This is what Arjan Lankester, paediatrician/immunologist at the Leiden University Medical Center (LUMC) and Professor of Paediatrics, thought when it seemed that various extremely effective gene therapies for rare diseases would no longer be available…
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LUMC will administer first Dutch stem cell gene therapy to patients
Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…
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First patient in the Netherlands successfully treated with stem cell gene therapy
Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…
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Priyanka Chopra
Science
p.chopra@biology.leidenuniv.nl | +31 71 527 1886
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Guillermo Guerrero Egido
Science
g.guerrero.egido@biology.leidenuniv.nl | +31 71 527 4791
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Merijn de Bakker
Science
m.a.g.de.bakker@biology.leidenuniv.nl | +31 71 527 5043
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Manon de Visser
Science
m.c.de.visser@biology.leidenuniv.nl | +31 71 527 4882
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Remus Dame
Science
rtdame@chem.leidenuniv.nl | +31 71 527 5605
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Paul Hooykaas
Science
p.j.j.hooykaas@biology.leidenuniv.nl | +31 71 527 4933
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Salma Balazadeh
Science
s.balazadeh@biology.leidenuniv.nl | +31 71 527 4790
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Chao Du
Science
c.du@biology.leidenuniv.nl | +31 71 527 4947
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Felix Wittleben
Science
f.t.wittleben@liacs.leidenuniv.nl | +31 71 527 1718
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Pingtao Ding
Science
p.ding@biology.leidenuniv.nl | +31 71 527 5306
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Tom van der Wel
Science
t.van.der.wel@lic.leidenuniv.nl | +31 71 527 3534
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Breast cancer risk more accurate after genetic test
Leiden University Medical Center (LUMC) has spent the past five years coordinating an international study of genetic mutations and breast cancer risks. The results will make it easier to determine which genes increase the risk of breast cancer and to what extent. The researchers published their results…
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LUMC researchers: high levels of lipids in blood protect against allergies
People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…
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NWA grant for health law as part of NWA Cure4life
Mirjam Sombroek, Aart Hendriks and Martine de Vries (LUMC) will work on mapping the ethical and legal aspects of gene therapy. The aim is to establish a best practice of how society can best deal with these therapies. For example with guidelines on how to regulate, reimburse and make these therapies…
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‘Genetic variants could help determine whether breast cancer is hereditary’
We already know a lot about genetics and the risk of breast cancer. But much still needs to be done in breast cancer genetics to improve the prognosis and make sure women at high risk aren’t missed. This is what Professor by Special Appointment Marjanka Schmidt will say in her inaugural lecture on 4…
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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Developing new therapies to fight muscle disease
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…
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Inexhaustible source of human heart muscle cells allows strong reduction of animal testing
Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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ERC Consolidator Grants for Leiden researchers
Five Leiden researchers have been awarded a Consolidator Grant by the European Research Council (ERC). This grant of up to two million euros will enable them to continue and expand their scientific research.
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King of Sweden visits Leiden University
Collaborating in drug discovery and health research was the goal of a visit to the Leiden Bio Science Park on 14 May by a Swedish delegation including His Majesty King Carl XVI Gustav of Sweden. The delegation visited Leiden University’s Faculty of Science.
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Vici grants for three Leiden researchers
Three Leiden researchers have been awarded a prestigious Vici grant, the Dutch Research Council (NWO) announced on Tuesday. Two of the researchers work at Leiden University and the third at the Leiden University Medical Center (LUMC).
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700,000 euros for the fight against aggressive breast cancer
To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…
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New Master’s programme in Transfusion Medicine and Cellular and Tissue Therapies
LUMC and Leiden University will start the new two-year online master's program in Transfusion Medicine and Cellular and Tissue Therapies from October 2023.
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Medical Delta Professor Eline Slagboom: ‘The delta region is where everything comes together’
Professor Eline Slagboom has been studying multiple generations of families for over 20 years. She collects data on why some people age healthily and others decline early.
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Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
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Veni grants for 16 Leiden researchers
Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.
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What makes us ill?
Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…
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NWA grants for interdisciplinary consortia
Several consortia in which Leiden University is involved have been awarded Dutch Research Agenda funding. Leiden is the coordinator of five of these consortia. These five consortia will receive grants worth a total of almost 24 million euros. They relate to interdisciplinary projects that will bring…
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LIFES: From Reusable Data to New Treatments and Faster Diagnoses
Early diagnosis, new treatments, and personalised care: all of these are possible if we can better unlock the wealth of information hidden in health data. Unfortunately, this data is often poorly organised, difficult to access, and not interoperable. The new international Leiden Institute for FAIR and…