1,052 search results for “induced pluripotent system chen” in the Public website
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Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
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Chen Chen
Science
c.chen@liacs.leidenuniv.nl | +31 71 527 2727
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Yi Chen
Faculty of Humanities
y.c.chen@hum.leidenuniv.nl | +31 71 527 2727
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Chen Li
Science
cli@strw.leidenuniv.nl |
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Chen Wang
Faculteit Archeologie
c.wang@arch.leidenuniv.nl | +31 71 527 2727
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Chen Li
Science
c.li@cml.leidenuniv.nl | +31 71 527 2727
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Jinfu Chen
Science
jinfuchen@lorentz.leidenuniv.nl | +31 71 527 2727
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Bei Chen
Science
c.bei@liacs.leidenuniv.nl | +31 71 527 2727
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Xu Chen
Faculteit der Sociale Wetenschappen
x.chen@fsw.leidenuniv.nl | +31 71 527 2727
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Zhenlin Chen
Faculty of Humanities
z.chen@hum.leidenuniv.nl | +31 71 527 2125
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Yi Chen
Science
y.chen@liacs.leidenuniv.nl | +31 71 527 8920
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Yu Chen
Faculty of Humanities
x.c.chen@hum.leidenuniv.nl | +31 71 527 2727
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Ying Chen
Science
y.chen@lic.leidenuniv.nl | +31 71 527 2727
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Shaomei Chen
Faculteit Rechtsgeleerdheid
s.chen@law.leidenuniv.nl | +31 71 527 7840
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Junyuan Chen
Faculty of Humanities
j.chen@kunsten.leidenuniv.nl | +31 71 527 2727
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Wei Chen
Science
w.chen@liacs.leidenuniv.nl |
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Xing Chen
Science
chen@physics.leidenuniv.nl | +31 71 527 2727
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Zhelun Chen
Science
z.chen@math.leidenuniv.nl | +31 71 527 2727
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Yuan Chen
Science
ychen@strw.leidenuniv.nl | +31 71 527 2727
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Chen Li
Science
c.li@liacs.leidenuniv.nl | +31 71 527 7063
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Chen Tang
Science
c.tang@cml.leidenuniv.nl | +31 71 527 2727
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Qi Chen
Science
q.chen@cml.leidenuniv.nl | +31 71 527 7463
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Induced substitutions
Promotor: R. Tijdeman, Co-promotor: C. Kraaikamp
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Anisotropy, multivalency and flexibility-induced effects in colloidal systems
We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.
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Zhenyang Chen
Science
z.chen@cml.leidenuniv.nl | +31 71 527 2727
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Chen Wang
Faculteit Rechtsgeleerdheid
c.wang@law.leidenuniv.nl | +31 71 527 1571
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Rishuai Chen
Afrika-Studiecentrum
r.chen@asc.leidenuniv.nl | +31 71 527 2727
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Yiya Chen
Faculty of Humanities
yiya.chen@hum.leidenuniv.nl | +31 71 527 1688
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Jiemiao Chen
Faculteit der Sociale Wetenschappen
j.chen@fsw.leidenuniv.nl | +31 71 527 2727
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Qinyu Chen
Science
q.chen@liacs.leidenuniv.nl | +31 71 527 2727
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…
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Reverse engineering of drug induced QT(c) interval prolongation: Towards a systems pharmacology approach
Promotor: M. Danhof Co-promotor: O.E. Della Pasqua
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Chen Ji Rong Jiang
Science
c.j.r.jiang@lacdr.leidenuniv.nl | +31 71 527 2727
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Carey Ming-Li Chen
Faculteit der Sociale Wetenschappen
m.chen@cwts.leidenuniv.nl | +31 71 527 2727
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Contact-induced change in Dolgan
This study explores the role of linguistic data in the reconstruction of Dolgan (pre)history by analyzing contact-induced changes and using them to infer information about the nature of the contact settings in which they occurred.
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Advanced in vitro models for studying drug induced toxicity
Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price
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Inducing spin triplet superconductivity in a ferromagnet
Promotor: J. Aarts
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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Development of organ-on-a-chip systems for translational and personalized medicine
We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.
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Systems microscopy-based drug target discovery in pathogen-meidated inflammatory respons signalling
Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…
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SysMedPD: Systems Medicine of Mitochondrial Parkinson's Disease
The overall objective of this project is to identify novel drug candidates that are capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multimodal phenotypic characterisation of cohorts of monogenic PD…
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Unraveling the auxin mechanism in 2,4-D induced somatic embryogenesis in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa
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cellular stress pathways for mechanistic understanding of chemical-induced liver injury
Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…
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How Arabic influenced Berber, and the typology of contact-induced change
This project investigates the influence that Arabic (esp. dialectal Arabic) has had on the Berber languages of Northern Africa.
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Specificity and side-effects of mutagenesis by CRISPR/Cas9 -induced breaks in plants
Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?
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Structural changes in single chromatin fibers induced by tension and torsion
Promotor: Prof.dr. T. Schmidt, Co-promotor: Dr. ir. S. J.T. van Noort
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Threat-induced prosocial behavior: enhanced exogenous attention to protect others from harm
In a new study, we found that when we are exposed to potential harm to the other person, it improves our automatic attentional processes to avoid harm to that person.