International trade plays a critical role in global food security, with global consumption having highly localized environmental impacts.

ChEMBL is a large-scale drug discovery database containing bioactivity information primarily extracted from scientific literature.

The INTERACT project strive to unlock the enormous biotechnological potential of microbes, leading to sustainable crop productions systems.

The main research question of this thesis was: Can nitrogen cycling on dairy farms on peat soil in the Dutch Green Heart area be improved by adapting management to the nitrogen supply from soil and by using other grassland species and crops without affecting milk production?

Identifying natural plant-associated bacteria that provide targeted inhibition of pathogens through the production of antimicrobial peptides.

To explore the potential of marine microorganisms as producers of novel antimicrobial agents and as bioprotectants in aqua- and agriculture, using an integrative, ecology-based strategy for bioprospecting.

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

Farmers do not love them all. Microbes can cause tragic consequences for crops. Even the presence of just one pathogenic fungus or bacterium can drastically reduce yields. Still, there are exceptions. In that case, a pathogenic microbe is present in the soil, but does not cause any harm. Adam Ossowicki…

Did early farmers deliberately use animal manure on their fields?

We investigate bacteria and fungi to understand their malicious or beneficial impact on food crops and their pathogenic or antibiotic role in human health.

A jar, filled with water, that functions as an aquarium for fishes while plants or flowers grow on top. Urban Crops, a young start-up company, creates small eco-systems in jars by using aquaponic systems. The 'Ecojar' is a modern decoration in living-rooms and office spaces, but also purifies the air…

Dr. Kirsten Leiss and Prof. Peter Klinkhamer received 900.000 euro’s from “Stichting Toegepaste Wetenschappen (STW)” and the company “Rijk Zwaan” to develop plants that are resistant to thrips, a major agricultural pest all over the world.

What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?

Information about the products of the extract library.

Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…

Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong

Steering soil microbiomes for better crop quality: the holy grail to improve human health?

Welcome to the Dutch Extract Library, the library of the majority of crop extracts grown in Dutch horticulture.

“JARAK: the commoditization of an alternative biofuel crop in Indonesia” was a research program from 2010-2014 in which researchers from Indonesia and the Netherlands collaborated.

Agrian History, 5300 BC - AD 1000; C.C. Bakels

Since the adoption of agriculture people have cultivated fields. The project concerns all kinds of aspects related to raising crops.

Archaeobotanic research by prof. dr. C. Bakels and students on agriculture.

How can we make agricultural production systems more sustainable as the worldwide demand for healthy, safe food continues to grow? How can we develop healthy new food crops that have higher yields while requiring fewer harmful chemicals?

Charisma K. Lepcha (PI, Sikkim University), Pradyut Guha (co-PI, Sikkim University), Rajib Sutradhar (co-PI, Christ University Bangalore) and Erik de Maaker (Leiden University) have been awarded a two-year grant of USD 18.000 to conduct research on the impact of ‘green farming’ on the sensitive mountain…

A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh

Natural product library for high throughput screening.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

The role of domestic and wild resource exploitation in Bronze Age subsistence

Microbes influence and respond to other organisms. This theme explores the dynamic relationships within plant and animal microbiomes, and the immune responses that govern host defense. Using model systems such as zebrafish, insects, and plants, we investigate fundamental processes and engineer microbes…

What are key regulators of plant ageing that can reverse ageing in plants (rejuvenation), and how can we use this knowledge to improve crop plants?

In this dossier you can read about Leiden University’s commitment to sustainability.

Increasing above- and belowground biodiversity in arable leek cultivation to stimulate pest control by natural enemies.

How do plant defense genes get activated?

An environmental and palaeo-economic reconstruction.

This project explores the decline of shifting cultivation in Northeast India. What is the impact on society of people’s deepening engagement with markets and the state?

Living systems scale from unicellular microbes to complex multispecies communities that constantly change over time. Within the theme Development & Disease, we enhance our fundamental understanding of development and homeostasis of living cells and systems. We analyze the normal situation and how stresses…

The mission of the Plant Sciences cluster is to contribute to the sustainable production of high-quality crops, flowers and high-value bio-based products, and to contribute to the maintenance and restoration of biodiversity in natural ecosystems. This is realised by generating fundamental knowledge…

best phd theses of the faculty of science Leiden - physics, chemistry, computer science, biopharmaceutical sciences, biology, industrial ecology, environmental sciences, astronomy, mathematics. thesis