869 search results for “electron microscopy” in the Public website
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Microfluidic 3D cell culture for high throughput screening
There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.
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Towards artificial photosynthesis on the lipid bilayer of liposomes
Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.
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Parkinson’s protein α-synuclein: membrane interactions and fibril structure
The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.
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Milan Allan Lab - Understanding Quantum Matter
We are a dynamic research group at the Leiden Institute of Physics. Our aim is to explore and understand quantum materials, including strange metals, high-temperature superconductors, and quantum critical electron matter.
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Leiden University strengthens its focus on Chemical Biology and Medicinal Chemistry with seven new group leaders
Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…
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How NeCEN helped develop the Johnson & Johnson Covid-19 vaccine
The Phase 3 clinical trial results of the promising Covid-19 vaccine of Johnson & Johnson are expected this month. The Dutch electron microscopy facility NeCEN helped develop the company’s vaccine, and they have now published their scientific findings in Nature Communications.
- Jan van Ruitenbeek Lab - Atomic and Molecular Conductors
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ERC grants for four Leiden scientists
Four scientists from Leiden University have each been awarded a Starting Grant by the European Research Council (ERC). This grant, worth up to two million euros, gives researchers the opportunity to head up a research team for five years.
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Solution to distortion effect STM scanning
STM scanning experiments on poorly conducting materials are challenging, and can cause a distortion effect. A new model corrects for this effect, allowing physicists to better study materials in their quest to understand unconventional superconductivity. Publication in Physical Review B as Editor’s…
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Winner Physics Image Award is Volkskrant Image of the Week
Vera Meester has won the annual Physics Image Award 2016, with her photo of 'smiling' colloids. The Volkskrant published the picture as Image of the Week.
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Spin-label EPR Approaches to Protein Interactions
Promotor: Prof.dr. E.J.J. Groenen
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Bachelor Projects
Bachelor projects are available in
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Leiden research project on circular electronics receives 3.8 million euros from NWO
Fewer CO2 emissions, less airborne viral transmission, and a more sustainable form of food production: seven consortia of researchers and societal partners will put a budget of 32 million euros towards developing technological innovations. Important Leiden research on circular electronics by Prof. Dr.…
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Charge transport properties of Ru-complex molecules: the influence of humidity
I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.
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Between air and electricity : microphones and loudspeakers as musical instruments
This thesis investigated how microphones and loudspeakers could become musical instruments.
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The Chara plasma membrane system : an ancestral model for plasma membrane transport in plant cells
Multicellular giant algae Chara species have been widely used in physiological studies for decades.
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New technique for Imaging Charge Transport in a Graphene Layered Cake
Leiden Physicists have developed a new technique to visualize electrical conductance in sheet-like nano materials. It shows great promise for devices based on a new family of materials—the ‘Van der Waals materials’. The physicists, who won the 2015 Dutch Vacuum Society prize for their work, present…
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Leiden Physics hosts 2016 NEVAC day
The Leiden Institute of Physics hosted the annual conference of the Dutch Vacuum Society (NEVAC). Experts in the field of vacuum experiments talked about their research. The 2016 NEVAC Prize was awarded to PhD student Martijn Vos from the TU Eindhoven.
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Setup: Static Magnetic Field with Low Noise
Our cantilevers have a low intrinsic damping rate: this enables us to measure with low noise, since damping is proportionate to noise. However, when the magnet is close to the surface of a sample we want to study, we measure a much higher effective damping rate. This is caused by magnetic interaction…
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Mayor of Leiden visits NeCEN
Last Monday April 18, Bram Koster (professor at the Institute of Biology Leiden (IBL), professor at the Leiden University Medical Center (LUMC)) and Ariane Briegel (professor at the IBL) gave a presentation to the mayor of Leiden, Henri Lenferink. The presentation took place at NeCEN, the open access…
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Mapping of bacterial genomes to combat infectious diseases
Mapping of bacterial genomes to combat infectious diseases
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New SAILS lunch series in 2021
In 2021 we will start with a weekly lunch time seminar series, online on Mondays from 12 noon onwards.
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The origins of friction and the growth of graphene, investigated at the atomic scale
Promotor: J.W.M. Frenken
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Multiple Paths. Towards a Performance Practice in Computer Music
This thesis proposes multiple paths towards the development of a performance practice in Computer Music.
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The Musical Work, Free Improvisation, and Live Electronics: Towards an Integrated Musical Paradigm.
Composer, bass player and ACPA alumnus Ilya Ziblat Shay presented a paper at the Music Weekend and Midlands New Music Symposium, organised by Nottingham Forum for Artistic Research.
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Fermions and Bosons: Excitons in strongly correlated materials
Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp
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The heart of oxygenic photosynthesis illuminated
Promotor: H.J.M. de Groot, Co-Promotor: A. Alia
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Mighty microscopy
Festival
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Unfolding secrets of catalysts
To construct catalysts that can produce fuels from CO2 innumerable times, we need to learn much more about how catalysis works. Irene Groot is conducting groundbreaking research into catalysis at the atomic level.
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Medical Delta professor Ariane Briegel: 'I love working with people from different backgrounds'
Multidrug-resistant pathogens and worldwide pandemics are increasing, making infectious diseases more prevalent. To develop new treatments, deeper knowledge of the interaction between bacteria and human cells is required. Ariane Briegel recently became a Medical Delta professor and studies such path…
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Sense Jan van der Molen appointed as Professor Physics of Condensed Matter
As of 1 June, Leiden University has appointed Sense Jan van der Molen as Professor Physics of Condensed matter. He investigates the unique electronic properties that arise when atomic thin layers are stacked on top of each other into new materials.
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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Environmental and health impact of informal e-waste recycling
The majority (80%) of e-waste generated globally are recycled informally in developing countries.
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Cryo-EM of cholera infection
The structure of bacterial cells provides crucial clues about their interaction with their host. What are the key structural features of a bacterial cell that determine pathogenicity? What roles do these structures play in the life cycle, and how do they change during the infection process?
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Prof. Marin van Heel awarded Wiley Prize in Biomedical Sciences 2017
Prof. Dr. Ir. Marin van Heel, Emeritus Professor at the Institute of Biology Leiden (NeCEN), is one of the winners of the “Wiley Prize in Biomedical Sciences 2017”. This annual award is presented to recognize contributions that have opened new fields of research or have advanced concepts in a particular…
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Understanding the Surface Structure of Catalysts and 2D Materials at the Atomic Scale
The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.
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Training and courses
There are several training oportunities within the cell observatory
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Expertise
The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine. The available expertise extends…
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NWA grant for research into iron nanoparticles in the brain
Physicists Lucia Bossoni and Martina Huber have been awarded an NWA Ideeëngenerator-grant for research into iron nanoparticles in the brain. These nanoparticles may be linked to air pollution and Alzheimer's disease.
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Nose of E. coli zips open and shut
PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.
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New method of detecting rapid virus development
Physicists, including Leiden researcher, Sanli Faes, have devised a new technique for studying processes at microscale rapidly and extremely precisely. This new method will make it easier to develop antiviral medication. And it doesn’t stop there. Publication in ACS Nano.
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Vidi research grant for physicist Daniela Kraft
The image of the Leiden microboat traveled all over the world, from the BBC up to Arab shipping blogs. But Daniela Kraft's research group has quite a few more different 3D printed microswimmers up their sleeves. Kraft receives a Vidi research grant for research into these variously shaped active par…
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Mazène Hochane and Xueying Fan win LION Image Award 2018
Mazène Hochane and Xueying Fan have won the fourth annual LION Image Award. They created a detailed colour image of a human kidney in development.
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Unraveling the mechanism of multicopper oxidases: from ensemble to single molecule
Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma
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Paradox in superconductivity at high temperature
Nature publishes an article on a paradoxical discovery in superconductivity. Physicists are searching for superconductivity at high temperatures so that less cooling is needed in for example MRI machines. News & Views article by Prof. Jan Zaanen in the same issue of August 19th.
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Explorations of Water Oxidation Catalysis in Explicit Solvent
In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.
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Abolfazl Sajadi
Science
a.sajadi@liacs.leidenuniv.nl | +31 71 527 4799
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Merijn de Bakker
Science
m.a.g.de.bakker@biology.leidenuniv.nl | +31 71 527 5043
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Daniel Vale
Faculteit Rechtsgeleerdheid
d.s.vale@law.leidenuniv.nl | +31 71 527 8838