748 search results for “electron microscopy” in the Public website
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Research
Combining different disciplines, researchers work together to formulate innovative solutions to societal problems.
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COVID-19 vaccine
Leiden researchers are helping develop safe COVID-19 vaccines.
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Self-assembly properties and applications of metal-binding peptides and proteins
It is estimated that approximately 30% of all proteins require a metal to function. Investigating the relationship between metal-binding and peptide/protein folding allows us to uncover fundamental rules for creating metallo-peptides and proteins, which in turn leads to the creation of new structures,…
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New imaging technology to assess early drug success
Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…
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Life Sciences Café visits NeCEN
On 21 March The Netherlands Centre for Electron Nanoscopy (NeCEN) hosted the Life Sciences Café. Around 60 people from neighbour companies from the Leiden BioScience Park visited the facility for cryo-electron microscopy to get a glimpse behind the scenes. Head of NeCEN Ludo Renault believes it was…
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Electrons found to flow like water
Science Magazine has published three back-to-back papers on an important discovery in solid state physics. Leiden physicist Jan Zaanen wrote a Perspective article on the subject in the same issue of 4 March.
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A clear picture of bacteria
Freezing bacteria super fast to gain a true-to-nature image of the internal and external structure. Ariane Briegel Professor of Ultrastructural Biology came to Leiden specially to carry out this research. Leiden University is one of the few institutes in the world to have the necessary equipment. Inaugural…
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Imaging complex model catalysts in action
From surface science towards industrial practice using high-pressure scanning tunneling microscopy.
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Joining hands to advance Dutch microscopy
Advanced microscopy to understand life and fight disease: that’s the goal of the new NL-BioImaging network that will develop and integrate state-of-the-art microscopy technologies and services. Researchers from all Dutch universities, including Leiden University and the Leiden University Medical Centre,…
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Joan van der Waals colloquium
The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.
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Surface and Interface Science
The nanoscale structure of a catalyst under reaction conditions determines its activity, selectivity, and stability. For the production of sustainable energy and materials, new catalysts are needed. By understanding the structure-activity relationships of catalysts under reaction conditions, insight…
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Monitoring and detection of nanomaterials in biological media.
How do nanoparticles bioaccumulate and biodistribute in organisms?
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Ten million euros for unlocking novel technologies in structural biology
The European Union has invested ten million euros in the so-called iNEXT-Discovery consortium. The goal of this new consortium is to enable European researchers to extend innovative structural biology research. The Netherlands Centre for Electron Nanoscopy (NeCEN) is also part of iNEXT-Disovery, which…
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Elena Egorova
Science
e.a.egorova@lic.leidenuniv.nl | +31 71 527 4234
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ZF-HEALTH - Zebrafish Regulomics for Human Health
How can zebrafish research help understanding human diseases?
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Institute of Biology
Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’
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Developing new therapies to fight muscle disease
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…
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Thousands of images of frozen bacteria
How do bacteria sense and adapt to their environment? Ariane Briegel, Professor of Ultrastructural Biology, is intrigued by this question. Using new techniques, she produces three-dimensional images of bacteria that provide us with new clues about their sensory system.
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Meiru Wang
Science
m.wang@cml.leidenuniv.nl | +31 71 527 2727
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New ONEM Microscope to combine best of two worlds
Leiden physicists have been awarded 1.5 million euros for developing a hybrid microscope that provided nanometer-resolution. 'The idea is to combine the resolution of electron microscopy with the pros of optical microscopes.'
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Harmonic duality : from interval ratios and pitch distance to spectra and sensory dissonance
This dissertation derives from the development of tools for algorithmic composition which extract pitch materials from sound signals, analyzing them according to their timbral and harmonic properties, putting them into motion through diverse rhythmic and textural procedures.
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Quantitative live cell imaging of glucocorticoid receptor dynamics in the nucleus
In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.
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Gorlaeus Building Tour
The doors of the new Gorlaeus Building are officially open! With an additional lab wing, new lecture halls and offices, a library, a brasserie, and spaces for student associations, the building offers a vibrant and inspiring environment for research, study, and social interaction. Explore on your…
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Atomic Insights into Hydrodesulfurization
Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.
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Core Facilities
Core Facilities are shared resources that provide access to instruments, technologies and services to researchers across the Institute of Biology. They are staffed by scientists with vast experience in their field, ensuring that all researchers can count not only on the latest available technology…
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Briegel winner in global competition by the Moore Foundation
Ariane Briegel, Professor of Ultrastructural biology in Leiden, has received a prestigious incentive from the Gordon and Betty Moore Foundation. With the grant of 800,000 euros, Briegel will set up a new research line into studying symbiotic interactions on the nanoscale.
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Ratification of High Troughput Microscopy Dutch Flagship Node as Euro-BioImaging Node Candidate
The High Troughput Microscopy Dutch Flagship Node that includes the Leiden Cell Observatory Screening platform is now officially ratified as a Euro-BioImaging (EuBI) Node Candidate
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Frontiers of Modern Physics
This is the physics summer school of Leiden University. It is part of the Leiden Institute of Physics (LION). The summer school is intended for Bachelor (BSc) students in physics. It covers topics from quantum matter and optics, to biological & soft matter physics and cosmology and theoretical physics.…
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Leiden physicists meet Nobel prize winners
Two Leiden physicists took part in the Lindau conference in Germany from 26 June to 1 July. They met Nobel prize winners from their field.
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New funding for advanced microscopy using gold nanorods
A consortium of researchers from the Leiden Institute of Physics (LION), the Institute of Biology Leiden (IBL), and the Leiden Institute of Chemistry (LIC) received a FOM program grant to develop a novel way of studying individual proteins inside a cell using gold nanorods.
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Marie Guilleray-Guénanff
Faculty of Humanities
m.f.a.guilleray-guenanff@kunsten.leidenuniv.nl | +31 71 527 2999
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Renewable Energy
The transition to new and renewable energy sources should be completed by 2050. Researchers in various disciplines at Leiden University are conducting unique research that will help us make this transition and reduce CO2 emissions.
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European project ImageInLife has started
The Horizon 2020 project ImageInLife has started on 1 January, followed by a kick-off meeting at the coordinating University of Montpellier at the end this month. This Marie Skłodowska-Curie training network brings together European groups that work on the imaging of vertebrates and offers fourteen…
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Why Leiden University?
The Physics and Quantum Matter and Optics specialisation is one of the two programmes Leiden offers in experimental physics. The programme can be tailored to individual needs and interests.
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Third annual Physics Science Day
On Tuesday September 11th, the Leiden Institute of Physics (LION) organizes the third edition of its annual Science Day. Scientists from disciplines all across the physics spectrum will elaborate on their research during seventeen interactive talks. LION organizes the event to showcase the full range…
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for the beauty of physics
Leiden Physics Poster
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Delegation from Czech research center visits Leiden’s Faculty of Science
On 3 and 4 June 2015 a delegation from the biotechnology and biomedicine center in Prague (BIOCEV) visited the Faculty of Science in Leiden, as well as the Netherlands Centre for Electron Microscopy (NeCEN). The delegation was interested to see the potential for collaboration in the field of cryo transmission…
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Hit and Lead Optimization
The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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Colloquium: Imaging Electrochemical Reactions by Operando Optical Microscopy
Lecture
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Microfluidic 3D cell culture for high throughput screening
There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.
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Invited speakers
Speakers that have accepted to participate:
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Towards artificial photosynthesis on the lipid bilayer of liposomes
Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.
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Milan Allan Lab - Understanding Quantum Matter
We are a dynamic research group at the Leiden Institute of Physics. Our aim is to explore and understand quantum materials, including strange metals, high-temperature superconductors, and quantum critical electron matter.
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Parkinson’s protein α-synuclein: membrane interactions and fibril structure
The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.
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Leiden University strengthens its focus on Chemical Biology and Medicinal Chemistry with seven new group leaders
Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…
- Jan van Ruitenbeek Lab - Atomic and Molecular Conductors
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ERC grants for four Leiden scientists
Four scientists from Leiden University have each been awarded a Starting Grant by the European Research Council (ERC). This grant, worth up to two million euros, gives researchers the opportunity to head up a research team for five years.
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Winner Physics Image Award is Volkskrant Image of the Week
Vera Meester has won the annual Physics Image Award 2016, with her photo of 'smiling' colloids. The Volkskrant published the picture as Image of the Week.
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Bachelor Projects
Bachelor projects are available in