485 search results for “single molecule spectroscopy” in the Staff website
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Zware metalen hebben slechte reputatie, maar genezen ook kanker
Veel mensen denken dat zware metalen giftig zijn en mens en natuur altijd schade aanbrengen. Dat beeld moet genuanceerd worden, vindt hoogleraar Sylvestre Bonnet.
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Artificial intelligence as the co-pilot for drug discovery
There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…
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Countering nerve pain caused by chemotherapy with new drug
Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…
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Understanding superconductivity comes closer with major ERC grant for Milan Allan
Physicist Milan Allan will build an instrument that will bring superconductivity research further. He has been awarded an ERC Consolidator Grant of 2 million euros over the next five years. With his PairNoise programme he aims to detect paired electrons as they occur just above the temperature at which…
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Antibiotic resistance: an economic problem universities could help to solve
Antibiotic resistance is an economic problem. Pharmaceutical companies cannot earn much from antibiotic research, so they do not invest in it. This makes it important that universities do so, says Ned Buijs.
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This is how physicists use light to build complex structures
Petr Steindl works on quantum dots in microcavities for his PhD research. He manipulates single-photons to create complex structures of light. Applications could include quantum communication and gates for quantum computers.
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Nobel Prize winner visited Leiden: 'We have hosted a scientific rockstar'
On 28 September the famous chemists Carolyn Bertozzi visited Leiden University to speak at the LED3 seminar. Just one week later, she was announced winner the 2022 Nobel Prize in Chemistry. Leiden chemists Sebastian Pomplun and Hermen Overkleeft are fan: ‘We are extremely honoured to have hosted this…
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Webb reveals chemical profile of atmosphere of exoplanet WASP-39 b
An international team of astronomers has revealed the first 'chemical profile' of an exoplanet's atmosphere. The team, including Leiden astronomer Yamila Miguel and provenda Amy Louca, made the profile using so-called Early Release Science data from the James Webb Space Telescope. The results have been…
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From bachelor student to entrepreneur: card game about elementary particles an unexpected hit
bachelorstudent Serafine Beugelink ontwikkelt kaartspel over elementaire deeltjes en deeltjesfysica. Ze zet succescol haar eigen bedrijf op.
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Gaia sees strange stars in most detailed Milky Way survey to date
Today, ESA’s Gaia mission releases its new treasure trove of data about our home galaxy. Astronomers, led by the Leiden astronomer Anthony Brown, describe strange ‘starquakes’, stellar DNA, asymmetric motions and other fascinating insights in this most detailed Milky Way survey to date.
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Dag van de duurzaamheid: Launch Billiecup
Op de dag van de duurzaamheid van 10 oktober startte de 'Billiecup' pre-pilot op de Faculteit der Rechtsgeleerdheid. Aanwezig waren 'plastic soup surfer' Merijn Tinga, Bart Hemmes van het Leiden University Green Office (LUGO) en Esther Kentin, docent bij instituut Metajuridica & projectleider Leiden…
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Webb detects icy ingredients for making potential habitable worlds
An international team of astronomers, led by Will Rocha of Leiden Observatory, using the NASA/ESA/CSA James Webb Space Telescope have discovered that the key ingredients for making potentially habitable worlds are present in early-stage protostars, where planets have not yet formed.
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Status update in the evolutionary race between humans and resistant bacteria: two steps forward for us
A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…
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Planet-forming discs around young low-mass star differs fundamentally from one around sun-like star
Using the James Webb Space Telescope, an international team of researchers, including Leiden Professor of Molecular Astrophysics Ewine van Dishoeck, has discovered a palette of hydrocarbons in a planet-forming disc around a young, low-mass star. The results confirm that discs around very lightweight…
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Kilometre allowance
You are entitled to apply for a regular or supplementary kilometre allowance for commuting days based on the Terms of Employment Individual Choices Model. You will not be reimbursed for the total amount of your commuting expenses, but by using your gross income you will benefit from tax advantages.
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Phishing
We all occasionally receive an email from an unknown sender, with content we weren’t expecting or that raises our suspicions in some other way. This is usually a fake email, also known as a phishing email. In fact, there are various types of phishing: it can also be done over the phone.
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University introduces lay talk and it looks like this
Complex research with a generous sprinkling of jargon: PhD defences can be difficult for non-experts to follow. In the compulsory new lay talk, PhD candidates begin by explaining their dissertation in words of one syllable. And it’s not just the PhD’s family and friends who appreciate this.
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Super-Earth Atmospheres
PhD defence
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Chemotherapy without side effects? It’s possible, with light
Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.
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Astronomers spot benzene in planet-forming disk around star for first time
An international team of astronomers including Leiden professor Ewine van Dishoeck has observed the benzene molecule (C6H6) in a planet-forming disk around a young star for the first time. The observations tell us more about the forming of planets in this disc, like our own Earth. The scientists publish…
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Improving nature’s antibiotic
'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…
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More efforts for less waste: reusable crockery will become standard
Facility
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Bioengineering and Biophysics of Viral Hemorrhagic Fever
PhD defence
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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How a pathogenic bacterium searches for food
Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.
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Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
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How bittersweet sugar chemistry targets pathogens
The challenge is considerable, but so is the satisfaction when it succeeds: creating complex sugar molecules that play a role in biology.
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A foldable smartphone? STIBNITE searched for the perfect semiconductor
Roll-up solar panels, bendable phone displays, or better computer chips… The EU project STIBNITE investigated the next generation of semiconductors, made from organic materials based on carbon, nitrogen, and boron. The project has now concluded. During the Open Science Debate on 1 July, the group will…
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Investigating inflammation: new leads for treating atherosclerosis
How do you detect people at high risk of heart attacks and strokes? And how can we improve the treatment of atherosclerosis? These are the questions that keep LACDR researcher Marie Depuydt busy. She is investigating the immune cells that contribute to the worsening of atherosclerosis. ‘It's a challenging…
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Rubicon grant for Remko Fermin: superconducting diodes for energy-efficient data centres
Physicist Remko Fermin from Leiden University was awarded a Rubicon grant from NWO. He will use it to study superconducting diodes that could contribute to reducing the CO2 emission of data centres.
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What if superbugs were as tall as buildings?
In Sci-Fi comic book Resist NOW!, wondrous adventures will illustrate possibilities to combat antimicrobial resistance. But the comic book will only be produced if enough money is raised to make the project into reality.
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Webb data suggest potential atmosphere around rocky exoplanet
Researchers using NASA’s James Webb Space Telescope may have detected atmospheric gases surrounding 55 Cancri e, a hot rocky exoplanet 41 light-years from Earth. This is the best evidence to date for the existence of any rocky planet atmosphere outside our solar system.
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3D-printed mini-tumours: a leap forward in improving cancer immunotherapy
Leiden researchers have developed a groundbreaking model to advance cancer immunotherapy. Using a 3D printer, they create mini-tumors within an environment that closely mimics human tissue. They have also developed a method to monitor real-time interactions of these mini-tumours with immune cells during…
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From Remindo to ANS: Faculty of Humanities implements a new assessment system
The Faculty of Humanities will introduce a new assessment system in the next academic year. Marcel van Brunschot, the project leader for the digital assessment migration, is responsible for overseeing the transition to ANS.
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Diversify ARCHaeology Fund: Call for Applications for 2024-2025
Facility
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The career choices of cells
How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.
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€10.6 million for innovative toolboxes to tackle brain cancer
Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…
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LIC Lecture + drinks
Lecture
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Using low sample volumes to better understand brain diseases
Marlien van Mever delved into the analysis of tiny samples, cerebrospinal fluid from transgenic mouse models for example. She validated methods that can now be used to study brain diseases such as migraine and epilepsy. Van Mever will receive her PhD on 14 June.
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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From discovery to business: 'In the lab, we often don't realise that we are working to help an immense number of patients'
'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…
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First detailed picture of ice in planet-forming disk
An international team of astronomers led by Ardjan Sturm of the Observatory has made the first two-dimensional inventory of ice in a planet-forming disk of dust and gas surrounding a young star. The researches, including Melissa McClure, used the James Webb Space Telescope and publish their findings…
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From droplets in the freezer to the inception of a potent new antibiotic
What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…
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In Memoriam - Joan van der Waals
On 21 June, our beloved colleague Joan van der Waals passed away after a long and rewarding life.
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A look behind the scenes at the Leiden Science Family Day
More than 700 visitors got to know the Science Faculty during the Leiden Science Family Day. People of all ages could enjoy fascinating experiments, tours, interesting lectures, spectacular nitrogen shows and various workshops. It was an informative day with many (future) scientists, amazement and,…
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'If you think astronomy is a man's world, then it's your job to make a change'
During her master's thesis, Nashanty Brunken (24) worked in a team with five other women. With this female team, they discovered the largest molecule so far identified in a disc. 'I have learned so much and because we are all women, it is incredibly empowering. It's very cool to see how far we've come…
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Archaeologists Involved in Ambitious Study on Past Land Use
To increase the accuracy of climate models, it is crucial that they include past human land-use and human-driven vegetation changes. Here archaeology can make an important contribution. Current models are based on reconstructions of past vegetation. However, their accuracy is limited because it does…
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Leiden researchers receive Ig Nobel Prize for research into romantic click
Cognitive psychologists Eliska Prochazkova and Mariska Kret from Leiden University have won an Ig Nobel Prize for their research into the romantic click between people. They discovered that attraction between people can be predicted by synchrony in heart rate and skin conductance.
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Less plastic in university restaurants
Facility
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In Memoriam: Robert Louw 1936-2023
On 18 February 2023, our esteemed former colleague Robert Louw passed away. Rob was 86 years old.