Research

For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…

In prehistoric times there was a huge wave of migration, from the steppes in Russia and Ukraine to West Europe. The newcomers’ genes began to dominate. Archaeology research in Leiden into burial mounds in the Veluwe and Utrechtse Heuvelrug areas of the Netherlands yielded this spectacular conclusion.…

PhD candidate Mengxu Zhang (Division of Systems Pharmacology and Pharmacy) published a comprehensive and important review on “The potential impact of CYP and UGT drug-metabolizing enzymes on brain target site drug exposure” in Drug Metabolism Reviews.

Marieke Liem, professor at ISGA, discusses how the number of drug-related murders has not decreased in the last years

Drug use during pregnancy seems like a choice without any consequences. However, the Dutch Public Prosecution Service (OM) has decided to prosecute a mother for using alcohol and drugs during her pregnancy. Mariëlle Bruning, Professor of Child Law, tells current affairs programme ‘Nieuwsuur’ that she…

The Lorentz Center is a melting pot that is visited by researchers from around the world. ‘Miracles happen’ during the five-day interactive workshops at the Center. And there is an extra reason to celebrate the center’s 25th anniversary. On 28 April, the Dutch Research Council (NWO) and Leiden University…

In a recent article published on PLOS, Drs. Briana Pobiner and Ryan McRae of the Smithsonian Institution National Museum of Natural History discuss the top 13 discoveries in human evolution in 2023.

Research

The Lorentz Center is 25 years old. A good reason for them to contribute to a series of TEDx lectures for Leiden City of Science. Arjen Doelman, director of the Lorentz Center, was the first to enter the virtual stage.

Prof. Ton Liefaard and Chrisje Sandelowsky-Bosman visited Curaçao to launch de Caribbean Center for Children’s Rights and present research.

Archaeologist Bjørn Peare Barthold suspected farmers in a doctorless 19th century Dutch village may have been self-medicating to manage pain and disease. By examining the skeletons' dental calculus this hypothesis could be tested. Science Magazine interviewed him about this new technique.

How can the people of Leiden age as well as possible? And what is needed to reduce health disparities? That is the mission of Leiden Healthy Society Center, a new partnership between the Municipality of Leiden, Leiden University and many other partners in the city.

Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.

Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’

From time to time, manuscripts that have remained hidden for centuries turn up in library collections and archives. In the archives of the 17th-century Bibliotheca Thysiana at the Rapenburg in Leiden, kept in the Leiden University Library, Rotterdam researcher Erik-Jan Bos discovered a hitherto unknown…

Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.

In dermatology, there should be a high level of multidisciplinary collaboration among institutes and specialists, Professor of Translational Dermatology, Robert Rissmann, will say in his inaugural lecture on 8 July. He is building an infrastructure that will put pre-clinical and clinical skin research…

As coordinator and lead promoter respectively of the Leiden Healthy Society Center, psychologists Sandra van Dijk and Anke Klein use interdisciplinary collaboration to resolve the major health problems of the present day. How are they going to do that in the coming period?

With a €1.5 million European grant, industrial ecologist Stefano Cucurachi will work on more sustainable production methods for the pharmaceutical industry. The Italian company Angelini Pharma intends to use the resulting knowledge to make its production process more sustainable.

‘’ And then the world changed forever ,welcome to the future’’. These are the words that Kausik Ray (President of the European Atherosclerosis Society) spoke when the worldwide first dose of inclisiran, a novel SiRNA based cholesterol lowering agent, was administered at the Cardiology lipid clinic at…

The fifteenth Annual Convention of Austria Centers took place in Berkeley, California, USA in May 2023.

The sixteenth Annual Convention of Austria Centers took place in Budapest, Hungary in June 2024. There, colleagues gathered from around the world, coming from Jerusalem, Olomouc, Vienna, Berkeley, Edmonton, Minneapolis, New Orleans, Budapest and, of course, Leiden.

Four university medical centres, including the LUMC, are joining forces to increase pandemic preparedness in the Netherlands.

PhD defence

Academic writing: it’s something that all students have to face. And it can be really quite difficult. The writing coaches at the Humanities Writing Center will therefore support you at every stage of your studies.

With his essay 'Why science?', mathematics prodigy Lars Pos (18) won the Robbert Dijkgraaf Essay Prize. Within the theme 'The fascinating workings of science', the bachelor student wrote a plea for the societal value of fundamental scientific research. 'Because you don’t know beforehand where we can…

Lecture

Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…

Two directors. Both professors of mathematics, but one of them is a biologist. One comes, and the other goes. Roeland Merks will succeed Arjen Doelman as director of the Lorentz Center in September. What has been accomplished and what are the plans? And above all, what makes the Lorentz Center so un…

Research

Network meeting

This March, Jara Bouma, Cas van der Horst and Laura Heitman from the Division of Drug Discovery and Safety and Laura de Paus, Richard van den Berg, Anthe Janssen and Mario van der Stelt from the LIC joined forces to determine how some drugs can specifically target the cannabinoid CB2 receptor (CB2R)…

Training for staff members

PhD defence

PhD defence

PhD defence

Do you recall all those drugs that were hastily proposed as potential treatments for COVID-19? In the event of a future pandemic, the goal is to offer an effective treatment more quickly and efficiently. To achieve this, a team led by Coen van Hasselt is developing a platform that can speed up the process…

The Ministry of Health, Welfare and Sport (VWS) submitted Pharma-NL to the R&D program of the National Growth Fund, a 20 billion euro program of the Dutch government that intends to create long-term economic growth in The Netherlands.

The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?

Matchmaking event

A cancer pill, preferably without severe side effects, is something we’d all welcome. Is it a matter of time before such a pill is a reality? We put this question to three Leiden researchers and asked how they themselves are contributing to new cancer treatments.

Lecture, Tuesday Talks: Science Insights

Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…