381 search results for “cryo-electron microscopy” in the Public website
-
Vibration Isolation
To be able to measure small forces or small deviations from Boltzmann, the external vibrations at the resonance frequency must be very low. To achieve this, we have developed a very soft vibration isolation system and combine it with several other measures to reduce vibrations in our dilution refrigerators.…
-
Solid State NMR and modelling of photoinduced energy and electron transfer
Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…
- Jan van Ruitenbeek Lab - Atomic and Molecular Conductors
-
Research
An overview of the research at the Cancer Dug Target Discovery group.
-
Personal ornaments: changing identities in the Dutch Neolithic and Bronze Age
Numerous beads and pendants of amber, jet and bone have been found in Dutch Neolithic and Bronze Age context, both in settlements and in graves. Because ornaments are personal items, they are closely linked with people’s identity.
-
Ariane Briegel: 'AI literally opens new worlds for the life sciences'
Bacteria caught red-handed, deeply frozen just as they were about to cause Lyme’s disease. Ariane Briegel is wildly enthusiastic about the wonders she observes thanks to three elements: a freezing technique, a camera-equipped microscope, and AI. ‘It’s fascinating. Every single cell is different.’
-
Research
Combining different disciplines, researchers work together to formulate innovative solutions to societal problems.
-
COVID-19 vaccine
Leiden researchers are helping develop safe COVID-19 vaccines.
-
Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
-
Cell Observatory: visualising structures of life
From molecule, to cell, to organism. The high-level drug research at the Cell Observatory aimes at reducing the spread of cancer and developing new medicines for tuberculosis.
-
Self-assembly properties and applications of metal-binding peptides and proteins
It is estimated that approximately 30% of all proteins require a metal to function. Investigating the relationship between metal-binding and peptide/protein folding allows us to uncover fundamental rules for creating metallo-peptides and proteins, which in turn leads to the creation of new structures,…
-
Cancer Drug Target Discovery
We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.
-
Functions of autophagy in the filamentous fungus Aspergillus niger
What are the functions of autophagy in the filamentous fungus Aspergillus niger?
-
OMERO
From the microscope to publication, OMERO handles all your images in a secure central repository. You can view, organize, analyze and share your data from anywhere you have internet access. Work with your images from a desktop app (Windows, Mac or Linux), from the web or from 3rd party software. Over…
-
Bachelor Projects
Bachelor projects are available in
-
New imaging technology to assess early drug success
Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…
-
Imaging & Intervention (MSc)
This specialisation focuses on two important trends in health care: early diagnosis and developing the most targeted patient-specific treatment possible with the shortest possible recovery time and minimal side effects.
-
Physicist Sense Jan van der Molen plays ‘Dutch shuffleboard’ with electrons
Physicist Sense Jan van der Molen researches materials that do not exist in nature. ‘It’s fascinating to see how the properties of a material change if we manage to make it super thin.’ He will give his inaugural lecture on 21 October.
-
Elena Egorova
Science
e.a.egorova@lic.leidenuniv.nl | +31 71 527 4234
-
Hooray! This extremely sensitive microscope survived its relocation
Moving an electron microscope of 2000 kg is a delicate challenge. The highly sensitive instrument needed to be moved to a new measurement hall, but even a tiny bump could damage it. After a few nerve-racking weeks of preparing the move and reinstalment, the researchers finally have a verdict: the instrument…
-
AI application in pathology reveals novel insights in endometrial cancer diagnostics
Research at the Leiden University Medical Center (LUMC) Department of Pathology shows the power of artificial intelligence (AI) applied to endometrial carcinoma microscopy images. The group of Dr. Tjalling Bosse offers novel insights that could improve diagnosis and treatment of uterine cancer. Their…
-
Participants
The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).
-
Monitoring and detection of nanomaterials in biological media.
How do nanoparticles bioaccumulate and biodistribute in organisms?
-
Colloidal LEGO with peptides
Kros
-
Research
An overview of the research at the Biologics Formulation group
-
Technologies and social agency of painted plaster in the East Mediterranean Bronze Age
This project explored the role of material culture, in casu painted plaster and its technologies, in expressing dynamic social identities and in forging complex interwoven human relationships in the context of the Middle to Late Bronze Age of the Aegean and East Mediterranean.
-
Quantum to Classical
In Quantum mechanics, particles can be in multiple positions simultaneously. Yet, when a measurement is made, the particle is found only in one place. Technology has come to a point where we may design experiments that will tell us how.
-
ZF-HEALTH - Zebrafish Regulomics for Human Health
How can zebrafish research help understanding human diseases?
-
Gas-surface reaction dynamics and surface science
The local ordering of atoms at the surface of a metallic particle determines its catalytic activity and selectivity. As energy systems of the future will be based on efficient catalytic conversion of small molecules in closed cycles, we study how structural effects of catalysts can be used to our ad…
-
Institute of Biology
Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’
-
Cardiovascular and Metabolic Therapeutics
This research group, headed by Miranda van Eck, focusses on understanding the molecular mechanisms underlying cardiovascular and metabolic diseases. Cardiovascular disease constitutes a major health issue worldwide. Although significant knowledge has been obtained on the development of atherosclerotic…
-
Towards artificial photosynthesis: resolving supramolecular packing of artificial antennae chromophores through a hybrid approach
Promotor: H.J.M. de Groot
-
Respiratory-chain enzymes
Many metalloenzymes that are key to bioenergetics are membrane enzymes, with canonical examples the complexes I, II, III and IV in the mitochondrial inner membrane. To study these enzymes in a native-like lipid membrane environment, we aim to develop novel bioelectrochemical techniques.
-
Chara
The Green algae Chara as model system for intra and inter cellular transport processes.
-
Why Leiden University?
The Physics and Quantum Matter and Optics specialisation is one of the two programmes Leiden offers in experimental physics. The programme can be tailored to individual needs and interests.
-
Why Leiden University?
The Biological- and Soft-Matter Physics Master specialisation is one of the two programmes Leiden offers in experimental Physics. The programme can to a high degree be tailored to individual needs and interests.
- About this minor
-
Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
-
What a glow in the dark squid tells us about the human gut microbiome
Lecture, Tuesday Talks: Science Insights
-
Blog post: The nose of this wormy-shaped bacterium has a surprising symmetry
For the first time ever, Leiden biologists have found that the ‘nose’ of spirochetes – worm-shaped bacteria – have a two-fold symmetry. A remarkable discovery, as the ‘nose’ of every other bacterium has been found to have a six-fold symmetry. First author Alise Muok wrote a popular blog about the findings…
-
The magic of liquid helium: this person makes ice-cold research in Leiden possible
White clouds of ice-cold gas flowing across the floor. Magical, but be careful not to freeze your fingers off. We are of course talking about liquid nitrogen and helium. You may have seen the spectacular Freezing Physics science show by the student organisation Rino. But did you know that this commodity…
-
Movements of steroid receptors inside the cell nucleus unraveled
Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.
-
European project ImageInLife has started
The Horizon 2020 project ImageInLife has started on 1 January, followed by a kick-off meeting at the coordinating University of Montpellier at the end this month. This Marie Skłodowska-Curie training network brings together European groups that work on the imaging of vertebrates and offers fourteen…
-
Winner Physics Image Award is Volkskrant Image of the Week
Vera Meester has won the annual Physics Image Award 2016, with her photo of 'smiling' colloids. The Volkskrant published the picture as Image of the Week.
-
New ONEM Microscope to combine best of two worlds
Leiden physicists have been awarded 1.5 million euros for developing a hybrid microscope that provided nanometer-resolution. 'The idea is to combine the resolution of electron microscopy with the pros of optical microscopes.'
-
Two-photon microscope captures plant cells
Leiden physicists are helping Wageningen plant researchers to study unpredictable plant embryos. For this, they are using a novel two-photon fluorescence microscope, aided by a 30 thousand euro ZonMW grant.
-
TA grant for Irene Groot
Chemist Irene Groot has been awarded a TA grant. Together with Shell, Leiden Probe Microscopy, DSM Resolve and Utrecht University, Groot will conduct research into catalysts for the production of raw materials and fuels.
-
Collaborative and effective drug development
There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…
-
LION 2021 Image Award
It's time for the 2021 Image Award
-
LION 2020 Image Award
Corona be damned, it's high time for the yearly LION Image award! Deadline in a week.