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In the master’s specialisation Molecular Genetics and Biotechnology at Leiden University students are trained by experts in the areas of molecular biology, microbiology, plant genetics, cellular imaging, animal disease models, and various –omics technologies and the corresponding bioinformatics.

Investigating neurobiological endophenotypes of Social Anxiety Disorder

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

Are traces of fire use detectable in ancient hominin genomes?

This study analyses the prehistory of a northeastern Siberian population, the Sakha, from both a molecular-genetic and a linguistic perspective.

How does invasive hybridization affect threatened native species?

Promotor: Prof.dr. G.R. de Snoo

How do genetic and environmental factors make us vulnerable to depression?

Promotor: P.M. Brakefield

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

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Description of Triple bottom line approach for risk-benefit analysis of genetically modified crops.

Sarah Giest and Annemarie Samuels, both Assistant Professors at Leiden University, researched the quality and coverage of the data being collected for policiymakers to be used, specifically pertaining to minority groups.

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

The applications of studying the early development of insects range from agriculture to material science.

In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

How sustainable are open data infrastructures? Will the data we need in the future be available and usable? This project takes COVID-19 data/infrastructures as a case to study the sustainability and dynamics of open data infrastructures.

Starting from Husserl’s somewhat controversial claim about the immortality of the constituting subjectivity, this thesis uses the limit-case of death in order to present a phenomenological exploration of the notion of subjectivity and its relationship to nature. It also offers a second-order discussion…

Combining results from bibliometric analyses, a global sample of researcher opinions and case-study interviews, a new report reveals that although the benefits of open research data are well known, in practice, confusion remains within the researcher community around when and how to share research…

Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.

Data reuse and big data: a taxonomy for personal data reuse.

By comparing individual health data with population data, doctors can provide personalized health advice and patients can learn from each other's experiences. Wessel Kraaij, professor of Applied Data Analytics shows how personal data can have predictive value.

Modern computer-aided simulation tools used by various industries produce gigabytes of data. But currently, they take days and even up to weeks of computation effort. To make the best use of all these data, the DAMIOSO project focuses on developing algorithms and tools for managing, mining, and optimizing…

The extensive use of electronic communication channels and other devices has opened new possibilities for collecting data on human behavior. This information is sometimes openly accessible, but largely part of administrative registration systems that are not open to the broader public. The data provides…

The SAPPAO project aims to optimise the accuracy and reliability of predicting scheduled flight times. The full name of the project is 'A Systems Approach towards Data Mining and Prediction in Airlines Operations'.

What is the population size/structure and distribution of tiger and leopard inside the Bardia National Park (BNP) compared with the population outside? What is the movement and home range and conflict pattern in time and space of tigers and leopards inside the BNP compared with outside? What constitutes…

Data Sets Department of Economics

The Data-Driven Drug Discovery Network (D4N) is an initiative by researchers from Leiden University and collaborators to join efforts in applying and developing novel techniques from data science to drug discovery and related topics from bioinformatics.

The change from a closed institution to an open living environment for patients with late stages of dementia will give the patients more freedom in their day-to-day life. The effect of this change on the patients’ mobility, activity and interaction with others will be assessed with sensor technology…

Today, everybody and everything produces data. People produce large amounts of data in social networks and in commercial transactions. Medical, corporate, and government databases continue to grow. Sensors continue to get cheaper and are increasingly connected, creating an Internet of Things, and generating…

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Netherlands Statistics (CBS), Leiden University and the University of Amsterdam have started a collaboration in the form of a research project titled 'Enriching official economic statistics using data-driven modelling techniques'.

The ability to collect and interpret huge quantities of data has become indispensable to society and academia. Leiden University is a knowledge and expertise centre for data science that places the emphasis on interdisciplinary collaboration and innovation.

The majority of scientists, from archaeologists through to zoologists, collect huge volumes of data. Their massive databases contain large amounts of information which is difficult for humans to filter. With a solid grounding in statistics, we can develop algorithms for analysing and identifying patterns…

The majority of scientists, from archaeologists through to zoologists, collect enormous volumes of data. Their massive databases contain large amounts of information which is difficult for humans to filter. With a solid grounding in statistics and computer science, we can develop algorithms for analyzing…

LACDR adheres to strict data management rules, with the aim to make our data findable, accessible, interoperable and re-usable. For this reason all LACDR PhD candidates are required to prepare a data management plan and to implement data management rules accordingly. All PhD candidates follow a data…

What consequences does Brexit have for the protection of personal data?