In Dutch magazine De Psycholoog, Anne-Laura van Harmelen talks about the impact traumatic experiences, especially for those who are growing up.

Everyone has been watching the attack on Ukraine, a war on the European continent, with a sense of foreboding. It will bring devastation, loss, suffering and worry and it raises questions. With these words, Rector Magnificus Hester Bijl opened the meeting on the war in Ukraine at Wijnhaven on Thursday…

A team of five PhD students from Leiden University is in the running for first prize in the Pharmacometrics Skills Competition. In a drug development simulation, they apply their mathematical pharmacological skills to solve clinical problems. On 24 March they will compete in the finals in Orlando, F…

Lecture

Two open letters are currently circulating among civil servants in the Netherlands calling for the Dutch government to take a different stance towards Israel. Wim Voermans, Professor of Constitutional and Administrative Law in Leiden, says in a national radio broadcast that this is an unusual and unique…

Professor of Clinical Pharmacology Adam Cohen from Leiden University received the prestigious Dr. Saal van Zwanenberg Honorary Prize on 12 November. The prize honours a scientist who has distinguished themselves in the field of research that has directly or indirectly led to the development of new medicines…

Four university medical centres, including the LUMC, are joining forces to increase pandemic preparedness in the Netherlands.

This project compares and explains dynamics of cross-border cooperation among European actors in the field of counterterrorism (CT).

This study by artist Jonas Staal explores the development of propaganda art from the 20th to the 21st century.

The land question had a crucial formative influence on Mayo politics in the decades before the First World War and this book shows the part played by many prominent nationalist figures such as Davitt, O’Brien, Dillon and MacBride in shaping the political landscape in Mayo.

From the rise and fall of Egypt’s Muslim Brotherhood, to Islamic State’s attempts to create its own currency, to the dramatic return of the Taliban in Afghanistan, this edited volume from two leading scholars of contemporary terrorism assembles an enviable array of international experts to explore these…

This PhD project analyses the politics and aesthetics of depictions of torture in American and European ‘war on terror’ films.

The Central Asia Initiative in Leiden was launched by the Leiden research area Asia Modernities and Traditions (AMT) in February 2015.

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…

Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?

As a PhD candidate, you are expected to follow certain courses and training programmes in the context of your training as a researcher. The courses and training programmes will help you conduct your research, write your dissertation, develop your career, and gain self-insight. The LACDR PhD training…

Not taking into account the saturation of drug targets can lead to wrong conclusions about the duration of a drug's action. This is what former PhD candidate Wilbert de Witte writes together with the Leiden professors of pharmacology Meindert Danhof, Piet van der Graaf, and Liesbeth de Lange in Nature…

In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.

RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.

In the fall of 2021, Cleveringa professor Roméo Dallaire and world experts shared their thoughts about PTSD, children’s rights, war crimes, humanitarian law, and peacekeeping in a series of conversations about leadership and moral dilemma during times of conflict and crisis.

On 18 June 2019, Peter Kempees defended his thesis 'Hard power and the European Convention on Human Rights'. The doctoral research was supervised by Prof. R.A. Lawson and Prof. H. Duffy.

The Intelligence and Security Research Group at Leiden University explores how intelligence and security services function within political, bureaucratic, and societal contexts, and how their methods can be enhanced.

A measured yet theoretically innovative exploration of how Islamophobia and radicalisation intersect and reinforce each other.

On 22 June, Najib Amin defended the thesis 'State-building, lawmaking, and criminal justice in Afghanistan: a case study of the prison system’s legal mandate, and the rehabilitation programmes in Pul-e-charkhi prison'. The doctoral research was supervised by Jan Michiel Otto and Pauline Schuyt.

Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

Recently, the so-called refugee crisis has been framed as a threat for well-developed welfare states in Europe by the president of the Eurogroup, Jeroen Dijsselbloem. According to him, external borders have to be guarded, because otherwise ‘loads of people will come to demand support and they blow up…

Ukrainian Yana Rudenko lived through the Russian occupation of Bucha in March 2022 and thereafter came to Leiden to study. thereafter De Oekraïense Yana Rudenko (24) jaar heeft in maart 2022 de Russische bezetting van Boetsja meegemaakt en is daarna gaan studeren in Leiden.

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

Knowledge on how to adjust a drug dose in special patient populations such as (prematurely born) neonates or children, obese individuals or critically-ill patients, is not only crucial for novel compounds, but also for existing drugs which are often used in an off-label manner in these special patient…

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

Promotor: A. Kros

Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.

Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…

The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Drug Discovery & Safety and Systems Biomedicine and Pharmacology, and the Metabolomics and Analytics Centre.

Research lines within the Pharmacy group:

Lecture

Adverse drug reactions (ADRs) remain one of the major reasons for patient mortality and (early) drug withdrawal. Currently, different in vivo and in vitro models are used to assess the toxic potential of drugs in the pre-clinical phase. Unfortunately, the predictive value of this model does not fit…

Is there a sufficiently large market for drug screening and testing in Zebrafish larvae using membrane fusion?

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

How do macrophages and neutrophils contribute to metastatic onset?

At Leiden University, in both our biomedical and biological research, we use laboratory animals. Learn more about these specific areas of research and the goals we aim to achieve through these studies.

Our research programme collaborates with all kinds of partners to achieve our goal: bringing scientific discoveries to the clinic as soon as possible.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Fascinated by science since high school, Alireza Mashaghi Tabari is driven to explore new ways of thinking in medicine. With a strong academic network, he educates students and gives public lectures. For his research at LACDR, he won the C.J. Kok Public Award 2018, making him the Faculty of Science's…