Heart failure is a major health care problem with high mortality.

The ethics of ghosts, spectres, and mediums in postcolonial literature

Because of their large surface area and immunological competence, mucosal tissues are attractive administration and target sites for vaccination.

How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?

Does Artifical Light at Night (ALAN) disrupt seasonal physiological and behavioral patterns in migrating freshwater fish?

In the CarbonCap project, consumption oriented technological options and policy measures are identified as an addition to the present EU and world climate policy.

As part of the process of safeguarding the quality of our research, our institutes are audited regularly by a committee of external experts.

New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.

The abundance of images in our everyday lives-and the speed at which they are consumed-seems to have left us unable to critique them. To rectify this situation, artists such as Daniel Richter, Jaune Quick-to-See Smith, and Artur Zmijewski have demonstrated that painting is brilliantly equipped to produce…

This dissertation reports on the pedagogical content knowledge (PCK) of science teachers during a professional development program. This research intended to help us understand why and how teachers make their classroom decisions as they teach science.

On 16 November 2022 ms. Eftychia Mylona successfully defended a doctoral thesis and graduated.

This article researches the public perception of terrorist attacks by measuring the importance the public assigns to attributes of terrorist attacks.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Research on the process of artisanal and small-scale mining (ASM) in West-Africa

Members of LUXs teach courses in statistics and data science at Leiden University, Leiden University Medical Center and Leiden University College, for students of many backgrounds. They cooperate in offering wide-ranging master programs in Statistical Science and Data Science, and provide many opportunities…

Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)

This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

Together@FGGA – Together towards a safe, inclusive and balanced work environment

Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

On the 24th of June, Martijn Wackers successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Martijn on this achievement!

Promotor: Prof.dr. J.N. Kok, Co-promotor: Dr. A.J. Knobbe

Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Within this project, PeptoMiktoStars were realized through an orthogonal protecting group strategy and should be investigated further regarding their potential as drug delivery systems in the field of drug delivery to inflamed areas in cancer, bacterial infections or autoimmune diseases.

The overall aim of CAM-PaC is to contribute to solving the socioeconomic and health challenges of PDAC by an integrative and systematic functional analysis of pancreatic cancer candidate genes. CAM-PaC will develop novel cellular and animal models, as well as novel strategies to analyse and integrate…

Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh

Promotores: J. Jonkers, K.E. de Visser

The production, use, and exchange of bodily ornaments through the lenses of the microscope

The objective of the PhD Education and Supervision program is to educate PhD candidates in becoming professionals who are competent to conduct scientific research in the field of the pharmaceutical sciences independently.

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

This article describes the creation of an app that can help raise climate awareness and the action globally.

Promotor: I. A. G. Snellen, Co-promotor: M. A. Kenworthy

The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).

Complex systems can be characterized as systems in which multiple components interact with each other, often in non-linear ways. The main goal of this research will be to investigate if and how the international tax system can be defined and modelled as a complex system. Approaching the international…

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

School of pharmaceutical sciences, University of Geneva - Switzerland

Assessment of teaching is currently becoming more and more common practice. As such assessment is generally based on complex, qualitative data from multiple sources (e.g., lesson plans, video-taped lessons, written reflections of the teacher on his or her performance), the overall quality of the assessment…

This Think20 (T20) policy brief recommends the introduction of a

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Both Europe and Latin America face challenges globally and at home. Conflicts over land and resources have been resurgent in recent years.

This book is a much-needed update on our understanding of public diplomacy. It intends to stimulate new thinking on what is one of the most remarkable recent developments in diplomatic practice that has challenged practitioners as much as scholars.

The Rise and Decline of an Iberian Bourgeoisie is one of the first long-term studies in English of an Iberian town during the late medieval crisis. Focusing on the Catalonian city of Manresa, Jeff Fynn-Paul expertly integrates Iberian historiography with European narratives to place the city's social,…

Public organizations have been confronted with severe budget cuts as a result of the most recent crisis. Public managers are tasked with the implementation of cutbacks. Using different case studies within Dutch ministries and the prison sector, we assess public managers’ change leadership in times of…

This research proposal focuses on the investigation of the poetic potentials of negativity through the exploitation of failure in sound based artistic practices - a context that has not been extensively addressed.

Surveying Indigenous Peoples’ culinary practices prior to the advent of European invasions in the Greater Caribbean