1,461 search results for “single proto director” in the Public website
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Identification and characterization of viral Xrn1-resistant RNAs
Several single-stranded RNA viruses make use of Xrn1-resistant RNAs in their 3’ untranslated regions of their genome RNAs in order to increase their pathogenicity.
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Intersections: Yearbook for Early Modern Studies
This series of publications brings together new material on wellconsidered themes within the wide area of Early Modern Studies.
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A different perspective on the Carolingian economy
Material culture and the role of rural communities in exchange systems of the eighth and ninth centuries
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Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotor: Prof.dr.ir. T.H. Oosterkamp, N. de Jonge
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Bulldozed and Betrayed: Louisiana and the Stolen Elections of 1876
Prior to the 2020 presidential election, historians considered the disputed 1876 contest—which pitted Republican Rutherford B. Hayes against Democrat Samuel J. Tilden—the most controversial in American history.
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Shaping Massive Galaxies: the structural evolution of galaxies across
Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.
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Neonicotinoids in nature: The effects on aquatic invertebrates and their role in ecosystems
This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.
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Genetic diversity in the lion (Panthera leo (Linnaeus 1758)): unravelling the past and prospects for the future
Promotor: Prof.dr. G.R. de Snoo
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Mechanical Response of Foams: Elasticity, Plasticity, and Rearrangements
Promotor: M.L. van Hecke
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Supercritical carbon dioxide spray drying for the production of stable dried protein formulations
Promotor: W. Jiskoot, Co-promotor: H.A. Every
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Anisotropy, multivalency and flexibility-induced effects in colloidal systems
We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.
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PhD research at two universities
In some cases, PhD candidates are permitted to follow a PhD track that involves conducting research and receiving supervision at two institutions: Leiden University and another university. There are two arrangements of joint supervision.
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Possessives in Tongugbe, a dialect of Ewe
On February 28th, Promise Dodzi Kpoglu succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Dodzi on this great result.
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Dormancy in stochastic interacting systems
Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.
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The origins of friction and the growth of graphene, investigated at the atomic scale
Promotor: J.W.M. Frenken
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Disorder and interactions in high-temperature superconductors
This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.
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The power of one qubit in quantum simulation algorithms
Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…
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Electrocatalysis for sustainable energy
Marc Koper’s research focuses on electrocatalysis and electrochemical surface science for sustainable energy and chemistry. Reactions of interest are the redox reactions of the oxygen/hydrogen cycle (water oxidation, hydrogen evolution), the carbon cycle (reduction of carbon dioxide, oxidation of small…
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Engagement of citizens and public professionals in the co-production of public services
The idea of citizens and public professionals collaborating to provide public services has widely spread in several countries around the globe. Co-production is often presented as the go-to solution for challenges like a legitimacy crisis of both the government and the market, and financial concerns.…
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Scattering and absorption in 2D optics
Scattering of light in the presence of nano-structured materials, i.e. with features in the order of the wavelength of the light or smaller, reveals details of how light interacts with matter at the nanoscale.
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Stacked Domain Learning for multi-domain data: a new ensemble method
The aim of this project is to develop accurate but interpretable ensemble learning methods for high-dimensional multi-domain data.
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Digital tools for sign language research: towards recognition and comparison of lexical signs
On the 9th of April, Manolis Fragkiadakis successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Manolis on this achievement!
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Massively collaborative machine learning
Promotor: J. N. Kok, Co-promotor: A. J. Knobbe
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The Company Fortress. Military Engineering and the Dutch East India Company in South Asia, 1638-1795
The remains of Dutch East India Company forts are scattered throughout littoral Asia and Africa. But how important were the specific characteristics of European bastion-trace fortifications to early modern European expansion?
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The mechanism of Agrobacterium-mediated transformation of eukaryotic cells
We aim to unravel the molecular mechanisms involved in the transformation of eukaryotic cells by Agrobacterium.
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Being Muslim in Indonesia: Religiosity, Politics and Cultural Diversity in Bima
Muhammad Adlin Sila examines the range of ways Bima Muslims constitute their Islamic identities and agencies through rituals and festivals. In response to their surroundings, what it means to be a Muslim is constantly being negotiated.
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Pharmacogenomics in drug development: implementation and application of PKPD model based approaches
Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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Antiquity: Greeks and Romans in Context
This new handbook by Frits Naerebout and Henk Singor places the history of the Greeks and Romans within the larger context of the contemporary Eurasian world.
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Amphiphilic miktoarm star copolymers
Within this project, PeptoMiktoStars were realized through an orthogonal protecting group strategy and should be investigated further regarding their potential as drug delivery systems in the field of drug delivery to inflamed areas in cancer, bacterial infections or autoimmune diseases.
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Visual Relation extraction Based on Deep Cross-media Transfer Network
Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager
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Discovery and development of inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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The Interpretation of Plurilingual Tax Treaties
On 10 October 2018, Richard Resch defended his doctoral thesis 'The Interpretation of Plurilingual Tax Treaties'. The doctoral research was supervised by Prof. mr. C. van Raad.
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Individual teacher learning in a context of collaboration in teams
In this study we aimed to examine teacher learning within a context of collaboration in interdisciplinary teams.
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Utrechtse Heuvelrug
In 2020 the Utrechtse Heuvelrug project started and in a record time the entire ice pushed ridged was investigated. Thousands of potential new burial mounds, Celtic fields and cart tracks have been discovered.
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Noradrenergic control of human cognition
What is the role of the noradrenergic system in human cognition?
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Small scale kinematics of massive star-forming cores
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde
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European Markets, Trade and Digitization
Research on this theme concerns Europe’s position in global markets, its response to the emergence of new international trade and financial actors that challenge institutions where Europe has long had considerable influence.
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Bioactivity based quality control for Chinese herbal medicine
Can we establish a new quality control system for herbal medicines that is based on bioactivity rather than a few abundant chemicals?
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Internet Fragmentation: What’s at Stake?
This article tries to examine if one can take the 'One Net' for granted, since the world becomes increasingly fragmented with social and geopolitical tensions. Furthermore, the author seeks to discover what is at stake if the global interoperable network is under a threat of fragmentation.
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Critical edition and annotated translation of the Niśvāsamukha
This project will lead to a critical edition and annotated translation of the Niśvāsamukha, the opening book of the Niśvāsatattvasaṃhitā.
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Services on Environmental Statistics and Accounts
What is the best way to combine the environmental and economic data and how can we create an operational system to do so, thereby supporting the delivery of data to the Data centres on Products and Resources?
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Suppressing a Sea of Starlight: Enabling technology for the direct imaging of exoplanets
Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik
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Leiden Advocacy Project on Plastic
The Leiden Advocacy Project on Plastic (LAPP) is a pro bono initiative concerning legal questions on plastics and is founded to address and research the legal issues related to plastic pollution.
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Managing informal interaction. Stancetaking and alignment in Dutch and Indonesian
On December 13th, Maaike van Naerssen succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Maaike on this great result.
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Chemical Similarity: Structuring Risk and Hazard Assessment
At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.
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Cultural Memory of War and Conflict
From Apartheid in South-Africa to 9/11 in the United States: there is not a single culture that is not shaped by the memory of war or conflict. The minor Cultural Memory of War and Conflict focuses on how such memory cultures influence and shape societies today.
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Frontiers of Modern Physics
This is the physics summer school of Leiden University. It is part of the Leiden Institute of Physics (LION). The summer school is intended for Bachelor (BSc) students in physics. It covers topics from quantum matter and optics, to biological & soft matter physics and cosmology and theoretical physics.…