The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

Develop a prototype combined chemical-microbial enzymatical process for the sustainable, green recycling and revalorization of polyamides and polystyrene

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

Engineering an efficient microbial enzymatic polyethylene degradation pathway via an innovative combination of biochemistry and computational biology tools for enzyme discovery and characterization.

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

A neurobiological perspective on individual differences in social competence

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

Desafios para a proteção dos conhecimentos tradicionais, dos recursos genéticos e das expressões culturais tradicionais dos povos indígenas no cenário internacional

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Astronomers at Leiden University have discovered the first planets using a new instrument: the planet hunter MASCARA. This instrument, developed at Leiden Observatory, looks specifically for planet transitions around the brightest stars in the sky, which surprisingly enough have so far have hardly been…

The universities of Delft, Leiden and Rotterdam are working together to show their students what artificial intelligence (AI) means for their own field. Three AI minors will start in the 2022 – 2023 academic year and will answer questions such as: ‘How best can you use AI in your research discipline?’…

How to strike a balance between the sometimes conflicting stakes of individual, public and private data-producers and data-processors?

Evolutionary and ecological interactions affect species on genetic and phenotypic levels. This theme aims to understand these processes at multiple levels: from molecules to genomes to populations and to communities. Our research focuses on evolutionary responses to anthropogenic change, the role of…

Neuroimaging research has greatly advanced our insights on how the brain is organized. Now is the time for the next step: Imagine what would be possible when we cannot only map brain-functioning, but use neuroimaging to voluntarily regulate brain-activity!

An endless stream of publications, data and software accessible to all? Professor of Science Studies Thed van Leeuwen calls for a more human-centred approach and an overhaul of the PhD system.

Lecture

Do you still use the uMail address from your alumnus account? Then it is important to know that this mailbox will be discontinued. This is because just a handful of alumni use the uMail addresses and associated mailboxes that we currently maintain for thousands of alumni.

The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

We investigate the processes underlying the patterns. We aim to explain biodiversity by investigating the distribution, function, development, and evolution of body forms, as well as physiological and behavioural variety among species. We collaborate with those specialized in describing, archiving,…

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

This study explores the role of linguistic data in the reconstruction of Dolgan (pre)history by analyzing contact-induced changes and using them to infer information about the nature of the contact settings in which they occurred.

Antibiotics are a class of medicine most people take for granted. But pathogenic bacteria are becoming more and more resistant to our antibiotics, and this poses a great challenge for future treatments. There is thus a great societal need to identify new molecules that can address new targets and be…

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

Delineating psychophysiological endophenotypes of social anxiety disorder

Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.

Can furan-based resisn be degraded by microbial enzymes in combination with mild pre-treatment?

PhD defence

Lecture, Comparative Indo-European Linguistics (CIEL) Seminars

In this work, we attempt to answer the question:

The CMCB comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC) and the Leiden University Medical Center (LUMC).

Lecture

In this thesis,

PhD defence

Promotor: Prof.dr. C.A.M.J.J. van den Hondel, Dr. ir. V. Meyer, Co-promotor: Dr. A.F.J. Ram

Cancer represents a formidable current and future global health challenge. The LUMC medical research profile Cancer Pathogenesis and Therapy charges this challenge by developing and implementing innovative patient-tailored, multimodal diagnostic methods and treatment modalities.

How can ‘Big Data’ be used in development and humanitarian aid, and what are the risks? Leiden University and the United Nation’s Global Pulse are organising an international expert meeting in The Hague on 23 October.

The NET-ROL project builds on the EU's definition of the rule of law to investigate the role of networks in law-making, executive decision-making, and the judiciary. It examines how these networks influence the weakening of the rule of law. Through an interdisciplinary perspective, the project explores…

The new inter-university centre set up by Leiden University, Delft University of Technology and Erasmus University Rotterdam is to apply ‘big data’ research for urban issues.