1,212 search results for “effective date development” in the Public website
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Development of homogeneous catalysts for the selective conversion of levulinic acid to caprolactam
Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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PKPD and disease modelling in therapy development for amyotrophic lateral sclerosis (ALS)
We aim to gain a better understanding of the natural disease progression of ALS in order to improve clinical trial design and analysis and to support drug discovery and clinical development of new drugs.
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induction programs on beginning teachers'well-being and professional development
This thesis reports on the influence of induction programs on beginning teachers’ well-being and professional development, and the essential characteristics of an induction program. These topics were explored by means of an interview study and large scale survey study.
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Environmental assessment and guidance for the future offshore wind energy development
This thesis aims to address offshore wind energy (OWE)-related environmental impacts.
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Reparations for International Crimes and the development of a Civil Dimension of International Criminal Justice
Miriam Cohen defended her PhD dissertation entitled “Reparations for International Crimes and the development of a Civil Dimension of International Criminal Justice” on 28 June 2017. She wrote her thesis under the supervision of Professor L.J. van den Herik and Professor C. Stahn.
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'Art therapy effective in treating anxiety in women'
On 22 January, Annemarie Madani-Abbing will defend her dissertation 'Art therapy and anxiety' regarding her research into the effectiveness of anthroposophic art therapy in treating anxiety in women. We asked her about her research and what it was like to combine a job outside academia with studying…
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mRNA boosters are the most effective upon receiving Janssen vaccination
A coronavirus booster shot provides a better immune response against COVID-19 than a single vaccine dose. mRNA boosters are the most effective upon receiving Janssen. These are the results of a collaborative study between several organisations, including the Leiden University Medical Center (LUMC).…
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ZF-CANCER - Developing high-throughput bioassays for human cancers in zebrafish
How can zebrafish research help to understand and fight human cancer?
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Design and development of a comprehensive data management platform for cytomics: cytomicsDB
Promotor: J.N. Kok, Co-promotor: F.J. Verbeek
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Discovery and development of inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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AI Lab launched for effective and responsible supervision
How can you increase the effectiveness of inspectors using responsible artificial intelligence (AI)? This is the question the Innovation Center for Artificial Intelligence (ICAI) Lab AI4Oversight is tackling. By developing algorithms and methods, they try to provide optimal support for, for example,…
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Opening Minor Sustainable Development
The new CML minor Sustainable Development started on Monday 7 September 2009 with an official opening by the Vice-Rector Prof. Rietje van Dam.
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Effect of insecticides on damselflies greater than expected
The latest research from the Leiden outdoor laboratory ‘Living Lab’ shows that the insecticide thiacloprid strongly influences even the most common and robust dragonfly species in the Netherlands. The study was published in the Journal of Applied Ecology.
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Parallel developments in floral adaptations to obligate moth pollination mutualism in tribe Phyllantheae (Phyllanthaceae)
This article discusses the coevolution of several species of the tribe Phyllantheae and moths of the genus Epicephala.
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Digitizing security: How digital risk-profiling is developed in practice
How are digital risk-profiles developed and used in practice?
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Development of novel anti-cancer strategies utilizing the zebrafish xenograft model
In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…
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Bòsò Walikan Malangan: Structure and development of a Javanese reversed language
On the 24th of October, Nurenzia Yannuar successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Nurenzia on this achievement.
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Information activities
Do you want to know more about Cultural Anthropology and Development Sociology and what it is like to study in Leiden? Come to our online or on campus information events.
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The development of molecular tools for investigating NAD+ metabolism and signalling
Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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ImBod | Embodied Imamate: Mapping the Development of the Early Shiʿi Community 700-900 CE
Imami Shiʿism was a key part of the turbulent thesis and antithesis which formed Islam, and it remains greatly influential today. The aim of the ImBod project is to write the first comprehensive social history of the Imamate.
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of growth hormone secretion : application of model-informed drug development in acromegaly
Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.
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Role of near-surface environment in tuning electrochemical CO2 reduction reaction and H2 evolution reaction
This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…
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More efficient drug development with the help of computer models
The coronavirus has the world in its grip. Finding a cure has never been more important. Unfortunately, the development of new drugs for treatment of the COVID-19 disease caused by the virus and development of a vaccine are complex, lengthy, and above all costly processes. With the help of computer…
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NWO funding for just and effective energy transitions
A consortium led by Eefje Cuppen, Professor Governance of Sustainability at the Institute of Public Administration, has been granted NWO funding for a research project looking into the social, societal, and technical aspects of the energy transition.
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The Effectiveness of Dialogue in Communication, Past and Present
Research collaborative of LUCAS, LUCL and Tabula Rasa (NWO KIEM-Grant)
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Sterile neutrinos in the early Universe
Promotor: A. Achúcarro, Co-promotor: A. Boyarsky
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Novel approaches to develop filamentous micro-organisms for enzyme production (FILAZYME)
Can we develop new enzymes and cell factories to upgrade current enzyme cocktails towards complete degradation of biomass?
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Development of a universal delivery system for tailor-made cancer vaccines
The potential of liposomal cancer vaccines
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Religion, Class, and the Postwar Development of the Dutch Welfare State
Religion, Class, and the Postwar Development of the Dutch Welfare State. Dennie Oude Nijhuis.
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European foreign policy in times of crisis: a political development lens
EU foreign policy has become increasingly politicised over the past years, amongst others as a consequence of the succession of crises. Crises may engender processes of crisis framing and contestation. This article focuses on how the policy demands being voiced in these processes of contestation are…
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Profile 6. Developing a parcel based historical GIS of the Netherlands
Historical geo data are gaining in importance. Provided that they are exactly geo referenced, they can be stored into a GIS and thus be combined with all kinds of maps (topographical, pedological, etc.) and datasets. This makes it possible to analyze historical developments in space and time on a detailed…
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Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
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Ayokunu Adedokun
Faculty Governance and Global Affairs
a.b.adedokun@luc.leidenuniv.nl | +31 70 800 9503
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Jacqueline Vel
Faculteit Rechtsgeleerdheid
j.a.c.vel@law.leidenuniv.nl | +31 71 527 7260
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Carolien Rieffe
Faculteit der Sociale Wetenschappen
crieffe@fsw.leidenuniv.nl | +31 71 527 3674
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Sjoerd Lopik
Faculteit Rechtsgeleerdheid
s.j.lopik@law.leidenuniv.nl | +31 71 527 2727
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Merijn de Bakker
Science
m.a.g.de.bakker@biology.leidenuniv.nl | +31 71 527 5043
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Jonathan Phillips
Faculteit der Sociale Wetenschappen
j.p.phillips@fsw.leidenuniv.nl | +31 71 527 2727
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Stephanus Huijbregts
Faculteit der Sociale Wetenschappen
shuijbregts@fsw.leidenuniv.nl | +31 71 527 1723
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Joost Visser
Science
j.m.w.visser@liacs.leidenuniv.nl | +31 71 527 2727
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Jochanan Veerbeek
Faculteit der Sociale Wetenschappen
j.veerbeek@fsw.leidenuniv.nl | +31 71 527 3399
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Roeland Merks
Science
merksrmh@math.leidenuniv.nl | +31 71 527 7106
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Horst Fischer
Faculteit Rechtsgeleerdheid
h.fischer@law.leidenuniv.nl | +31 71 527 2727
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Paul van den Broek
Faculteit der Sociale Wetenschappen
broekpwvanden@fsw.leidenuniv.nl | +31 71 527 2727
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Xiaoyang Zhong
Science
x.zhong@cml.leidenuniv.nl | +31 71 527 5148
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Jan Michiel Otto
Faculteit Rechtsgeleerdheid
j.m.otto@law.leidenuniv.nl | +31 71 527 7260