2,483 search results for “center drug discovery initiative” in the Public website
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Discovery of a unique silver bowl from the Early Middle Ages
On an excavation site in Oegstgeest Leiden University archaeologists discovered a very rare silver bowl from the first half of the seventh century. The bowl is decorated with gold-plated representations of animals and plants and inlaid with semi-precious stones. The discovery suggests the existence…
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Lorentz Center kicks off lustrum with TEDx talk
The Lorentz Center is 25 years old. A good reason for them to contribute to a series of TEDx lectures for Leiden City of Science. Arjen Doelman, director of the Lorentz Center, was the first to enter the virtual stage.
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25 September, 2015: Opening Central and East European Studies Center
Friday 25 September, 2015 marks the official launch of Leiden University's Central and East European Studies (CEES) Center.
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NEW!! Bonn Center for Dependency and Slavery Studies
The University of Bonn, Germany, is happy to announce the opening of the Bonn Center for Dependency and Slavery Studies (BCDSS).
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LUMC involved in development of novel drugs to treat and prevent SARS-CoV-2 and other coronaviruses
The Department of Medical Microbiology at Leiden University Medical Center (LUMC) is researching antiviral drugs that could treat and prevent SARS-CoV-2 in various projects. One part of the PanCoroNed project is being led by Martijn van Hemert and involves lab tests into the antiviral effect of molecules…
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CCLS Past Events
On this page you can find information about previous CCLS events.
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Lorentz Center brings together researchers from all disciplines
For nearly twenty years the Lorentz Center has been a unique venue where researchers from all over the world work in intense collaboration. In an inspiring academic climate, researchers are free to organise specialised workshops within and across disciplines, be it humanities, social sciences or sci…
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About the programme
The two-years MSc programme spans the entire spectrum of Analytical BioSciences, Biopharmaceutics, Drug Delivery Technology, Medicinal Chemistry, Pharmacology and Toxicology.
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Archive
On this page, you will find the recordings of the online This Week's Discoveries from May 12, 2020, as well as a list of speakers since October 2015.
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Does Trump have the authority to single-handedly take on Mexican drug cartels?
The American president Trump is considering military intervention in Mexico to get rid of the drug cartels once and for all, but Mexico is not interested in other countries' interventions. According to Jelle van Buuren, Assistant Professor at the Institute of Security and Global Affairs, Trump's much…
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Sport Data Center appointed as Certified Partner of Sportinnovator
The Sport Data Center, a consortium of universities of which Leiden University is leader, is recognised as a Certified Partner of Sportinnovator. This makes the Sport Data Center an important part of the Sportinnovator ecosystem. Sportinnovator is the national programme for sports innovation, initiated…
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Anti-microbial and Anti-biofilm compounds From Indonesian Medicinal Plants
Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert
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Microscale Analytical Tools
Enabling volume-restricted metabolomics using next-generation microscale analytical tools.
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Extra curricular
Are you interested in taking up an extra challenge during your master’s programme? Have you thought about applying for our Summer School programme or are you interested in developing your personal leadership style?
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Ovalbumin coated pH-sensitive microneedle arrays effectively induce ovalbumin-specific antibody and T-cell responses in mice
The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…
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Leiden University supports the Caribbean Center for Children’s Rights
Prof. Ton Liefaard and Chrisje Sandelowsky-Bosman visited Curaçao to launch de Caribbean Center for Children’s Rights and present research.
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Flurry of new discoveries as incredible new image revealing 4.4 million galaxies is made public
Over a seven year period an international team of scientists has mapped more than a quarter of the northern sky using the Low Frequency Array (LOFAR), a pan-European radio telescope. From Leiden, Astronomer Timothy Shimwell and Huub Röttgering, among others, are involved. It reveals an astonishingly…
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Initiative for Open Abstracts launched
CWTS is proud to be one of the founding organisations of the Initiative for Open Abstracts. This initiative calls on scholarly publishers to make their abstracts available in an open infrastructure, and specifically to deposit them with Crossref.
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Receptor Residence Time
Research question
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Career prospects
With an MSc degree in BPS and Science Communication & Society you are well prepared for a broad array of career prospects in research or industry. The master’s degree is an excellent preparation for a career at the interface of science and public affairs.
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Design and application of dextran based cross-linked networks
This thesis describes the design, characterization and application of dextran based crosslinked network.
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Wil Roebroeks interviewed about new discoveries Borneo: "This killed Eurocentric views on early rock art"
In a remote cave on the Indonesian island of Borneo, a series of rock art paintings have been discovered. The oldest painting might be the oldest-known example of figurative cave art. Wil Roebroeks, not himself involved in this project, reflects on the findings in several media.
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Inverse Agonism and Constitutive Activity
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Dental remains shed light on drug use in 19th century Dutch village
Archaeologist Bjørn Peare Barthold suspected farmers in a doctorless 19th century Dutch village may have been self-medicating to manage pain and disease. By examining the skeletons' dental calculus this hypothesis could be tested. Science Magazine interviewed him about this new technique.
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Ruthenium-peptide conjugates for targeted phototherapy
As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.
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Light-activatable metallodrugs and metal-functionalized liposomes
Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…
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Leiden Healthy Society Center: making Leiden the healthiest city in the Netherlands
How can the people of Leiden age as well as possible? And what is needed to reduce health disparities? That is the mission of Leiden Healthy Society Center, a new partnership between the Municipality of Leiden, Leiden University and many other partners in the city.
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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GLOBTAXGOV team meets Inter-American Center of Tax Administrations
On 15 March 2023, the GLOBTAXGOV team at Leiden Law School met with the Inter-American Center of Tax Administrations (CIAT) to explore opportunities for cooperation, to discuss the needs of tax administrations in the field of international taxation and evaluate ongoing projects and new initiatives where…
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Champion in headwind and predictions
It is a stormy Sunday afternoon, with gusts of a whopping 110 kilometres per hour. Chemist Teun Sweere defies the enormous headwind on his city bike and wins the NK Headwind cycling after 22,5 minutes. A new highlight follows six months later: his PhD defence (14 June).
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COVID-19 Research and Education at Leiden Academic Centre for Drug Research
Since the start of the Corona crisis, several COVID-19 related research and teaching projects were started at LACDR. The computational and teaching activities started right away, as well as a large-scale metabolomics screening program by Thomas Hankemeier’s group. Other experimental activities are still…
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Kiem initiative culminates in plan to apply for larger grant
The interdisciplinary Kiem project ‘Violence as a Population Health Problem’ has resulted in a plan to apply for a large, yet-to-be-decided research grant. The so-called pressure cooker session at the heart of the project proved very effective.
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Drugs for our immune system in the right place at the right time
Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.
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Seeking new concepts to treat diseases
Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’
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Discovery of unknown translation of René Descartes’ 'L’homme' in Leiden Bibliotheca Thysiana
From time to time, manuscripts that have remained hidden for centuries turn up in library collections and archives. In the archives of the 17th-century Bibliotheca Thysiana at the Rapenburg in Leiden, kept in the Leiden University Library, Rotterdam researcher Erik-Jan Bos discovered a hitherto unknown…
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Luuk Esser in the media on discovery of 39 bodies in England
The British police discovered 39 bodies in the back of a lorry earlier this month. The refrigeration unit in which the bodies were found had entered the United Kingdom via Belgium.
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Ukraine
This is an Erasmus+ International Credit Mobility project of the Faculty of Sciences with one partner in Ukraine.
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Systems dermatology of inflammatory diseases
Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…
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A large-scale crop protection bioassay data set
ChEMBL is a large-scale drug discovery database containing bioactivity information primarily extracted from scientific literature.
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: Prof.dr. T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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Predicting early Alzheimer's disease stage in human
A new research line is the development of liquid biopsy fingerprints to predict early Alzheimer’s disease (AD) stage in human in readily accessible body fluids in human (in collaboration with: Dr. Geert-Jan Groeneveld, CHDR; Prof. Elga de Vries, Free University Medical Center; and others).
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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SysMedPD: Systems Medicine of Mitochondrial Parkinson's Disease
The overall objective of this project is to identify novel drug candidates that are capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multimodal phenotypic characterisation of cohorts of monogenic PD…
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Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity, Nat. Commun., 2017
The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…
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Unlocking Nature’s Pharmacy from Bogland Species
Development of Natural Resource for New Medicines
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Engineering of antigen-saving dissolving microneedles for intradermal vaccine delivery
The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.
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The government’s mentality hinders citizens' initiatives
The manner and context in which the government supports citizens' initiatives are often more important than the legal framework. In practice, it only creates unnecessary division and there are no solid grounds for it. Esmée Driessen, PhD candidate at the Department of Constitutional and Administrative…
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Discovery Leiden nominated for KIJK: Best Tech-idea of 2021
Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.
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Imaging of biomaterial-associated inflammation and infection using zebrafish
Which immune mechanisms are involved in host defense against Staphylococcal infection?