815 search results for “social bacterial” in the Public website
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Respiratory-chain enzymes
Many metalloenzymes that are key to bioenergetics are membrane enzymes, with canonical examples the complexes I, II, III and IV in the mitochondrial inner membrane. To study these enzymes in a native-like lipid membrane environment, we aim to develop novel bioelectrochemical techniques.
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Shy parent, shy child?
Delineating psychophysiological endophenotypes of social anxiety disorder
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn, Co-promotor: Dr. M.J.M. Schaaf
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Institute of Biology Leiden
The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology. We are part of the Faculty of Science at Leiden University.
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In Pursuit of Next-Generation Lipopeptide Antibiotics
Can new variants of daptomycin and the polymyxins be found?
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INFLANET - Training European Experts in Inflammation: from the molecular players to animal models and the bedside
How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?
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Breaking the witches' spell: towards steering the soil microbiome for volatile-mediated control of the root parasitic weed Striga
Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.
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Screening of animal venoms for antimicrobial compounds
Can animal venoms yield novel antimicrobial peptides?
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Individualized dosing of aminoglycosides and glycopeptide antibiotics in (morbidly) obese patients (AMIGO)
Timely, adequate and optimal treatment of infectious diseases is essential for the survival of patients with bacterial infections (Surviving Sepsis campaign).
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Graduate School of Science
Are you graduating at the Faculty of Science? Or are you supervising a PhD student? At the Graduate School of Science you find support at every phase of your PhD.
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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The dynamic organization of prokaryotic genomes: DNA bridging and wrapping proteins across the tree of life
Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.
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Fast vaccine design and development based on correlates of protection (COPs) Influenza as a trendsetter
New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.
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Amphiphilic miktoarm star copolymers
Within this project, PeptoMiktoStars were realized through an orthogonal protecting group strategy and should be investigated further regarding their potential as drug delivery systems in the field of drug delivery to inflamed areas in cancer, bacterial infections or autoimmune diseases.
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Quantitative pharmacological modelling for optimizing treatment of sepsis
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…
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Structural characterization of the cell envelope of Actinobacteria under changing environments
Bacteria have the ability to alter their morphology in order to adapt to changing environments.
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The architects of crenarchaeal chromatin: A biophysical characterization of chromatin proteins from Sulfolobus solfataricus
Promotor: Prof.dr. J. Brouwer, Co-promotor: Dr. Remus Th. Dame
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Buddhism and Social Justice
From 23-25 April 2014, a conference will be held on the topic of Buddhism and Social Justice. This conference confronts the common perception of Buddhism as intrinsically a tradition of peace and justice, and explores the various ways in which historically Buddhist societies of Asia have shaped, transmitted,…
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Combatting antibiotic resistance in a clever way
When you become very good at one thing, that sometimes comes at the expense of something else. Such trade-offs also apply to bacteria. When becoming more resistant to one antibiotic, bacteria can sometimes become more sensitive to another. Linda Aulin, PhD candidate in the pharmacology group of Coen…
- Publication highlights
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Is dismissal permitted following social media post?
In an appeal case, an employee of a care organisation in Nijmegen who was shown the door because of her criticism about the coronavirus voiced on LinkedIn, has had her dismissal reviewed. The court in Arnhem ruled that the employee had crossed a line and that her employer was entitled to dismiss her…
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Genetic predisposition to social anxiety disorder measurable in the brain
It was already known that social anxiety disorder often affects more than one person in the same family. But research by PhD student Janna Marie Bas-Hoogendam has now shown that there are genetic brain characteristics that are associated with social anxiety. The PhD ceremony will take place on 14 Ja…
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Bias or reality?
Negative perceptions of ambiguous social cues, social performance and physical arousal in socially anxious youth
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The Social Resilience & Security programme is inviting proposals for seed funding for interdisciplinary research
The interdisciplinary programme Social Resilience & Security is inviting proposals for seed funding. The programme aims to combine knowledge and expertise from five different faculties to study transgressive behaviours, its dimensions, aetiology, and effects of interventions with a multidisciplinary…
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Data Carpentry for Social Sciences
OSCL members, amongst which our representative in the Archaeology faculty, were part of Data Carpentry for Social Sciences. Here's what happened.
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BAT: Breaking the Transmission of Anxiety in the Family
Parents may pass anxiety onto their offspring by exposing them to anxious behaviors in novel situations. Just as the parents’ anxious signals lead to anxiety, parents’ confident signals can ward off anxiety in the offspring. This project is seeking a new way to break anxiety transmission in the family…
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The Power of Words: State Reactions to Protest Announcements
Organizations often announce their protest activities prior to their implementation to mobilize awareness, recruit supporters, and receive media attention. We are interested in the effectiveness of protest announcements—that is, under what conditions governments make concessions to avoid having an announced…
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Piecewise deterministic Markov processes: an analytic approach
Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans
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Mycobacterial cell wall-deficiency and its role in the persistence of tuberculosis
What is the role of cell wall-deficiency in the persistence of tuberculosis?
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Chromatin organization & dynamics (Dr. Remus Dame)
Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…
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HARVEST: Plant foods in human evolution
The HARVEST project explores the dietary choices that our hominin ancestors and relatives made, by recovering information on what they consumed, and how factors like environmental variation, intrinsic biology, and development of food processing technologies could have influenced their decisions.
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Discoveries in 2023
From nanoparticles to colliding ice planets and from biological origami to new x-ray scanner techniques: this year again, our scientists have made wonderful discoveries. From the largest numbers to the smallest molecules and from the oldest galaxies up to the latest algorithms, take a look at each institute's…
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Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection
Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.
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Centre for Microbial Cell Biology
The CMCB brings together microbial cell biology expertise in Leiden. It aims at optimal resonance between the groups and maximal exploitation of the available infrastructure and to develop innovative cross-boundary technology platforms.
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Chromatin organisation & dynamics
The genomic DNA of every organism is organized and compacted in order to fit inside the cell. This is achieved by the joint action of numerous architectural proteins that aid in folding the genome. Genome folding is tightly interconnected with transcription, with genes in certain regions being silenced,…
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Helena Ursic gave interview about privacy, digital technologies and social media
Our researcher and PhD candidate Helena Ursic was interviewed with Druzina, one of the biggest weekly newspapers in Slovenia.
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Our year on social media
From a successful April Fool’s prank and alumni love stories to a fabulous float on 3 Octobe: these were the highlights of our year on our social media channels. Hope you’re following us?
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Immigration and the Conditionality of Unemployment Benefits in OECD Countries
Samir Negash, PhD candidate at Leiden University and Olaf van Vliet, Professor by special appointment Comparative Welfare State Analysis at Leiden University wrote a paper regarding the topic of immigration and the conditionality of unemployment benefits in OECD countries.
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Changing the Nature of the Beast
On the first day at a new job, you have sweaty palms, nerves race through your system, and you feel insecure. Now, a couple of months later these feelings have left. You know what to do in your new role and have become part of the organization. The process leading to this result is called organizational…
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Our year on social media
It’s been a turbulent, bizarre and extraordinary year, 2020. Coronavirus turned the lives of everyone at our University upside down. Out teaching, research and all the events that are held in a year: nothing was the same as before. That this affected all of us is clear from the highlights and many reactions…
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Role of pupil-synchronisation in trust
Here I propose to study the relationship between autonomic pupil-synchronisation and trust, at the behavioural and neural level, and examine a targeted set of possible contextual moderators.
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Seminar ‘Tailored Provisions, Social Rights Compliance?’
On the 1st of November 2017, Ingrid Leijten hosted an expert-seminar titled ‘Tailored Provisions, Social Rights Compliance?’ (‘Maatwerk als Mensenrecht?’).
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Leiden Consortium on Individual Development (L-CID)
Why are not all children equally responsive to variations in the social environment?
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LLX virtual roundtable on the Social Summit and the European Pillar of Social Rights
Organised jointly by the Europa Institute, Leiden University and the Lisbon Centre for Research in Public Law, University of Lisbon on 31 May 2021.
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The importance of friendships in reducing brain responses to stress in adolescents exposed to childhood adversity: a pre-registered systematic
Up to 50% of all children and adolescents growing up worldwide are exposed to at least one form of childhood adversity (CA), which is one of the strongest predictors for later-life psychopathology.
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Schadenfreude and the role in social relations
Leiden psychologist Wilco van Dijk and communication scientist Jaap Ouwerkerk of VU University Amsterdam published a book about the emotion Schadenfreude. The authors describe what the emotion Schadenfreude really is, when people experience the emotion, and what role it plays in social relations.
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Social support and quitter-identity may help smokers quit
Receiving positive support and seeing yourself as being a quitter may help smokers quit, say Eline Meijer and colleagues. The health psychologists published their study in Social Science & Medicine.
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Sharing knowledge about social media in Africa
Africa is online. Leiden Africa expert Mirjam de Bruijn is fascinated by the fast development of mobile telephony and social media in Africa. She maintains a website on the topic, focusing on isolated, marginalised and conflict-ridden areas in Middle Africa.