In her inaugural lecture on 11 September, Miranda van Eck, Professor of Cardiovascular and Metabolic Therapeutics, addressed her research related to developing medications to keep our blood vessels clean.

Mazatec chants and ancient Mesoamerican pictography

It is sufficiently plausible that the professor from the Faculty of Archaeology exhibited the ‘inappropriate and unacceptable behaviour’ detailed in the advice of the investigating committee. That is is unless the professor provides counter-evidence. This is the conclusion of the Subdistrict Court…

What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?

With this thesis the PhD-candidate aims to enrich the body of evidence concerning the relation between stress and health, and the mediating role of (un)conscious perseverative cognitions, which is captured in the extended perseverative cognition hypothesis.

eLaw - Center of Law and Digital technologies from Leiden Law School, and the Vascular Surgery Department at Leiden University Medical Centre in the Netherlands, join forces to explore the use of AI for diabetes and secondary prevention of diabetic foot problems and won a prize for it.

In the Leiden University Medical Centre (LUMC) we strive to improve health care and the health of people.

On January 24 Professor Annemarie Meijer and Dr Sander Wezenberg received a NWO grant for their research. The grant was awarded within the Open Competition Domaine Science-M programme and is intended for innovative research areas that can form the basis for the research themes of the future.

What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?

How do plant defense genes get activated?

Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.

An essential protein that regulates our heart beat turns out to be important for cancer cells as well. The discovery might open novel treatment strategies for fighting metastasis. Publication in Science Signaling on April 4th.

The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.

Three Psychology students will present a poster of their thesis research on Alzheimer’s and dementia at the international conference AAIC Neuroscience Next. ‘I remind myself to recognise - without fear or shame - when I don't know something.’

As a result of an increased life expectancy, more people suffer from chronic diseases and discomfort. Elderly patients may have multiple diseases simultaneously, with concomitant multiple medications.

Cardiovascular disease is the leading cause of death worldwide.

PhD defence

Dr. Jessica Kiefte-de Jong and Dr. Thijs Bosker, both Assistant Professors at LUC, have been awarded by The Leiden University Fund (LUF).

The objective of the Next Generation ImmunoDermatology project (funding NWO, program NWA-ORC) is to deep profile the immune-mediated inflammatory diseases: i) atopic dermatitis (AD), ii) cutaneous lupus erythematosus (CLE) iii) chronic spontaneous urticaria (CSU) iv) hidradenitis suppurativa (HS) v)…

How do macrophages and neutrophils contribute to metastatic onset?

This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.

What are key regulators of plant ageing that can reverse ageing in plants (rejuvenation), and how can we use this knowledge to improve crop plants?

Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.

Can chemical safety assessment be improved with zebrafish embryo-based reporter assays?

We aim to conduct as few animal experiments as possible. We are continually exploring methods to Replace, Reduce, and Refine animal experiments, commonly referred to as the three Rs. Additionally, we assess each study to ensure the implementation of the 3Rs has been maximised. The Animal Welfare Body…

The collaboration between Leiden University (Medical Center) and the Autonomous University of Barcelona forms one of the most powerful international alliances for the creation and transmission of knowledge in the field of transfusion medicine.

PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.

This summer postdoctoral researcher Mónica Varela from the Institute of Biology Leiden was awarded a Veni grant from the Dutch Research Council (NWO). Six questions about her project and hopes for the future.

PhD candidate Maia Casna was a guest on the new episode of the Wetenschappelijke Wezens podcast. In it, Maia discusses her research on urbanisation and respiratory diseases while uncovering the intricacies of studying the human past and bones.

How can we extend the drug residence time to combat diseases more effectively?

How can you use robots and automatic recognition of microscopic images to test the effect of drugs exceptionally quickly?

The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

Overkleeft

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.

The Horizon 2020 project CoSTREAM aims to improve our understanding of the co-occurrence of stroke and Alzheimer’s disease. It has long been known that both diseases share underlying causes, but their exact interaction or link is not fully understood. CoSTREAM combines multiple factors to identify and…

Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…

Lecture

The fastest chemical reaction in the universe takes place inside our eyes.

Street theatre, drama, poetry and a lot of science: Leiden's Rapenburg was the backdrop for the fifth Night of Art and Knowledge on Saturday 16 September. Many University buildings - from the Observatory to the Hortus - opened their doors to artists, scientists and a public curious to know more.

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

Christiaan van Gorkum passed away on 30 October 2015.

Biology PhD student at Leiden University Kevin Groen and his identical twin brother Marvin Groen (a biology student as well) will be on Dutch Television from Tuesday 5 September in the programme called Vroege Vogels every week (NPO 2, 19:20).

PhDArts alumnus Joost Grootens’ book 'Blind Maps and Blue Dots: The Blurring of the Producer-User Divide in the Production of Visual Information’ has been selected in the competition the Best Dutch Book Designs 2021.