1,455 search results for “health diseases” in the Public website
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Inflammafish: Cross-talk between inflammation and autophagy in tuberculosis
Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.
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Roeland Merks
Science
merksrmh@math.leidenuniv.nl | +31 71 527 7106
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Patrick van Hage
Science
p.van.hage@biology.leidenuniv.nl | +31 71 527 4950
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Maria Yazdanbakhsh
Faculteit Geneeskunde
m.yazdanbakhsh@lumc.nl | +31 71 526 5067
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Jordy van der Beek
Science
j.g.van.der.beek@cml.leidenuniv.nl | +31 71 527 2727
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Joey Zuijdervelt
Science
j.l.zuijdervelt@lacdr.leidenuniv.nl | +31 71 527 6227
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Tuomas Aivelo
Science
t.j.e.aivelo@biology.leidenuniv.nl | +31 71 527 2727
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Coen van Hasselt
Science
coen.vanhasselt@lacdr.leidenuniv.nl | +31 71 527 3266
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Stress Less Project: Effectiveness of school-based intervention programs
What is the effectiveness of two school-based skills-training programs in promoting mental health?
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Dr. Kiefte-de Jong and Dr. Bosker, Assistant Professors at LUC, both awarded LUF Awards
Dr. Jessica Kiefte-de Jong and Dr. Thijs Bosker, both Assistant Professors at LUC, have been awarded by The Leiden University Fund (LUF).
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Vidi grant for research into childhood trauma, friendship and mental health
Anne-Laura van Harmelen has received a Vidi grant from the Dutch Research Council (NWO). This talent programme will enable Van Harmelen to research the social and neurobiological mechanisms of resilience in young people with childhood trauma.
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Inkomen en afkomst zijn risicofactoren bij kans op hart- en vaatziekten
Nederlanders met lage inkomens lopen tot 1,5 keer meer risico op het krijgen van een hartaanval of beroerte dan rijkere landgenoten. Bij Surinaamse Hindoestanen is dit risico 1,9 keer hoger. Dat blijkt uit onderzoek van het LUMC en het HagaZiekenhuis. Nederlandse artsen kijken tot nu toe niet naar deze…
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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New Medical Delta professors mean boost for health and technology research
Five of the new Medical Delta professors who now hold an appointment at multiple institutions are affiliated with Leiden University/LUMC. They are psychologist Andrea Evers and four LUMC professors.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Vision and Mission
The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.
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Cell Observatory: visualising structures of life
From molecule, to cell, to organism. The high-level drug research at the Cell Observatory aimes at reducing the spread of cancer and developing new medicines for tuberculosis.
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The recognition process of youth with problematic anxiety in general practice
Do general practitioners recognize children with or at risk of problematic anxiety and is there a pattern that might help differentiate those with and without anxiety disorders in general practice?
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Macrophage activation and cholesterol accumulation in atherosclerosis development
Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck
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Mycobacterial cell wall-deficiency and its role in the persistence of tuberculosis
What is the role of cell wall-deficiency in the persistence of tuberculosis?
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New Student Wellbeing task force kicks off with mental health
Stress among students is a growing problem. A new Student Wellbeing taskforce will be looking at the mental health of students at Leiden University.
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There could be surprises at the Healthy University workshops
From exercises for working more healthily to practical tips about getting a good night's sleep. Students and staff who take part in the Healthy University Workshops on 18 or 19 October will be given tips to suit their personal situation.
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SKY HIGH: Vertical farming a revolution in plant production
As a new vision on food production, the feasibility study on LED light to grow crops with the biological- and chemical evaluation of final products.
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Marker assisted breeding for thrips resistance in tomato
Which plant leaf characteristics are involved in thrips resistance in tomato?
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Horizontal gene transfer and spreading of biosynthetic gene clusters and antimicrobial resistance
Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.
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This week the National Antibiotic Development Platform, NADP, was officially launched via a meeting in Utrecht.
Antibiotic resistance is one of the major threats to human health. This week the National Antibiotic Development Platform, NADP, was officially launched via a meeting in Utrecht, with many of the stakeholders in the field present.
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Healthy ageing? Shift the focus from the individual to the population
David van Bodegom, Professor of Vitality in an Ageing Population, will give his inaugural lecture on 11 November, also titled Vitality in an Ageing Population. According to Van Bodegom the key to healthy ageing is the lived environment. In the fight against lifestyle-related conditions, he therefore…
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Clinical applications of (pharmaco)metabolomics
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…
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ImageInLife: Training European experts in multilevel bioimaging, analysis and modelling of vertebrate development
How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?
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Sources of Meaning among organized non-religious ‘secular’ persons
Recently, studies have shown the similarities and differences in sources of meaning between religionists, ‘nones’ and atheists (see several studies of Schnell and others). The present study that will be conducted in three European countries tries to clarify the relationship between meaning giving and…
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The dual role of state capacity in opening socio-political orders: assessment of state capacity in Belarus and Ukraine
Antoaneta Dimitrova, Professor Comparative Governance at Leiden University, Honorata Mazepus, Assistant professor at Leiden University and Dimiter Toshkov, Associate Professor at Leiden University, together with three other authors researched which aspects of state capacity might contribute to opening…
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Annemarie Meijer
Science
a.h.meijer@biology.leidenuniv.nl | +31 71 527 4927
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Distance-based analysis of dynamical systems and time series by optimal transport
Promotor: S.M. Verduyn Lunel
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Chemokine signaling in Tuberculosis and Salmonella infection
Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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EPCEM 2001: Differences in the authorization process of GMOs in the EU and the USA
This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…
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Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
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Small changes for long term impact: optimization of structure kinetic properties: a case of CCR2 antagonists
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman
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Live or let die: the intracellular fate of pathogenic mycobacteria
How do mycobacteria subvert the defenses of host immune cells?
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Optimization of Patient Flow through EMT Facilities Applying Dynamic Behavioral Simulation Models
This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…
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We all BENEFIT: The Ecosystem for Healthy Living
The modification of risk factors and related health behaviors lies at the very core of adequate cardiovascular risk management, yet evidence shows that the majority of people with cardiovascular disease (CVD) fail to achieve a healthy lifestyle in the long term. The main objective of this project is…
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Targeted biomolecule production for therapeutic use
We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.
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‘Seeing voices’: the role of multimodal cues in vocal learning
Can birds - like people- ‘see’ voices and learn how to sing by listening and watching?
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The serosa: an evolutionary novelty in insect eggs
What is the function of the insect serosa?
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MeRGeR: Physiological significance of the glucocorticoid and mineralocorticoid receptor signaling in the innate immune system
Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?
- Lectures
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The quest for new medicines against tuberculosis
Can drug screening for tuberculosis treatment be made more efficient?
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Conquering the fortress: New strategies for the treatment of tuberculosis
Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?