1,817 search results for “system cell transplant” in the Public website
-
Duality, bosonic particle systems and some exactly solvable models of non-equilibrium
Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander
-
How oxygen deprivation causes cancer cells to spread
In breast cancer, metastasis rather than the primary tumour is the cause of death. A lack of oxygen in the tumour cells promotes this metastasis, accompanied by a reprogramming of the cell's metabolism. PhD candidate Qiuyu Liu investigated these alterations to get more knowledge about the actionable…
-
Cancer cell mechanism found to be used against itself
Leiden biophysicists have found a new possible way to attack cancer cells. They have located ‘sinkholes’ on the cells where receptor proteins disappear from the surface. If a drug could push these proteins towards those areas, it would kill the cancer cell.
-
New cell therapy facility at Leiden Bio Science Park
American pharmaceutical company Bristol Myers Squibb will be building a new (CAR-T) cell therapy facility in the Oegstgeest part of the Leiden Bio Science Park. The company will manufacture and develop CAR T-cell therapy for patients with blood cancer (leukaemia), for example.
-
The role and analysis of molecular systems in electrocatalysis
Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.
-
Development of novel metabolomics and systems pharmacology methods
We are developing biology-driven platforms to measure metabolites based on liquid chromatography-mass spectrometry (LC-MS), gas chromatography-MS (GC-MS), and capillary electrophoresis-MS (CE-MS).
-
Sensing drug responses of single cells using optical tweezers
Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.
-
Md Faysal Tareq
Science
m.f.tareq@cml.leidenuniv.nl | +31 71 527 2727
-
Quantitative Super-Resolution Microscopy
Promotor: T. Schmidt
-
Assistant Professor in Machine Learning for Quantum Systems
Science, Leiden Institute of Advanced Computer Science (LIACS)
-
Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
-
The Leiden Oxford Transplantation Summer School
Course
-
Can an employer demand messages from a private cell phone?
The Netherlands Council of State ruled at the end of March that WhatsApp and text messages on the work and private cell phones of civil servants are considered to be official records. This decision puts the government in a difficult position. How are you going to store millions of texts and WhatsApp…
-
FAIRDOM – FAIR Sharing for Systems and Synthetic Biology
FAIRDOM consortium is an open initiative of various partners including funding programmes, large-consortia, institutes, small groups as well as individuals.
-
LUMC to build largest stem cell facility in the Netherlands
The Leiden University Medical Center (LUMC) will start construction this year of the largest non-profit stem cell and gene therapy facility in the Netherlands, and one of the largest facilities in Europe. NECSTGEN – the Netherlands Center for the Clinical Advancement of Stem Cell and Gene Therapies…
-
Targeting macrophages in renal transplantation
PhD defence
-
Minute molecular movements might lead to more efficient biofuel cells
Leiden researchers have found minute movements in the laccase enzyme. This discovery could lead to the development of much more efficient biofuel cells. Publication in Biophysical Journal.
-
Human DNA softer than DNA single-celled life
Single-celled organisms have stiffer DNA than multicellular lifeforms like humans and rice. Theoretical physicists managed to simulate the folding in full genomes for the first time to reach this conclusion. Publication in Biophysical Journal on February 7.
-
Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
-
Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice
In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.
-
Characterization and skin permeation of ketoprofen-loaded vesicular systems
PURPOSE: To determine the effect of elasticity on the skin permeation of ketoprofen from surfactant-based vesicular formulations and elastic liposomes.
-
Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
-
Trans-kingdom DNA transfer
The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.
-
Movements of steroid receptors inside the cell nucleus unraveled
Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.
-
Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
-
How our single-celled relatives package their DNA
A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. PhD defence on 5 December.
-
Reactive Copolypept(o)ides as Novel Material for Systemic siRNA Delivery
The aim of the project is the development of polypept(o)ide-based delivery systems to use siRNA as systemic applicated therapeutic agent against e.g. solid tumors
-
Things hold together: Foundations for a systemic treatment of verbal and nominal tone in Plateau Shimakonde
This is a study of Plateau Shimakonde, a sub-dialect of the Makonde language which is spoken on the Makonde Plateau in northern Mozambique.
-
Growth and development of actinomycetes
We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.
-
Stephan Raaijmakers: 'Humans and systems have to learn to understand each other better'
You can ask virtual assistant Siri about the weather, but you can’t have a real conversation with it yet. You can’t refer to anything that’s been said before, or ask the system why it says what it says. Stephan Raaijmakers, Professor by Special Appointment from TNO, hopes to change this.
-
Systems pharmacology-based optimization of postoperative morphine treatment
Previous research has found important inter-individual differences in the pharmacokinetics (PK) of morphine in special populations such as children, the morbidly obese or the critically ill.
-
Quantum Many Body Physics in Condensed Matter and Ultracold Atomic Systems
The research in my group addresses a range of topics related to quantum many-body physics.
-
Distance-based analysis of dynamical systems and time series by optimal transport
Promotor: S.M. Verduyn Lunel
-
Building land tenure systems: the political, legal, and institutional struggles of Timor-Leste
On 24 September 2020, Bernardo Ribeiro de Almeida defended his thesis 'Building land tenure systems: the political, legal, and institutional struggles of Timor-Leste'. The doctoral research was supervised by Prof. A.W. Bedner. Co-supervisor was Dr. C.I.M. Jacobs.
-
Immunity, Infection and Tolerance
The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.
-
From molecules to planets: Exploring the chemical heritage of solar systems
Walsh
-
Fruits of our labour: Work and organisation in the global food system
This is the first special issue of any organisation studies journal on food labour. Why is this a big deal? In this Introduction, we argue that the field should pay much more attention to the agri-food system and the work that goes into producing, distributing and consuming foodstuff. Food is such an…
-
"Entrapment by Consent": the Co-ethnic Brokerage System among Ethnic Yi Labor Migrants in China
Xinrong Ma defended her thesis on 13 February 2018
-
Citizenship? Collective Food Procurement in European Cities in "Food, food systems, and agriculture"
Grasseni's contribution to this special feature on food cultures, food systems, and agriculture in Europe builds upon her ongoing project Food citizens? Collective food procurement in European cities: solidarity and diversity, skills and scale.
-
Saloni Saxena
Science
s.saxena@biology.leidenuniv.nl | +31 71 527 4950
-
SMALL Savannah : an information system for the integrated analysis of land use change in the Far North of Cameroon
Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan
-
Structural Properties of Single Server Queueing Systems: Efficient Methods via Lumping and Dynamic Programming
This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.
-
Protostellar jets and planet-forming disks: Witnessing the formation of Solar System analogues with interferometry
The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.
-
WARN-D: developing an early warning system for depression in students
My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?
-
Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
-
Antonius Johannes Rabelink
Faculteit Geneeskunde
a.j.rabelink@lumc.nl | +31 71 526 2148
-
Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
-
Ecological functioning of bacterial chitinases in soil
Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)
-
ZF-CANCER - Developing high-throughput bioassays for human cancers in zebrafish
How can zebrafish research help to understand and fight human cancer?
-
Development of a academic monitoring system for students with learning problems in secondary school
Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years