1,461 search results for “single proto director” in the Public website
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Improved Strategies for Distance Based Clustering of Objects on Subsets of Attributes in High-Dimensional Data
This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.
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Operators in the lexicon. On the negative logic of natural language
Operators in the Lexicon opens with an old chestnut: why are there no natural single word lexicalizations for negations of the propositional operator and and the predicate calculus operator all: why neither *nand nor *nall?
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Policy Effectiveness through Configurational and Mechanistic Lenses: Lessons for Concept Development
Valérie Pattyn, Assistant Professor at Leiden University, researched
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Stone Artefact Production and Exchange among the Lesser Antilles
ASLU 13
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Institutes
All research at Leiden University is organised into institutes. To do justice to the wide spectrum of research (and consequently teaching) that comes from these, you will find descriptions of all the Leiden institutes on these pages.
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Roman Political Culture. Seven Studies of the Senate and City Councils of Italy from the First to the Sixth Century AD
This volume offers an innovative analysis of Roman political culture in Italy from the first to the sixth century AD on the basis of seven case studies.
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About us
The Mathematical Institute is one of the eight institutes of the Faculty of Science. The institute operates as a single unit defined by the activities of its members.
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Poetry, rhythm, and meter
Knowledge and culture subproject 4:
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Quantum Matter and Optics
The quantum nature of matter and light has grown into a broad and fruitful research field for theorists and experimentalists alike. It combines foundational research with toward applications, the most well known of which is the quantum computer.
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The evolution of Dutch
In order to compare languages, it is important to have a thorough knowledge of the specific languages you are studying. Gijsbert Rutten and his team are investigating the origin of Standard Dutch and the repression of ‘non-standard’ variants between 1750 and 1850.
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Ahmed Mahfouz: 'The mystery of brain diseases, unravelled cell by cell'
Which brain cell does what, when Parkinson's disease arises? It won't be long before this jigsaw is solved piece by piece. Ahmed Mahfouz, computational biologist, combines bio-knowledge from Leiden with algorithms from Delft and is getting closer to finding the key.
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Towards the development of synthetic vaccines against tuberculosis
The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.
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Triple Bioorthogonal Ligation Strategy for Simultaneous Labeling of Multiple Enzymatic Activities
Three at the same time: a ligation strategy combining tetrazine–norbornene cycloaddition, Staudinger–Bertozzi ligation, and copper(I)-catalyzed click reaction was used to label the three catalytic activities of the proteasome simultaneously in a single experiment. The orthogonality of the three ligation…
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Determining the structure of a chemotaxis kinase complex with receptor mimetics and cryo-EM
Can we determine the 3D structure of a chemotaxis core complex using single-particle reconstructions via cryo-EM?
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Prior Research
The van Exter group has an extensive history of prior research in classical and quantum optics. As former part of the group of Han Woerdman, we have studied topics as diverse as:
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Admission and application
This minor is developed for third year students and is only accessible for bachelor students who have obtained their ‘propedeuse’, we are sorry to tell you HBO students cannot apply.
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Serving the East and the West – Strategies in Imperial Career Paths Within the VOC and the WIC
How did interests outside the scope of the Dutch chartered trading companies influence the career-paths of Dutch colonial governors?
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Marian Klamer receives NWO Vici-grant
Linguist Marian Klamer, associated with Leiden University Centre for Linguistics, is one of the 31 scientists to receive a NWO Vici-grant for her researchproject 'Language as a time machine'.
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Quantum dots in microcavities: From single spins to engineered quantum states of light
PhD defence
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Predicting alcohol use disorder through machine learning
How to come to valid risk stratification of alcohol use disorder?
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Searching by Learning: Exploring Artificial General Intelligence on Small Board Games by Deep Reinforcement Learning
In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…
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Scanning mutagenesis in a yeast system delineates the role of the NPxxY(x)(5,6)F motif and helix 8 of the adenosine A(2B) receptor in G protein
Source: Biochem Pharmacol, Volume 95, Issue 4, pp. 290-300 (2015)
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The excavation of the Paardenmarkt Alkmaar
In June-August 2010 large scale excavations were executed on the cemetery belonging to the monastery, an area now termed the Paardenmarkt, by Hollandia Archeologen in cooperation with Leiden University. During the course of nine weeks, the students from the former minor Human Osteoarchaeology excavated…
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Proteochemometrics
Research question
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Archaeology of the Americas
North, Middle and South America together constitute the single largest area in World Archaeology that is taught as a single focus. It is also the only major world area that saw societies develop from hunter-gatherers to early empires entirely independent from developments in Eurasia & Africa. It is,…
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Banking Regulation in and for Crisis
In this article, Lydie Cabane, Assistant Professor at the Institute of Security and Global Affairs, and Martin Lodge address the question of how to manage banking crises, a question that has gained prominence since the banking crisis of 2007-2009. This article sets out the rationale for regulating for…
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Opening a Bank Account
It is advisable to open Dutch bank account once you move to The Hague (if you do not have one already), as it will allow you to get many other services such as a mobile phone contract, transportation, etc.
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Proteins in harmony: Tuning selectivity in early drug discovery
This thesis describes the importance of being able to control the selectivity of potential drug candidates.
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Read about science & research
Scientific research is the main focus of our program. We expect new students to understand what it is and how it works.
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Dirk Bouwmeester Lab - Quantum Optics and Quantum Information
The research program of the QO group has three leading themes: Optical Physics, Quantum Optics, and Photon-Matter Interactions. We work mostly at the boundaries between these themes with entanglement as a bridging and binding agent.
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M. Wang
Chair of LU-European Center for Chinese Medicine and Natural Compounds, Institute of Biology, Leiden University - the Netherlands
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Bioorthogonal Antigens
The aim of this thesis is to explore the use of Bioorthogonal Antigens to study the cross-presentation pathway.
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On shape and elasticity: bio-sheets, curved crystals, and odd droplets
Because thin systems can deform along the thickness with relative ease, the interplay between surface mechanics and geometry plays a fundamental role in sculpting their three-dimensional shape.
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Journal Observatory – Toward integrated information about the openness of scholarly journals
Lots of efforts are being made to promote open science practices in scholarly publishing. However, information on the openness of scholarly journals is highly fragmented. There are various data sources that provide information on specific aspects of openness, but there is hardly any integration of these…
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LUGO Packaging Event
Product packaging is essential. It prolongs shelf-live and highly influences purchasing decisions. However, it’s also a big source of waste, especially single-use plastic. Have you ever felt conflicted choosing a product due to the material it’s packaged in? Or opted for a different product due to its…
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Multi-angle DLS Facility
Multi-Angle Dynamic Light Scattering (MADLS) is a technique that is used to determine properties of particles in suspension. The measurements give the hydrodynamic size distribution of individual particles as well as particle clusters, and assists in the interpretation of the stability of the particles…
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Gold nanorod photoluminescence: applications to imaging and temperature sensing
Promotor: M.A.G.J. Orrit
- Prof Dr Matthias Erb
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Our approach
Our group operates at the cross-roads of different disciplines: molecular and cellular microbiology, biochemistry, structural biology and biophysics. The group harbors expertise in a multitude of molecular and cellular approaches including:
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Wetland Farming in the area to the south of the Meuse estuary during the Iron age and Roman period
An environmental and palaeo-economic reconstruction.
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Jeroen Jansen
Assistant Professor at the Department of Analytical Chemistry, Radboud University Nijmegen, the Netherlands
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Nagtzaam & Van Erkel, ‘Preference votes without preference?’
Political scientists Marijn Nagtzaam (Leiden University) and Patrick van Erkel (University of Antwerp) investigate how electoral rules affect intra party preference voting. Focusing on the effect of two specific rules—the option to cast a list vote and on a single versus multiple preference vote—and…
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Mathematical modeling of cellular stress pathways for mechanistic understanding of chemical-induced liver injury
Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…
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Not wrapping but folding: Bacteria also organise their DNA (but they do it a bit differently)
Some bacteria, it turns out, have proteins much like ours that organise the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for Biology. The discovery helps us better understand…
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R-ELEVATION
How do plant defense genes get activated?
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Robert Smit receives his PhD with distinction. ‘I am happy to be back in the lab’
An all-optical transistor, a molecule-sized sensor and a new kind of single-photon source for quantum communication. All dreamed applications of fundamental physics that are one step closer thanks to Robert Smit. On 12 June, he defended his PhD thesis with distinction.
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Supramolecular and Biomaterials Chemistry
Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…
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Managing Diversity: Supervising Functions in Managing Colonial Workplaces
Managing Diversity: Supervising Functions in Managing Colonial Workplaces
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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Mapping Identity in Dutch Colonial Sri Lanka (1658-1796)
At the heart of this study is a thorough inquiry of categorisations of social identity used in the VOC’s record-keeping bureaucracy. How were service, occupational and caste groups classified and shaped by the VOC?