Free playtime and physical play are of great importance to children's social development. That is the main conclusion of innovative research by developmental psychologists and computer scientists from Leiden University.

Lecture

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

How can the transport of molecules in living cells help to target medicines at exactly the right place?

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

SLAVES TO THE SYSTEM: Locating Responsibility for Forced Expatriate Labour Practices by the Democratic People’s Republic of Korea (DPRK)

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

It is one of the most personal and simultaneously most universal experiences of human life: caring for a young child. Professor Sarah Cramsey has been awarded an ERC Starting Grant to investigate how factors such as nationality, political systems, and religion influence the first thousand days after…

Think tanks have proliferated in most Western democracies over the past three decades and are often considered to be increasingly important actors in public policy. Still, their precise contribution to public policy remains contested.

On 14 November 2019, Luis Fiallos Pazmino defended his thesis 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon and Prof. E.C.P.D.C. De Brabandere.

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

Using artificial intelligence is more complicated for the government than for companies. Bram Klievink, Professor of Public Administration, aims to identify the problems and find solutions.

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…

The potential of liposomal cancer vaccines

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

From descriptive to physiological models that can predict oral absorption and elimination of CYP3A substrates across the pediatric age range.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

Promotor: S.M. Verduyn Lunel, Co-promotor: S.C. Hille

The Applied Mathematics Programme consists of 120 European Credit Transfer System (EC) points. The programme consists of advanced courses (min 60 EC), a research project (40 EC) and electives (max 20 EC).

The research specialisation offers you the opportunity to spend two full years on training in applied mathematics to become an independent scientist with a strong theoretical basis.

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

Lodewijk Petram, author of the book 'The World's First Stock Exchange', discussed the rise of the Amsterdam stock exchange in the 17th century in the ninth Hazelhoff Guest Lecture.

Single-Molecule Microscopy (SMM) techniques constitute a group of powerful imaging tools that enable researchers to study the dynamic behavior of individual molecules.

What is Interaction between Legal Systems (ILS) and what does it entail as research profile area at Leiden Law School? More on this at the kick-off event of ILS 2.0. This will take place on Wednesday 26 October 15.00 – 17.00 in the Grotiuszaal (A051 KOG). The afternoon will be closed with drinks at…

A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.

Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

What is the origin of solar systems?

On 5 October, Katherine Filesia defended the thesis 'Speaking the same language: the introduction of the Anglo-American trust into the Dutch legal system'. The doctoral research was supervised by Pim Huijgen and Frans Sonneveldt.

The languages of the Mbam-et-Inoubou District of the Centre Region of Cameroon have a unique position in Bantu linguistics. Being in between

Promotor: Prof.dr. L.J. Slikkerveer

If you are interested in studying stochastics, the following information will help you to choose the right path.

This doctoral thesis comprises four studies on the content and structure of physics teachers’ belief systems about teaching and learning physics in secondary education in the Netherlands.