PhD defence

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.

The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).

Is blended care a feasible and effective treatment method for social anxiety in adolescence?

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An important hormone excreting gland in the human body is the pituitary

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Kim de Jong, Jaime Delgadillo, and Michael Barkham offer valuable insights in their book 'Routine Outcome Monitoring and Feedback in Psychological Therapies' on how therapists and trainees can use feedback to inform treatment decisions and, ultimately, enhance patient outcomes.

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

In order to optimize treatment, it is necessary to closely monitor and manage the patient’s health status by means of ‘precision diagnostics, personalized prognosis and targeted therapy’. The specialisation combines the techniques and applications of these sensing (monitoring) and stimulation techniques.…

The ability to collect and interpret huge quantities of data has become indispensable to society and academia. Leiden University is a knowledge and expertise centre for data science that places the emphasis on interdisciplinary collaboration and innovation.

On this page you will find an overview of awards and prizes granted to our staff and students in 2024, as well as special appointments at Leiden University and other institutions.

When you become very good at one thing, that sometimes comes at the expense of something else. Such trade-offs also apply to bacteria. When becoming more resistant to one antibiotic, bacteria can sometimes become more sensitive to another. Linda Aulin, PhD candidate in the pharmacology group of Coen…

Do young people who want to change gender have the unconditional right to medical treatment? Pediatric Endocrinologist Martine de Vries, who is also Professor of Medical Ethics, treats transgender children and adolescents. She will discuss this in her ‘Pride Talk’ on 18 September.

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

The curriculum of the master's specialisation School Psychology is in total 60 EC and can be completed within one year. The programme offers a variety of courses and a supervised master's thesis.

Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the renowned scientific journal Nature Cardiovascular Research. 'This discovery suggests that treatment methods for autoimmune diseases might also be effective…

Research lines within the Pharmacy group:

The chain that supplies patients with new medicines consists of various complex links: from fundamental research to clinical tests and production. This entire chain is represented in Leiden. Leiden University, the Leiden University Medical Center (LUMC), and the companies on the Leiden Bio Science Park…

Can we bring novel treatment options to the clinic for UM patients with liver metastases?

The Institute of Psychology is responsible for innovative and interdisciplinary research and education within psychology and related disciplines. It focuses primarily on four broad areas: Health and Wellbeing; Development and Learning; Socio-Cognitive-Affective Decision-making and Advanced Behavioural…

ADHD & ME aims to explore how enhancing self-esteem can break the relation between ADHD symptoms and comorbid disorders, such as anxiety and depression. In this study we assess the effectiveness of a Cognitive Behavioural Therapy (CBT) program called Competitive Memory Training (COMET) for improving…

On 5 November 2021, Professor Michiel van de Sande of the Department of Orthopedics in the Leiden University Medical Centre (LUMC) delivered his inaugural lecture ‘The Art of Doing and Doing Nothing’. Van de Sande used the opportunity to explore both physical and philosophical aspects of co-decision…

The rapid advances in imaging technology enable to see inside the body with ever increasing detail.

In what way can new tools and techniques be used to develop drug candidates for the treatment of neurological disorders?

The advanced insights obtained for the CNS PBPK model development are currently used to develop advanced mathematical models for drug distribution prediction in other body tissues protected by barriers, such as the gut. The gut PBPK model will be linked to drug effects for treatment of colon cancer.

This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.

The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.

Health research, medical practice and consequently the whole population is increasingly affected by digitization, data science and AI.

There is much unrest among local stallholders in Utrecht. Owners who for decades had a permanent pitch for their stall are no longer guaranteed this due to new European regulations. So no more benefits for the current stallholders which is causing them great uncertainty and frustration.

The Young Academy Leiden (YAL) has awarded an 444 Interdisciplinary Activity Grant to Anna van Duijvenvoorde and Stephanie Rap to organise a half-day seminar on young adults, neuroscience and the law.

Predicting cancer survival with machine learning, that is the aim of a new collaboration between the Mathematical Institute, the European Organisation for Research and Treatment of Cancer (EORTC) in Brussels and Leiden University Medical Center. The focus of this project is to characterise the model…

Leiden biophysicist Stefano Coppola has received the prestigious AXA Research Fund postdoctoral fellowship. With this grant he can work for two years on a project to research the role of mechanical factors in the development of pancreatic cancer.