1,381 search results for “animal” in the Public website
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Early Modernity Matters
This research network aims to promote cross-regional collaboration in the field of cultural history in early modern Asia at the intersections of visual, material, textual and aural culture.
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Determining the most appropriate dose metrics for evaluating dose-response relationships of metal-based nanoparticles to Zebrafish embryos
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Emblems and the Natural World
The multiple connections between emblematics and Natural History in the broader perspective of their underlying artistic, literary, political and religious ideologies.
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CAM-PaC
The overall aim of CAM-PaC is to contribute to solving the socioeconomic and health challenges of PDAC by an integrative and systematic functional analysis of pancreatic cancer candidate genes. CAM-PaC will develop novel cellular and animal models, as well as novel strategies to analyse and integrate…
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Pursuing Whiteness in the Colonies: Private Memories from the Congo Freestate and German East Africa (1884–1914)
Pursuing Whiteness in the Colonies offers a new comprehension of colonial history from below by taking remnants of individual agencies from a whiteness studies perspective. It highlights the experiences and perceptions of colonisers and how they portrayed and re-interpreted their identities in Afric…
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On the efficacy of digitized storybooks for young learners with attention problems
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Patterns of Paleomobility in the Ancient Antilles
Patterns of paleomobility in the Caribbean were studied through an inter-disciplinary approach using a combination of archaeological, osteological, mortuary, and isotopic data.
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Alexandria the Cosmopolis
A global perspective
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Human Evolution
This multidisciplinary minor provides students with knowledge on how and why humans became the way they are. The minor focuses on the evolution of the species Homo sapiens from other hominin lineages and animal ancestors, and on the various factors shaping this process. Not only is human evolution of…
- Dossiers
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Research projects
An overview of research projects at the Predictive Pharmacology group.
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Veni-grant for Fleur Visser to study whale behaviour
Fleur Visser was awarded a Veni grant by the Netherlands Organisation for Scientific Research (NWO). She is one of seventeen promising young Leiden scientists, who get the opportunity to develop their own ideas over a period of three years. Veni-funding is part of NWO's Talent Scheme, concerning…
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Music Cognition
Knowledge and culture subproject 1:
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Bachelor programme structure
Study all aspects of human life in the past and take on a broad, historic perspective.
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Chitin in the fungal cell wall: towards valorization of spent biomass of Aspergillus niger
Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Digging for data: the rise and fall of a Miocene mammal biodiversity hotspot in the Vallès-Penedès (Catalonia, Spain)
The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.
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Bankside Plants
What plants grow along ditches in the Leiden region? What does this say about vegetation quality? Could it be better? Naturalis and Leiden University's Center for Environmental Sciences are looking for your help to answer these questions.
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Targeted biomolecule production for therapeutic use
We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.
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A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action
Source: Mediators Inflamm (2014)
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Sustaining Ethical Aquatic Trade (SEAT)
Creating a framework to assess the sustainability of fish farms which will set sustainability standards and give consumers information about the the sustainability and safety of their seafood.
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New History of Fishes. A long-term approach to fishes in science and culture, 1550-1880
From 1550 onwards, a great interest in the natural world developed across Europe. This interest was not only stimulated by a growing knowledge of local flora and fauna, but also by the import of numerous exotic animal and plant species. Think, for instance, of researches and collectors like Gessner…
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Clinical applications of (pharmaco)metabolomics
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…
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Microneedle-mediated vaccine delivery
Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot
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Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model
Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Seeing voices: the role of multimodal cues in vocal learning
Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.
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Cannabinoid receptor 2 as a ‘drugable’ target: kinetic profile of novel receptor ligands
Supervisor: Andrea Martella
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Evaluation of synergistic effects of Chinese herbal medicine and natural compounds on cancers
What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?
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Environmental Humanities in the New Himalayas: Symbiotic Indigeneity, Commoning, Sustainability
Environmental Humanities in the New Himalayas: Symbiotic Indigeneity, Commoning, Sustainability showcases how the eco-geological creativity of the earth is integrally woven into the landforms, cultures, and cosmovisions of modern Himalayan communities.
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Specters of Cavafy
Haunting the future through poetry
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Pre-Columbian social organisation and interaction interpreted through the study of settlement patterns
An archaeological case-study of the Pointe des Châteaux, La Désirade and Les Îles de la Petite Terre micro-region, Guadeloupe, F.W.I.
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Programme
Everyone is welcome at the Leiden Science Family Day. We have set up a programme with a variety of activities for children, teenagers and adults.
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange
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Evaluation of (4-Arylpiperidin-1-yl)cyclopentanecarboxamides As High-Affinity and Long-Residence-Time Antagonists for the CCR2 Receptor
Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.
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Biophysical feedbacks between seagrasses and hydrodynamics in relation to grazing, water quality and spatial heterogeneity
Consequences for sediment stability and seston trapping
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An Update and Expansion of a Meta-Analysis on Shared Book Reading
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Shaping Cultural Landscapes
Connecting Agriculture, Crafts, Construction, Transport, and Resilience Strategies
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Molecular Genetics and Biotechnology (MSc)
In the master’s specialisation Molecular Genetics and Biotechnology at Leiden University students are trained by experts in the areas of molecular biology, microbiology, plant genetics, cellular imaging, animal disease models, and various –omics technologies and the corresponding bioinformatics.
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‘Being a slave’ Indian ocean slavery in local context
What did it mean to be enslaved in in the Indian Ocean world in the 18th and 19th centuries? Over the last decades, historians have mined French, British, Portuguese and Dutch records for quantitative data on the European slave trade. This project focuses on the experience of being a slave and seeks…
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Research
The mission of our group is understanding how science communication works to improve the interaction between science and society. We believe better science communication can improve our society and engage many different groups with science, also improving science.
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Cardiovascular Pharmacology
The Cardiovascular Pharmacology research group headed by Ilze Bot aims to elucidate the mechanisms that underlie atherosclerotic plaque destabilization, which is the key process that leads to acute cardiovascular syndromes such as a myocardial infarction or stroke.
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The International Civil Service: Redefining Its Independence
On 18 April, Alexandre Tavadian defended the thesis 'The International Civil Service: Redefining Its Independence'. The doctoral research was supervised by Niels Blokker and Brian McGarry.
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Bin Your Butt
Have you spotted the special voting bins on campus yet? Send us your suggestions for challenging, non-scientific questions and who knows? Your burning question might just be the next butt-kicker!
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Economic thinking in the Socratic authors and Aristotle
This subproject of 'From Homo Economicus to Political Animal' analyzes Greek economic thinking in late 5th- and 4th-century philosophical circles.
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Cryptic species discovery
Do understudied animals contain hidden species?
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Rethinking Javanese Religion: The Prospect of New Descriptions of Javanese Traditions
This study describes religion in Java.
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)