1,294 search results for “patients” in the Public website
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Patient derived zebrafish xenograft models for personalized treatment of uveal melanoma
PhD defence
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optimal oncolytic virus treatment and diagnostics in high risk melanoma patients
PhD defence
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From reactive to proactive: implementing palliative care for patients with COPD
PhD defence
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The diagnostic management of suspected pulmonary embolism in special patient populations
PhD defence
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Management of disturbed homeostasis in critically ill patients and influence on outcome
PhD defence
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Accelerated Partial Breast Irradiation in elderly patients with early-stage breast cancer
PhD defence
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Advanced echocardiography in characterization and management of patients with secondary mitral regurgitation
PhD defence
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Sexual adverse drug reactions: patient impact and potential for pharmaceutical care
PhD defence
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Triage of stroke patients in the chain of acute stroke care
PhD defence
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Comprehensive measurement of long-term outcomes and costs of rehabilitation in patients with stroke
PhD defence
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Genomic driven treatment and drug rediscovery in patients with advanced cancer
PhD defence
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Biomarkers for the response to immunotherapy in patients with non- small cell lung cancer
PhD defence
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Light-activatable ruthenium-based anticancer prodrugs
Can light-activatable ruthenium compounds be used as a more selective anticancer treatment?
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Extremely shy and genetically close
Investigating neurobiological endophenotypes of Social Anxiety Disorder
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444 years of Leiden University
In 2019 Leiden University was 444 years old. This special birthday called for a special celebration. We celebrated this milestone with the residents of Leiden and The Hague. In, with and for these two cities.
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Metabolomics and Analytics Centre
The ambition of the Metabolomics and Analytics Centre led by Thomas Hankemeier is to develop innovative analytical strategies for metabolomics-driven health monitoring and systems biology studies. Understanding the intricate balance between health, disease and adaptation to challenges relies on the…
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Leiden Academic Centre for Drug Research
Drug development is a complex process in which many parties work together. Every day, the researchers at LACDR devote their energies to developing drugs that are new, better, more efficient and easier to produce. And thus to the millions of patients who know all too well why this research in Leiden…
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Quantitative Systems Pharmacology
This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).
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Topic: Music and health
Music can affect how we feel, think, and behave. But how do we learn about the specifics of people's responses to music so that we can apply this to health and well-being? By looking at characteristics of the music, as well as the differences between listeners, we hope to better understand as well as…
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Rembrandt and Leiden University
Seven large reproductions of works by Rembrandt on seven University buildings in the centre of Leiden reveal the relationship between the painter and the University. Rembrandt van Rijn enrolled in the University in 1620 and painted the portraits of various alumni of the University. The exhibition runs…
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In vivo tracking and biodistribution of protein aggregates
Therapeutic proteins have revolutionized the treatment of many severe diseases like multiple sclerosis, haemophilia, diabetes and many more. Unfortunately, even recombinant proteins with structures (almost) identical to those of their endogenous counterparts often induce the formation of anti drug antibodies…
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An online self-help programme for people with HIV and depressive symptoms
To investigate the effectiveness of an online self-help programme for people with HIV and depressive symptoms.
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Alice in Wonderland-syndrome
FSW Professor Jan Dirk Blom has written a book on Alice in Wonderland syndrome. This is the first scientific book on this rare disorder, which was first described in 1955 by the British psychiatrist John Todd. Todd was inspired by the famous book by Lewis Carroll, in which Alice experiences all kinds…
- Research
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Putting a spin on it: amyloid aggregation from oligomers to fibrils
This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.
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Harnessing zebrafish xenograft models for ocular melanoma treatment discovery
The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…
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Macrophage activation and cholesterol accumulation in atherosclerosis development
Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck
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Characterization of Cell-based medicinal products (CBMPs)
Cell-based medicinal products (CBMPs) show great promise when it comes to the treatment of genetic disorders. However, there is limited knowledge about CBMP stability during their production, storage, and administration to patients. The main focus of my research is the characterization of CBMPs using…
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Topic: Work and health
The research connected to this topic is related to Work and health.
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CT Scanning Skeletal Remains
CT scanning of skeletal remains can tell us about how strong or weak a persons bones were and we can relate that back to diet, activity, and reproductive factors.
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From bed to bench and back to the future
Retrospection over the last 40 years the most important changes in care and research, where transparency accountability and guidelines became leading. On Huntington’s disease and cerebrovascular disorders the most important changes are illustrated.
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Career
The field of science communication is very broad. Below is a list of organisations where SCS students can fulfill internships or where alumni have found jobs.
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Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
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Education in the LUMC
At the Leiden University Medical Centre (LUMC), you will be prepared for the world of tomorrow. We bring research and patient care together in a unique way in our education.
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Leiden Institute for Brain and Cognition
The Leiden Institute for Brain and Cognition (LIBC) is a network that stimulates interdisciplinary exchange of knowledge and expertise on topics related to brain and cognition and focuses on science valorisation and outreach.
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Controlling anxiety in late life (CALL)
Primary Objective: The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in comparison to TAU, LF-TLP will result in a significantly…
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Research lines
Current research at the Skin Barrier and Vaccination group.
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Epilepsy and anxiety: targeting a vicious cycle
How effective is eye movement desensitization and reprocessing therapy in targeting epilepsy-related anxiety?
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Discovering and developing drugs
Improving healthcare with our scientific discoveries: that is the goal of pharmaceutical research at Leiden University. And there’s a lot involved in that. Our research starts with the discovery of the effect achieved by a particular substance, and sometimes continues all the way through to the development…
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Topic: Population health
This research line is part of the living lab of the University’s Population Health interdisciplinary program, located at the LUMC Campus The Hague, where the Leiden University Medical Center collaborates with the Faculty of Governance and Global Affairs and the Faculty of Social and Behavioral Sciences…
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Prediction of human (CNS) target site concentrations in health and disease
Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…
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Replacing fear with something new: Using novelty to unlearn fear.
This project has two main aims: I. Determine when novelty promotes fear extinction. II. Discover the neurobiological mechanisms underlying these effects.
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“Special Needs by Placebo”: Programme to Advise, Normalize And Control its European Administration (PANACEA)
While many healthcare professionals indicate that they frequently use placebo effects and their mechanisms, there is little formal training on how to deal with placebo and nocebo effects in clinical practice. This project aims to address this gap between scientific knowledge on placebo and nocebo effects…
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Programme structure
The master's specialisation Clinical Neuropsychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.
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Collaborative and effective drug development
There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…
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Topic: Novelty and enrichment
One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…
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Research
At Leiden University, researchers from all disciplines work together to find answers and design innovations in the field of artificial intelligence.
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Partnerships
The LACDR represents the core of bio-pharmaceutical research at Leiden University, and we interact closely with our partners:
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Famous Leiden scientists
The oldest university in the Netherlands has produced many well-known scientists. Some of them are known to the wider public; others are perhaps less well known, but their achievements are no less impressive.
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Cancer and heredity
Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.