1,653 search results for “molecular genetics” in the Public website
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The whole world is studying in Leiden
An impressive 1,300 international students from 84 different nations got to know each other at the University in Orientation Week Leiden. Where do they come from and why did they choose Leiden?
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What plant genes can teach us
Just like us, plants also produce growth hormones, and they also go through an ageing process. The study of the genes and mechanisms behind these processes is useful not only for crop breeding and agriculture, but also for medical research. That is the view held by Professor of Plant Developmental Genetics…
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Eyetracking and psychophysiology indicators of social cognition and emotion in adults with Klinefelter syndrome
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Language and self-regulation in XXY
The role of language in self-regulation and social behavior in children with an extra X chromosome
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A computational study of structural and excitonic properties of chlorosomes
The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…
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Leiden biologist receives National Zoology Award
Maurijn van der Zee, evolutionary biologist at the IBL, received the National Zoology Award for his research on the evolutionary success of the insects. The award was handed out last Saturday, the 17th of December, by Professor Jan Kammenga, chairman of the Royal Dutch Zoological society.
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Infrared spectroscopy of astrophysically relevant hydrocarbons
This thesis is about the study of hydrocarbons via infrared spectroscopy.
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Documentation and analysis of !Ora and !Ui languages
This project aims at describing the Khoisan languages !Ora (Korana/Griqua) and !Ui of South Africa.
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Systems dermatology of immune-mediated dermatological diseases: cutaneous T-cell lymphoma
The complex pathophysiology of immuno-dermatological disorders is multifactorial, including environmental, skin microbiome, (epi)genetic and immune dysregulation conditions. This project primarily focuses on the orphan disease mycosis fungoides, a subtype of cutaneous T-cell lymphoma. The current pathophysiological…
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From methanol to medicine – Sustainable microbial production of polyketide antibiotics
Can the pink-pigmented microbe Methylobacterium extorquens be genetically engineered to convert the sustainable raw material methanol into antibiotics?
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Neurogenomics of vocal learning
How does FoxP1 affect auditory perception on a behavioural and genomic level?
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Plant Sciences
The mission of the Plant Science research programme is to contribute to the sustainable production of high quality crops, flowers and high-value bio-based products. This is realised by generating fundamental knowledge of basic biological processes related to development of plants and their interaction…
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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Surface Temperature and the Dynamics of H2 on Cu(111)
Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…
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Genetics proves it: Indo-European did not come to Europe on horseback
Horses were first domesticated in South-West Russia, is the conclusion drawn by an international team of researchers writing in the well-respected journal Nature. Their conclusion resolves a longstanding archaeological question. But, surprisingly enough, this domestication did not contribute to the…
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Glucocorticoids in zebrafish
A novel in vivo model system for studies on glucocorticoid resistance
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‘I am curious and full of passion for understanding molecular chemistry’
Since May, Assistant professor BioTherapeutics Lu Su works in our faculty. Although she is still young, she already worked in many different fields and co-operated on two publications in big scientific journals. How did she become so successful and what motivates her to keep researching the possibilities…
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Diagnostics for mechanical heating in star-forming galaxies
Promotor: F.P. Israel, Co-Promoter: R. Meijerink
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Application procedure
The application procedure is broken down into three parts.
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BRAIN appoints University of Leiden as partner for BEC-Enabled production strain development
BRAIN Biotech and the Leiden University will jointly develop an Aspergillus based production strain with high yield and thus contribute to a bio-based circular economy. The cooperation is based on BRAIN´s molecular tool BEC.
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Richard Karlsson Linnér: ‘I expect a future where a genetic test will be as much a no-brainer as getting X-rayed.’
Assistant Professor Karlsson Linnér, who works at the Department of Economics, is one of the recipients of a Veni grant. His research on the accuracy of preventive genetic testing is a fine example of the intersection of economic science and law.
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Lions in West and Central Africa apparently unique
Lions in West and Central Africa form a unique group, only distantly related to lions in East and Southern Africa. Biologists at Leiden University confirm this in an article published in Scientific Reports.
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Another Brick in the Wall: The role of the actinobacterial cell wall in antibiotic resistance, phylogeny and development
Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.
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Cancer cells: A closer look
What distinguishes a tumour cell from a healthy cell? Researchers are trying to answer this question as precisely as possible. Certain differences could eventually lead to new therapies.
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Using zebrafish to target the Achilles’ heel of cancer
Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.
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Remko Offringa
Science
r.offringa@biology.leidenuniv.nl | +31 71 527 5097
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Stephanus Huijbregts
Faculteit der Sociale Wetenschappen
shuijbregts@fsw.leidenuniv.nl | +31 71 527 1723
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Frank Baas
Faculteit Geneeskunde
f.baas@lumc.nl |
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Marieke Tollenaar
Faculteit der Sociale Wetenschappen
m.s.tollenaar@fsw.leidenuniv.nl | +31 71 527 3454
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Oliver Tuazon
Faculteit Rechtsgeleerdheid
o.m.tuazon@law.leidenuniv.nl | +31 71 527 8838
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Kat Stewart
Science
k.a.stewart@cml.leidenuniv.nl | +31 71 527 2727
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Wil Tamis
Science
tamis@cml.leidenuniv.nl | +31 71 527 2727
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Manon de Visser
Science
m.c.de.visser@biology.leidenuniv.nl | +31 71 527 4882
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Neurodevelopmental risks in young children with an extra X or Y chromosome
This longitudinal study is focused on neurodevelopmental problems in young children with XXY, XXX and XYY, aged 1 to 6 years.
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Highly Accurate Simulations and Benchmarking of Molecule-Surface Reactions
Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.
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Flow: A study of electron transport through networks of interconnected nanoparticles
This thesis describes a study from both a theoreticaL and an experimental point of view.
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Shining Light on Interstellar Matter
Promotor: H.V.J. Linnartz
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Chemical reactivity of O2, CO and CO2 on Cu surfaces
Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.
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Cold gas in distant galaxies
The formation and evolution of galaxies is fundamentally driven by the formation of new stars out of cold gas.
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Cancer and heredity
Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.
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Ahmed Mahfouz: 'The mystery of brain diseases, unravelled cell by cell'
Which brain cell does what, when Parkinson's disease arises? It won't be long before this jigsaw is solved piece by piece. Ahmed Mahfouz, computational biologist, combines bio-knowledge from Leiden with algorithms from Delft and is getting closer to finding the key.
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NWO grants two IBL-proposals by interdisciplinary research consortia
Recently, NWO has decided to grant two interdisciplinary research proposals for national and international consortia submitted by researchers from the Institute of Biology Leiden. One of the proposals is led by Prof. dr. Ariane Briegel, the other one by dr. Remko Offringa.
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The scientists behind LED3
LED3 is the combined effort of three excellent institutes of Leiden University. Through joined hands, we are able to give rise to a more effective early drug discovery pipeline. Let us briefly introduce the three institutes.
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Awards and Grants 2017
An overview of awards and prizes granted to our staff and students in 2017, as well as special appointments and royal distinctions.
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Towards molecular complexity in birth places of stars: Formaldehyde formation from carbon atoms reacting with water ice
Scientists at Leiden University (Netherlands), Stuttgart University (Germany) and Ural Federal University (Russia) have successfully put forward a novel, computed, reaction mechanism that was experimentally tested and show that formaldehyde is formed at much earlier stages in the birthplaces of stars…
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Mononuclear spin-transition materials based on the bapbpy scaffold
Promotor: E. Bouwman, Co-Promotor: S. Bonnet
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Enacting leadership, for and with each other
What makes a good leader, and is there such a thing as a born leader? These are questions that the master's students of the Leiden Leadership Programme (LLP) will explore this year. During the opening seminar, the new participants learn about the programme and share their expectations. 'I want to bring…
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New assessor Bas Schaalje: 'Give our students a voice'
The successor of assessor Marleen van Dorst has been appointed: from September 2019, Bas Schaalje will be the assessor for one year. The master student ICT in Business and the Public Sector wants to make sure that students feel heard by the Faculty.
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The promises and the dark side of stem cells
Geneticist Hans Clevers will give the first Niko Tinbergen lecture new style on 10 December, which is all about stem cells. The young Leiden professors Ariane Briegel and Susana Chuva de Sousa Lopes talk about bacterial noses and the cultivation of egg cells in the lab in short introductory lectures…
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Cell Systems and Drug Safety
The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…