In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…

On 14 December, Jouke Tegelaar defended the thesis 'Single supervision, single judicial protection? Towards effective judicial protection in Single Supervisory Mechanism composite procedures'. The doctoral research was supervised by Matthias Haentjens and Willemien den Ouden.

Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander

To what extent does the Law Ombudsperson for Children achieve its goals as intended by the legislator when introducing the law?

If you replace the standard hydrogen atoms in ice with a heavier variant, something odd happens. The volume occupied by the molecules increases by 0.1 per cent. Leiden chemist Jörg Meyer and his colleagues have created a theoretical model that describes this behaviour. Their research appeared on the…

Lecture

To be able to measure small forces or small deviations from Boltzmann, the external vibrations at the resonance frequency must be very low. To achieve this, we have developed a very soft vibration isolation system and combine it with several other measures to reduce vibrations in our dilution refrigerators.…

Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.

Plant Sciences' contribution to the Development & Disease research theme is to unravel the processes that allow plants to adapt to changing abiotic and biotic environmental conditions or stresses, with the aim to contribute to the sustainable production of food, flowers and bio-based products using…

Newspaper NRC and popular scientific magazine New Scientist write about Corentin Coulais’ research on one-way-traffic metamaterials. He published a paper on this subject in Nature on February 13.

Martin van Hecke published an article in Nature, together with physicists from AMOLF and UvA. They have developed a metamaterial that folds itself up, even in multiple steps. Van Hecke appeared in the following media.

How does the photoregulation mechanism work in detail?

The aim of the research programme is to provide insight into the cognitive processes and brain mechanisms that underlie reading, arithmetic and learning in general.

What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?

Which immune mechanisms are involved in host defense against Staphylococcal infection?

This thesis describes the use of the evolutionary approach in the study of language change, aiming to provide a better insight in the mechanisms that play a role in language change and to validate this approach in the field of language change.

Why is Crossnational and Cross-cultural agents such as Henrich Carloff and Willem Leyel important when studying Early Modern expansion?

In this article, Lydie Cabane, Assistant Professor at the Institute of Security and Global Affairs, and Martin Lodge address the question of how to manage banking crises, a question that has gained prominence since the banking crisis of 2007-2009. This article sets out the rationale for regulating for…

The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

Industrial Ecology

Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar

This research focuses on a historical/social analysis of a selected corpus of novels from modern Turkish literature which have the common theme of migration from Anatolian towns and villages to Istanbul, and the immigrants’ struggle in this city against various exclusion mechanisms.

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

Sevil Cakir-Kilincoglu defended her thesis on 18 December 2019

Promotor: Roeland M.H. Merks

How does the development of digital technologies impact society, and law/regulation within that society?

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

The focus of the dissertation

Do humans and zebra finches share cognitive mechanisms that are important for speech perception?

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

On May 31st, Bobby Ruijgrok succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Bobby on this great result.

The research group of Semonti Bhattacharyya at the Leiden Institute of Physics studies quantum transport measurements in Van der Waals heterostructures.

Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

What are the mechanisms involved in the reconciliation of value conflicts and which interventions are capable of resolving such disputes?

Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency

Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

Promotor: Prof.dr. T. Schmidt

What is the role of emotion regulation in coping with interpersonal feedback?

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

The research programme Industrial Ecology aims to support the ecological transformation of society and environment towards sustainability. The research subject is Industrial Ecology in its broadest definition, covering environmental systems analysis, and incorporating the social and economic aspects…

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Promotor: V. Vitelli, Co-promotor: J. Paulose

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli