1,503 search results for “mathematisch and statistical modelling” in the Public website
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Postdoc Three-dimensional simulation models of plant tissue mechanobiology (1.0 FTE for three years)
Science, Mathematical Institute (MI)
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Mathematical modeling of cellular stress pathways for mechanistic understanding of chemical-induced liver injury
Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…
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underlying inflammation and infection control: insights from the zebrafish model
This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.
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Research
Research of the Methodology & Statstics unit of the Institute of Psychology at Leiden University.
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Beyond the Born-Oppenheimer Static Surface Model for Molecule- Surface Reactions
Several techniques are explored for going beyond the born-oppenheimer static surface model for molecule-surface reactions.
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Discovering the preference hypervolume: an interactive model for real world computational co-creativity
In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.
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Admission and Application
Are you interested in studying the Methodology & Statistics in Psychology master's programme at Leiden University? Find out how to apply by following the step-by step guide in the application and admission section.
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Programme structure
The master's specialisation Methodology and Statistics in Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.
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The Chara plasma membrane system : an ancestral model for plasma membrane transport in plant cells
Multicellular giant algae Chara species have been widely used in physiological studies for decades.
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Understanding membrane fusion at the molecular level using a biomimetic model system
How can the transport of molecules in living cells help to target medicines at exactly the right place?
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Enumeration and Simulation of Lattice Polymers as Models for Compact Biological Macromolecules
Promotores: H. Schiessel, G.T. Barkema
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Zebrafish embryos and larvae as a complementary model for behavioural research
Promotor: Prof.dr. M.K. Richardson
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Advances in Survival Analysis and Optimal Scaling Methods
This thesis is based on five papers on several topics.
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PKPD and disease modelling in therapy development for amyotrophic lateral sclerosis (ALS)
We aim to gain a better understanding of the natural disease progression of ALS in order to improve clinical trial design and analysis and to support drug discovery and clinical development of new drugs.
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Seascape Corridors: How modelling routes through the sea can illuminate early island culture
What are the capabilities or limitations of traveling between islands and how does this reflect seasonal variation? Is it possible to show higher levels of connectivity between islands based on generated pathways between several sites on two separate islands?
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adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Why Leiden University?
The two-year research programme Applied Mathematics offers courses at an advanced level. There is a large degree of freedom in choosing one’s own topics. Some of the courses are given at national level, in the Dutch Mastermath programme. The programme concludes with the preparation of a master’s the…
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Why Leiden University?
The Mathematics master’s programme will guarantee a thorough theoretical basis and will make sure you are ready to work in a multidisciplinary environment. Your mathematical degree will give you the right tools to operate successfully on the international market.
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Why Leiden University?
The Mathematics and SCS master specialisation gives you the opportunity to combine Mathematics research with different aspects of science communication.
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Education
The Mathematical Institute offers a bachelor programme in Mathematics and master programmes in Mathematics and in Statistical Science. The institute also teaches many mathematics and statistics courses in other academic programmes of the university. About 65 PhD students work on a thesis in a small…
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Gerard van Westen: 'Our model predicts what candidate drugs do in your body'
He’s a fast and animated speaker, which is only logical because Gerard van Westen is driving an express train. His destination? A virtual human, consisting of algorithms that predict what an administered substance will do in the body. The train is already a long way down the line and the pharmaceutical…
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Contact
You may contact LUXs through any of its members or secretariats of its participating institutes. You may also reach the steering group through its chair or secretariat.
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A New Model of Global Governance in International Tax Law Making (GLOBTAXGOV).
Assessing the feasibility and legitimacy of the current model of global tax governance and the role of the OECD and EU in international tax law-making.
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Cultural evolutionary modeling of patterns in language change. Exercises in evolutionary linguistics
This thesis describes the use of the evolutionary approach in the study of language change, aiming to provide a better insight in the mechanisms that play a role in language change and to validate this approach in the field of language change.
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European Experts in Inflammation: from the molecular players to animal models and the bedside
How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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A monodromy criterion for existence of Neron models and a result on semi-factoriality
In the first part, we introduce a new condition, called toric-additivity, on a family of abelian varieties degenerating to a semi-abelian scheme over a normal crossing divisor.
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Innate immunity, developmental speed and their trade-offs in two hexapod models
This thesis focuses on important life history traits and their trade-offs using two hexapod models. Particularly, the trade-off between immune defense and embryonic developmental speed is a central theme of this study.
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Modelling the interactions of advanced micro- and nanoparticles with novel entities
Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.
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Flow through EMT Facilities Applying Dynamic Behavioral Simulation Models
This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…
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Training European experts in multilevel bioimaging, analysis and modelling of vertebrate development
How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?
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Organisation
The staff members of the Methodology & Statistics unit are members of various boards and committees.
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About the programme
The master's specialisation Methodology and Statistics in Psychology includes courses, a thesis and an internship. Teaching takes place in the form of seminars and small-group lectures and practicals, and is assessed primarily by written coursework and reports of empirical projects carried out individually…
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Catherijne Knibbe
Science
c.knibbe@antoniusziekenhuis.nl | +31 71 527 6329
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Child Cancer Fund subsidises statistical research
Marta Fiocco, professor in the Mathematical Institute, has received a grant for analysing data on chemotherapy in children suffering from leukaemia. The work involves developing and applying new statistical methods that will help determining the optimal dose of chemotherapy.
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Eiko Fried
Faculteit der Sociale Wetenschappen
e.i.fried@fsw.leidenuniv.nl | +31 71 527 2727
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Richard Gill
Science
gill@math.leidenuniv.nl |
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Max van Haastrecht
Science
m.a.n.van.haastrecht@liacs.leidenuniv.nl | +31 71 527 4799
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Jacq Meulman
Science
j.j.meulman@math.leidenuniv.nl | +31 71 527 2727
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Rob Tijdeman
Science
tijdeman@math.leidenuniv.nl | +31 71 527 4831
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Xaver Funk
Faculteit der Sociale Wetenschappen
s.x.funk@fsw.leidenuniv.nl | +31 71 527 2727
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Bayes and Networks
Promotor: A.W. van der Vaart
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Accurate modeling of the dynamics of dissociative chemisorption on metal surfaces
Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.
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Statistics for the benefit of the patient
Marta Fiocco has been appointed as of 1 April as professor of applied mathematics, in particular medical statistics. Fiocco's appointment is at the Faculty of Science and at the Leiden University Medical Centre (LUMC). She conducts research into 'personalised medicine', tailor-made medicines for cancer…
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Tense-Switching in Classical Greek A Cognitive Approach
The recently published book 'Tense-Switching in Classical Greek A Cognitive Approach' by Arjan Nijk provides classicists and linguists in general with a complete account of the 'historical present' in Classical Greek.
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About the programme
The two-year Master in Statistics & Data Science consists of 120 European Credit Transfer System (EC) points. It consists of a core set of mandatory courses, electives and a Master's Thesis Project.
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Multivariate Humanities
This case study-based textbook in multivariate analysis for advanced students in the humanities emphasizes descriptive, exploratory analyses of various types of data sets from a wide range of sub-disciplines, promoting the use of multivariate analysis and illustrating its wide applicability. Fields…
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Mark de Rooij appointed SAIlS Professor
As of April 2022, Mark de Rooij has been appointed SAILS Professor AI and Data Theory at the Institute of Psychology. This position will enable him to contribute to the goal of the interdisciplinary programme: to build on and expand the current expertise on AI within Leiden University, working from…
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Astrophysical plasma modeling of the hot Universe: Advances and challenges in high-resolution X-ray spectroscopy
Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.