1,968 search results for “induced pluripotent system cell” in the Public website
-
Measures and Matching for Number Systems
This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.
-
Interaction between legal systems
Interaction between Legal Systems acknowledges that law-making and law enforcement are increasingly taking place on various levels: in a global context, in EU context, on a national level and in a private law framework. These levels influence each other, sometimes directly, on the basis of a hierarchical…
- Scheduled maintenance educational systems
-
Martina Chirilus-Bruckner
Science
m.chirilus-bruckner@math.leidenuniv.nl | +31 71 527 4837
-
Frank Schaftenaar
Science
f.h.schaftenaar@lacdr.leidenuniv.nl | +31 71 527 5134
-
Evolutionary traps – Balanced lethal systems
How do balanced lethal systems originate and persist in nature?
-
Nano-scale electronic structure of strongly correlated electron systems
In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.
-
Membrane Fusion Mediated Intracellular Delivery of Lipid Bilayer Coated Mesoporous Silica Nanoparticles
Alexander Kros and co-workers describe how mesoporous silica nanoparticles (MSNs) are delivered into cells via membrane fusion thereby omitting endocytosis pathways. Fusion is induced by a pair of complementary coiled-coil lipopeptides inserted into the membrane of cells and in the bilayer of lipid-coated…
-
Dynamics of coupled quantum systems
Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…
-
Biological, Soft and Complex Systems
The research groups within the biological, soft and complex systems research area study the physics of a broad range of biological and soft materials. This spans both experimental and theoretical research.
-
The endocannabinoid system in zebrafish larvae
In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.
-
The role of auxin in somatic embryogenesis
What is the role of auxin in the initiation and process of somatic embryogenesis?
-
Non-canonical gender systems
Grammatical gender is famously the most puzzling of the grammatical categories. We have a solid typology of gender systems, yet exciting and unexpected patterns keep turning up which defy easy classification and straightforward analysis. Some of these question, stretch or threaten to cross the outer…
-
Medical Systems Biophysics and Bioengineering
The ambition of the Medical Systems Biophysics and Bioengineering group led by Alireza Mashaghi is to develop and use physics and engineering concepts and tools for pathophysiology, diagnostics and therapy.
-
Non-Canonical Gender Systems
This book explores the boundaries of the category of gender and their theoretical significance within the framework of Canonical Typology.
-
Nicolas Navarre
Science
n.h.navarre@cml.leidenuniv.nl | +31 71 527 2727
-
Duality for Interacting Particle Systems
Duality, stochastic processes
-
Dormancy in stochastic interacting systems
Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.
-
United States
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.
-
Leiden Study System
At Leiden University we believe it is important that you receive the right kind of support in your choice of study and while you study. This is why we use what we call the ‘Leiden study system’ to help you make a success of your study from start to finish.
-
Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
-
Socially Embedded AI Systems
This interdisciplinary research project explores several adaptive machine learning methods which can give insight into the interaction between human and machine. The ultimate goal is open and natural communication between humans and AI that should result in mutual trust, cooperation and coordination…
-
Projects
Research projects
-
characterization of plant exudates and their correlation with plant defense systems
Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.
-
Véronique Ongenae
Science
v.m.a.ongenae@biology.leidenuniv.nl | +31 71 527 5075
-
Grant: Dr. Amanda Foks receives a prestigious Junior Postdoc fellowship from the Dr. E. Dekker stipendium awarded by the Dutch Heart Foundation
Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.
-
Sensing drug responses of single cells using optical tweezers
Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.
-
Development of cross-protective influenza A vaccines based on cellular responses
Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…
-
Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
-
glucocorticoid and mineralocorticoid receptor signaling in the innate immune system
Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?
-
In vitro model systems for studying the impact of organic chemicals on the skin barrier lipids
This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.
-
300 million euros for new international stem cell consortium
The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…
-
Connecting dots between natural and artificial Photosynthesis
Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.
-
Martin Moerings
Faculteit Rechtsgeleerdheid
l.m.moerings@law.leidenuniv.nl | +31 71 527 2727
-
Wenyu Wan
Faculteit der Sociale Wetenschappen
w.wan@fsw.leidenuniv.nl | +31 71 527 2727
-
Multi-Biomarker Pharmacokinetic-Pharmacodynamic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
-
Research into the academic system
Research into research improves the academic system. CWTS studies and evaluates the academic system in various ways. One way is to provide information on the productivity and impact of academics by documenting how many publications they or their universities produce and how often these publications…
-
Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
-
Christine Mummery
Faculteit Geneeskunde
c.l.mummery@lumc.nl | +31 71 526 9300
-
Tessa Vergroesen
Science
t.m.vergroesen@biology.leidenuniv.nl | +31 71 527 4912
-
Crossed product algebras associated with topological dynamical systems
Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov
-
Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
-
TRIPS: Thrips Reduction In Production Systems
Increasing above- and belowground biodiversity in arable leek cultivation to stimulate pest control by natural enemies.
-
Proper and improper uses of MCDA methods in energy systems analysis
In this article, Marco Cinelli, assistant professor at Leiden University College The Hague, examines proper and improper uses of Multiple Criteria Decision Analysis (MCDA) methods in energy systems analysis.
-
Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
-
Leiden scientists map cell types in fetal kidney
Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…
-
Cells ‘walk’ to firm ground
A new mathematical model may explain how body cells get their shapes and what makes them move within a tissue. The model provides fundamental knowledge for applications in tissue engineering, amongst other things. Publication in open-access journal iScience.
-
Systems pharmacology of human neuroendocrine disease entities
An important hormone excreting gland in the human body is the pituitary
-
Aggressiveness of cancer cells halted
Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.
-
Agrobacterium-mediated protein therapy for genome editing
Is translocation of nucleases possible via Agrobacterium T4SS and is it efficient enough for mutagenesis?