1,106 search results for “carlo electron microscopy cryo-em” in the Public website
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Kroese-Duijsters Symposium 2024
The Kroese-Duijsters Symposia aim to provide researchers from different fields and different career stages to meet in an informal setting, to stimulate discussions and to start new collaborations. The Kroese-Duijsters Symposia started in 2022 and we are pleased to invite you to the 3rd Kroese-Duijsters…
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Development of new chemical tools to study the cannabinoid receptor type 2
The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.
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Colloquium: Imaging Electrochemical Reactions by Operando Optical Microscopy
Lecture
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Briegel winner in global competition by the Moore Foundation
Ariane Briegel, Professor of Ultrastructural biology in Leiden, has received a prestigious incentive from the Gordon and Betty Moore Foundation. With the grant of 800,000 euros, Briegel will set up a new research line into studying symbiotic interactions on the nanoscale.
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Research
Combining different disciplines, researchers work together to formulate innovative solutions to societal problems.
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COVID-19 vaccine
Leiden researchers are helping develop safe COVID-19 vaccines.
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Self-assembly properties and applications of metal-binding peptides and proteins
It is estimated that approximately 30% of all proteins require a metal to function. Investigating the relationship between metal-binding and peptide/protein folding allows us to uncover fundamental rules for creating metallo-peptides and proteins, which in turn leads to the creation of new structures,…
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New imaging technology to assess early drug success
Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…
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Searching by Learning: Exploring Artificial General Intelligence on Small Board Games by Deep Reinforcement Learning
In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…
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Developing new therapies to fight muscle disease
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…
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Unraveling the mechanism of multicopper oxidases: from ensemble to single molecule
Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma
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Dangerous microbes in lower level safety lab? A new technique could make it possible
Researchers need to work in specialized environments when they work with dangerous bacteria and viruses. These microbes spread easily, so only in labs with a high biosafety levels they can be studied. Unfortunately, to look at the microbes properly, expensive microscopes are needed that are not always…
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Participants
The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).
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Paradox in superconductivity at high temperature
Nature publishes an article on a paradoxical discovery in superconductivity. Physicists are searching for superconductivity at high temperatures so that less cooling is needed in for example MRI machines. News & Views article by Prof. Jan Zaanen in the same issue of August 19th.
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A Grammar of Tagdal
On the 21st of September, Carlos Benítez-Torres successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Carlos on this achievement!
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Explorations of Water Oxidation Catalysis in Explicit Solvent
In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.
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Merijn de Bakker
Science
m.a.g.de.bakker@biology.leidenuniv.nl | +31 71 527 5043
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Fons Verbeek
Science
f.j.verbeek@liacs.leidenuniv.nl | +31 71 527 5773
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Abolfazl Sajadi
Science
a.sajadi@liacs.leidenuniv.nl | +31 71 527 4799
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Daniel Vale
Faculteit Rechtsgeleerdheid
d.s.vale@law.leidenuniv.nl | +31 71 527 8838
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Pablo Ilgemann
Science
p.m.ilgemann@cml.leidenuniv.nl | +31 71 527 2727
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Jörg Meyer
Science
j.meyer@chem.leidenuniv.nl | +31 71 527 5569
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Molecular and Nano-Engineering with Iron, Ruthenium and Carbon: Hybrid structures for Sensing
Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.
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PhD student in Biochemistry, Structure and Function of Archaeal Chromatin
Science, Leiden Institute of Chemistry (LIC)
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Platinum electrochemistry through a magnifying glass
In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.
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The poetics of negativity in sound based artistic practice
This research proposal focuses on the investigation of the poetic potentials of negativity through the exploitation of failure in sound based artistic practices - a context that has not been extensively addressed.
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Drug safety Sciences
Our research in the area of safety sciences aims to increase the mechanistic understanding of cellular toxicity of drugs and, in a broader sense, chemicals.
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The robust qubit: the Zen particle
A couple of years ago, theoretical physicist Carlo Beenakker tracked down the Majorana particles and inspired Leo Kouwenhoven from TU Delft to try to create them in a superconducting nano-structure. He succeeded in doing so in 2012, and the news made headlines around the world. But a lot of work still…
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Nano-scale Electronic Structure of Strongly Correlated Electron Systems
PhD defence
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Functional fluorescent materials and migration dynamics of neural progenitor cells
In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells.
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Single-molecule microscopy in zebrafish embryos
PhD defence
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Spin-momentum locking in oxide interfaces and in Weyl semimetals
Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.
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Huub de Groot
Science
groot_h@chem.leidenuniv.nl | +31 71 527 4539
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Microcoil MRI of Plants and Algae at Ultra-High Field: An exploration of metabolic imaging
This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).
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Geert-Jan Kroes
Science
g.j.kroes@chem.leidenuniv.nl | +31 71 527 4396
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Renewable Energy
The transition to new and renewable energy sources should be completed by 2050. Researchers in various disciplines at Leiden University are conducting unique research that will help us make this transition and reduce CO2 emissions.
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New ONEM Microscope to combine best of two worlds
Leiden physicists have been awarded 1.5 million euros for developing a hybrid microscope that provided nanometer-resolution. 'The idea is to combine the resolution of electron microscopy with the pros of optical microscopes.'
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ZF-HEALTH - Zebrafish Regulomics for Human Health
How can zebrafish research help understanding human diseases?
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Institute of Biology
Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’
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Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotor: Prof.dr.ir. T.H. Oosterkamp, N. de Jonge
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Sparsity-Based Algorithms for Inverse Problems
Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…
- Program in English
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Optoplasmonic detection of single particles and molecules in motion
Detecting nanoscopic objects plays an important role in nanoscience in particular, in the rapidly growing field of nanobiology. The forebear to modern super-resolution microscopy for single molecule investigation, is fluorescence microscopy.
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Insights into microtubule catastrophes: the effect of end-binding proteins and force
For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.
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New technique for Imaging Charge Transport in a Graphene Layered Cake
Leiden Physicists have developed a new technique to visualize electrical conductance in sheet-like nano materials. It shows great promise for devices based on a new family of materials—the ‘Van der Waals materials’. The physicists, who won the 2015 Dutch Vacuum Society prize for their work, present…
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Microbial Sciences
In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.
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Rough-and-tumble play and the regulation of aggression in preschoolers
How does preschoolers’ play style relate to their aggressive impulses?
- Technical Program Chairs
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5 Grants for Leiden Physics in 10 years ERC
This weeks marks the 10th anniversary of the European Research Council. For the past decade, the council has contributed to many scientific projects all over Europe, including Leiden University. It has funded almost 7,000 researchers, leading to just short of 100,000 scientific articles. A total of…