Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

The authors detail the transnationality of terrorist organisations, including fundraising, communications, alliance-forming, movement and target selection.

Interest group Animal Rights has started a test case to prompt the Netherlands Food and Consumer Product Safety Authority (NVWA) to tackle farmers who do not adequately protect their livestock against wolves. The test case concerns a rejected enforcement request to the NVWA. In it, the NVWA were called…

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

Strengthening a cancer patient's own immune system so that the body itself can better destroy cancer cells. This is at the heart of immunotherapy, the most promising progress in cancer treatment in recent years. In order to drive this development further, the Netherlands Cancer Institute-Antoni van…

A deliberate attack on a tangible element of a culture, such as a temple, is often also an attack on intangible elements: the religion or religious customs. Equally, the intangible can be attacked without the involvement of the tangible, for example the brutal curtailment of rights. How are these reflected…

Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck

Chemotherapy that does nothing until you irradiate it with light. Sylvestre Bonnet receives a Vici grant of 1.5 million euros for the development of this treatment. The Leiden chemist wants to build a new molecule to fight tumours that are at the time still difficult to treat.

Six PhD candidates from the Institute for History took part in a pilot project targeted at career development. Between September and December 2016 group meetings and individual coaching sessions helped them position themselves better on the job market outside of academia.

Holocaust scholars Barbara Engelking and Jan Grabowski will jointly hold the Cleveringa lecture on November 26. They were accused of defamation in Poland for a book they co-edited. How has this affected them? ‘This is an attempt to wear us down.’

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

MT3 is a globally unique programme led by professors and reference authors that cover the most up-to-date knowledge possible in the area of Transfusion Medicine and Cellular and Tissue Therapy. It provides access to high quality knowledge and skills via a completely online system.

Are you considering starting with the Master's Transfusion Medicine and Cellular and Tissue Therapies? Please feel free to contact us if you have any questions.

The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…

The master's specialisation Child and Adolescent Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.

Project TARGET is a research project aimed at the relation between the illegal arms trade and firearm violence. In a study conducted in seven countries, the researchers took a look at the differences and similarities. Katharina Krüsselmann and Marieke Liem took a closer look at the situation in the…

Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

PhD defence

Ewa Snaar-Jagalska, Shuning He and colleagues from IBL, LION and LACDR reported on a new zebrafish study to understand micrometastasis of human cancer cells. They discovered a novel role for neutrophils in assisting metastasis formation, which provides critical insights for anti-cancer therapies.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

Political scientist Corinna Jentzsch received an NWO Veni grant for her research on the conditions of collaboration between militias and state forces and its consequences for safety and political order.

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.

Courses cover a broad range of relevant subjects and provide in-depth theoretical knowledge as well as training in practical skills and advanced research tools.

Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…

Find out how to apply for Transfusion Medicine and Cellular and Tissue Therapies.

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

PhD defence

The Leiden Index of Depression Sensitivity (LEIDS) measures cognitive reactivity (CR) to sadness, an aspect of cognitive vulnerability to depression, conceptually similar to rumination.

To investigate the effectiveness of an online self-help programme for people with HIV and depressive symptoms.

Effectiveness of an early intervention program for anxiety-prone toddlers in the Netherlands