1,687 search results for “role werkt in rianne environmental” in the Public website
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The diverse roles of integrin α3β1 in cancer: Lessons learned from skin and breast carcinogenesis
In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.
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Zebrafish models for disease and environmental stress
We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.
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More laws, more problems? The role of (Roman) law in society according to Cornelius Tacitus
Whether implicitly or explicitly, we all have ideas about how the law is supposed to function, whose interests it should represent, and what role it should play in society. This project explores the ways in which these questions are addressed in the works of the Roman historian Publius Cornelius Tacitus…
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Resilient Ecosystems and Flourishing Communities
Exploring the Meanings of Lands and Forests as an Avenue for Mutual Development of People and Nature in Ghana
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International Environmental Obligations and Liabilities in Deep Seabed Mining
On Tuesday 26 June Linlin Sun will defend her dissertation entitled ‘International Environmental Obligations and Liabilities in Deep Seabed Mining’. The dissertation has been written under the supervision of prof. dr. N.J. Schrijver and prof. dr. E.C.P.D.C. De Brabandere.
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The role of research in university teaching: A comparison of Chinese and Dutch teachers
The main interest of this research concerns the beliefs and perceptions of Chinese and Dutch university teachers regarding the role of research in university teaching, and how these beliefs and perceptions can be explained by their cultural, institutional and individual background characteristics.
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The role of 14-3-3 proteins in ion homeostasis in the yeast Saccharomyces cerevisiae
We aim to understand ion homeostasis in the model eukaryote S. cerevisiae.
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An overall picture: the environmental impacts of a new solar cell technology
A more efficient solar panel sounds great. But what if these new panels consume more toxic materials, or their production consumes a lot of energy? Leiden environmental scientists, together with colleagues from the Fraunhofer ISE, address this multifaceted question in a new publication in the prestigious…
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The important role of stratum corneum lipids for the cutaneous barrier function
The skin protects the body from unwanted influences from the environment as well as excessive water loss. The barrier function of the skin is located in the stratum corneum (SC).
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The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions
This thesis describes the functional analysis of the Arabidopsis AHL15 gene.
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Environmental Sciences Research Prize awarded to David Font Vivanco
The Environmental Sciences Research Prize 2012 has been awarded to CML researcher David Font Vivanco by the Environmental Scientists Association of Catalonia.
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Jolanda van der Vliet 'Better International Protection Environmental Refugees'
On Thursday 7 May, Jolanda van der Vliet obtained her PhD based on her dissertation 'The International Protection of Environmental Refugees. A human rights-based, security and State responsibility approach.' The defence was held online. Jolanda worked on her dissertation under the supervision of the…
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Investigations on the role of impaired lysosomes of macrophages in disease
The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.
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Unraveling the role of signaling networks controlled by Grainyhead like transcription factor in breast cancer subtypes
This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…
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Mission adapted: the hidden role of governors in shaping central bank operating missions in Hungary
In this article, Makszin developed a conceptual framework for the operating mission of an independent Central Bank and traced changes in the operating mission of the Hungarian National Bank over its recent 27-year history together with Sebők and Simons. This study aims to understand the dynamics of…
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Civil Society against Corruption in Ukraine: Political Roles, Advocacy Strategies and Impact
This project aims to provide evidence-based knowledge on the conditions for successful anti-corruption activism in Ukraine.
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The role of lipids in the barrier function of the skin
The outermost layer of the skin, the stratum corneum (SC), is responsible for the skin barrier function, protecting the body from pathogens, chemicals and other unwanted substances from the external environment. The SC lipid matrix provides the only continuous pathway through the SC and is considered…
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Bestrijdingsmiddelenatlas (BMA) - Pesticide Atlas of Dutch surface waters
Improving environmental risk assessment of pesticides in surface waters
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A study on PsbS and its role as a pH sensor
Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.
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Understanding protein complex formation: The role of charge distribution in the encounter complex
Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.
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The Social Ties that Bind: Unraveling the Role of Trust in International Intelligence Cooperation
Together with Pepijn Tuinier and Thijs Brocades Zaalberg, Sebastiaan Rietjens researched the role of trust in an international intelligence cooperation.
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The role of research in university teaching: a comparison of Chinese and Dutch teachers
This dissertation reports on the beliefs and perceptions of Chinese and Dutch university teachers regarding the role of research in university teaching and how these beliefs and perceptions can be explained by their cultural, institutional and individual background characteristics
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Developing drawing skill: Exploring the role of parental support and cultural learning
Drawing is one of the most unique human behaviours. Like language, drawing is a mode of communication and a cognitive tool that from an early age allows us to interact with others. Is the early development of drawing skill influenced by the social environment? If so, how?
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Systematic investigations into the role of ceramide subclass composition on lipid organization and skin barrier
The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.
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Central role of Claudin-1 in lesional but not in non-lesional atopic dermatitis
Source: Journal of Investigative Dermatology, Volume 134, pp. S44-S44 (2014) ISBN: 0022-202X
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Cutaneous barrier dysfunction in atopic eczema: the role of stratum corneum lipids
Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 148-148 (2015) ISBN: 0142-5463
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Mycobacterial cell wall-deficiency and its role in the persistence of tuberculosis
What is the role of cell wall-deficiency in the persistence of tuberculosis?
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T-cells in atherosclerosis: mechanistic studies revealing a protective role in the plaque microenvironment
Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.
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Role of near-surface environment in tuning electrochemical CO2 reduction reaction and H2 evolution reaction
This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…
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Media on environmental impact of food research by Paul Behrens
The environment also benefits when people follow national nutritional guidelines, Paul Behrens demonstrated in research published in PNAS. The publication attracted media attention both at home and internationally.
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Designing 'context-specific' regional innovation policy: a study on the role of regional government in six European regions
Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…
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Rutger Hoekstra
Science
r.hoekstra@cml.leidenuniv.nl | +31 71 527 2727
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Kees Musters
Science
musters@cml.leidenuniv.nl | +31 71 527 7461
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Surendra Balraadjsing
Science
s.balraadjsing@cml.leidenuniv.nl | +31 71 527 2727
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Uncertainty and Employees’ Daily Innovative Work Behavior: The Moderating Role of Ambidextrous Leadership
Bernard Bernards examines constraints on innovation by focusing on cognitive uncertainty as a personal state that may affect innovative work behavior.
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The role of AGC3 kinases and calmodulins in plant growth responses to abiotic signals
Promotor: Prof.dr. P. Hooykaas, Co-promotor: Dr. R. Offringa
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The role of expectancies and avoidance learning in the maintenance of somatic symptoms
Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.
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A family affair? Exploratory insights into the role of family members of those who joined jihadist groups
Since 2012, thousands of individuals have traveled from Western countries to join jihadist groups in Syria and Iraq. While much has been written about these individuals, only sparse attention has been paid to the social environment of these jihadist travelers and, more specific, the role of family members…
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Lipid to protein ratio plays an important role in the skin barrier function of atopic eczema patients
OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.
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The mystical kiss of the mouth. The role of images and imagery in medieval spirituality (1100-1500)
How can the importance of the image in late medieval spirituality be understood in the context of the love mysticism inspired by the imagery of the Song of Songs?
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Congruence between voters and parties: The role of party‐level issue salience
The level of congruence between parties and their voters can vary greatly from one policy issue to another, which raises questions regarding the effectiveness of political representation. We seek to explain variation in party–voter congruence across issues and parties.
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The role of zebrafish larvae for studying anxiety-like behaviour
The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.
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Democratic Secrecy: A Philosophical Study of the Role of Secrecy in Democratic Governance
The starting hypothesis of the project is that secrecy is not always inimical to democratic governance as conventional wisdom has it.
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Analogy, Technical Reason, and Living Beings: The Role of Analogy in Representing Kant's Concept of Naturzweck
This dissertation concerns the role of analogy in Kant’s “Critique of the Teleological Power of Judgment”, especially the role of analogy for the formation of the concept of a natural end (Naturzweck). A ‘natural end’ is a ‘regulative concept’ of the reflective power of judgment, that is, a heuristic…
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Dutch Shipping and the Environment, 1621-1939
This project explores themes at the intersection of maritime history and environmental history by looking at the problems Dutch ships encountered in the different climates of the Atlantic and Indian Ocean worlds, and the solutions they could provide.
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Role of non-homologous end-joining in T-DNA integration in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater
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The role of ceramide chain length distribution on the barrier properties of the skin lipid membranes
The skin barrier function is provided by the stratum corneum (SC). The lipids in the SC are composed of three lipid classes: ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs) which form two crystalline lamellar structures. In the present study, we investigate the effect of CER chain length…
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Computational modeling of tumor growth and metastasis and the role of the immune system in tumor destruction
In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.
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The Role of the United Nations General Assembly in Advancing Accountability for Atrocity Crimes: Legal Powers and Effects
On 20 October 2021 Michael Ramsden defended the thesis 'The Role of the United Nations General Assembly in Advancing Accountability for Atrocity Crimes: Legal Powers and Effects'. The doctoral research was supervised by Prof. N.M. Blokker.
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More than a digital system: how AI is changing the role of bureaucrats in different organizational contexts
In this paper, Sarah Giest and Bram Klievink highlight the effects of AI implementation on public sector innovation. This is explored by asking how AI-driven technologies in public decision-making in different organizational contexts impacts innovation in the role definition of bureaucrats.